PRO Entry Report - PR:000035703

Protein Forms Complex Annotations

Ontology Information

PRO ID

PR:000035703 Show OBO stanza / PAF / GPI

PRO name

CD14 molecule isoform 1 cleaved 2 soluble form (human)

Synonyms

Definition

A CD14 molecule isoform 1 cleaved 2 soluble form in human. UniProtKB:P08571-1, 20-345. [PRO:DNx, UniProtKB:P08571]

PRO Category

organism-modification

Parent

PR:000002147 CD14 molecule isoform 1 cleaved 2 soluble form

Taxon

Term Hierarchy Visualization

DAG

OLS

Related Cross References
DB identifiers	Reactome:R-HSA-166025

Interactive Sequence View Select/align proteoforms across species

Protein Forms

PRO ID & Category Annotation Complex	Name	Short Label	Definition & Comment

hCD14/iso:1/Clv:2/soluble forms found in complexes

hCD14/iso:1/Clv:2/soluble Component	Complexes
PR:000035703 hCD14/iso:1/Clv:2/soluble	PR:000037479 lipopolysaccharide receptor complex 4 (human)
PR:000035703 hCD14/iso:1/Clv:2/soluble	PR:000037463 LPS:secreted CD14 alpha (human)

Functional Annotation

PRO Term	GO Annotation		Evidence
PR:000035703 hCD14/iso:1/Clv:2/soluble	acts_upstream_of_or_within	GO:0034142 toll-like receptor 4 signaling pathway	Reactome:REACT_6894
	enables	GO:0001530 lipopolysaccharide binding	PMID:9464818
	expressed_in	CL:0000129 microglial cell	PMID:24659539
	located_in	GO:0005576 extracellular region	PMID:2779588, PMID:9665271

Cellular Location GO Term	Protein Forms & Complexes	Evidence
GO:0005576 extracellular region	PR:000035703 hCD14/iso:1/Clv:2/soluble	PMID:2779588, PMID:9665271

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