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Protein Ontology Report - hCD14/iso:1/Clv:2/soluble

PR:000035703 -
Ontology Information
PRO ID PR:000035703 Show OBO stanza / PAF / GPI
PRO name CD14 molecule isoform 1 cleaved 2 soluble form (human)
PRO-short-label: EXACT: hCD14/iso:1/Clv:2/soluble
PRO-proteoform-std: EXACT: UniProtKB:P08571-1, 20-345
PRO-proteoform-ftid: EXACT: PRO_0000020885
Other: EXACT: Secreted form of CD14 (human)
Definition A CD14 molecule isoform 1 cleaved 2 soluble form in human. UniProtKB:P08571-1, 20-345. [PRO:DNx, UniProtKB:P08571]
PRO Category organism-modification
Parent PR:000002147 CD14 molecule isoform 1 cleaved 2 soluble form
Taxon NCBITaxon:9606 Homo sapiens
Term Hierarchy Visualization DAG     OLS     Cytoscape

Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

hCD14/iso:1/Clv:2/soluble forms found in complexes
hCD14/iso:1/Clv:2/soluble Component Complexes
PR:000035703 hCD14/iso:1/Clv:2/soluble PR:000037479 lipopolysaccharide receptor complex 4 (human)
PR:000035703 hCD14/iso:1/Clv:2/soluble PR:000037463 LPS:secreted CD14 alpha (human)

Functional Annotation
PRO Term GO Annotation Evidence
acts_upstream_of_or_within GO:0034142 toll-like receptor 4 signaling pathway Reactome:REACT_6894
enables GO:0001530 lipopolysaccharide binding PMID:9464818
expressed_in CL:0000129 microglial cell PMID:24659539
located_in GO:0005576 extracellular region PMID:2779588, PMID:9665271
Cellular Location GO Term Protein Forms & Complexes Evidence
GO:0005576 extracellular region PR:000035703 hCD14/iso:1/Clv:2/soluble

PMID:2779588, PMID:9665271