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Protein Ontology Report - TP53/iso:1/Sumo:1

PR:000027840 - http://purl.obolibrary.org/obo/PR_000027840
Ontology Information
PRO ID PR:000027840 Show OBO stanza
PRO name cellular tumor antigen p53 isoform 1 sumoylated 1
Synonyms
PRO-short-label: EXACT: TP53/iso:1/Sumo:1
Definition A cellular tumor antigen p53 isoform 1 that has been sumoylated on a conserved Lys residue located within the regulatory C-terminal domain. While p53 sumoylation at Lys386 inhibits p300 mediated p53 acetylation (at Lys382 and Lys 373), p53 acetylation by p300 remains permissive for subsequent Lys386 sumoylation. Lys386 sumoylated p53 exists as a tetramer in solution. Example: UniProtKB:P04637-1, Lys-386, MOD:01149. [PMID:19339993, PRO:PD]
PRO Category modification
Parent PR:000003036 cellular tumor antigen p53 isoform 1
Term Hierarchy Visualization DAG     OLS     Cytoscape

Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

TP53/iso:1/Sumo:1 forms found in complexes
TP53/iso:1/Sumo:1 Component Complexes
PR:000027841 hTP53/iso:1/Sumo:1 PR:000027844 p53 complex sumoylated 1 (human)

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