PRO Entry Report - PR:000036004

Complex Forms Complex Subunits Annotations

Ontology Information

PRO ID

PR:000036004 Show OBO stanza / PAF / GPI

PRO name

LY96:TLR4 complex (human)

Synonyms

PRO-short-label:	EXACT:	h(LY96:TLR4)
Other:	EXACT:	MD2:TLR4 complex (human) \| TLR4MD2 complex (human)

Definition

An LY96:TLR4 complex whose components are encoded in the genome of human. [PMID:17803912, PMID:19252480, Reactome:R-HSA-166050]

Comment

Requested by=TLR.

PRO Category

organism-complex

Parent

PR:000036003 LY96:TLR4 complex

Taxon

Terms by PRO Category

Retrieve All terms OBO Stanza / PAF

Organism-Specific
Category	Number of Terms
organism-complex	1

Term Hierarchy Visualization

DAG

OLS

Related Cross References
DB identifiers	Reactome:R-HSA-166050

Complex Forms

PRO ID & Category Annotation Subunits	Name	Short Label	Definition & Comment

Complex Subunits

Complex	PRO ID	Name	Short Label	Definition	Number in Complex
PR:000036004	PR:000025786	lymphocyte antigen 96 isoform 1, signal peptide removed N-glycosylated 1 (human)	hLY96/iso:1/SigPep-/NGlyco:1	A lymphocyte antigen 96 isoform 1, signal peptide removed N-glycosylated 1 in human. UniProtKB:Q9Y6Y9-1, 19-160, Asn-26/Asn-114, MOD:00160. [PMID:11593030, PMID:11706042, PMID:17569869, TLR:AMM]
PR:000036004	PR:000025787	Toll-like receptor 4 isoform 1, signal peptide removed N-glycosylated 1 (human)	hTLR4/iso:1/SigPep-/NGlyco:1	A Toll-like receptor 4 isoform 1, signal peptide removed N-glycosylated 1 in human. UniProtKB:O00206-1, 24-839, Asn-35/Asn-173/Asn-205/Asn-282/Asn-309/Asn-497/Asn-526/Asn-575/Asn-624, MOD:00160. [PMID:11706042, PMID:19252480]

Functional Annotation

PRO Term	GO Annotation		Evidence
PR:000036004 LY96:TLR4 complex (human)	acts_upstream_of_or_within	GO:0034142 toll-like receptor 4 signaling pathway	Reactome:REACT_6894
PR:000036004 LY96:TLR4 complex (human)	located_in	GO:0005886 plasma membrane	Reactome:REACT_7105

Cellular Location GO Term	Protein Forms & Complexes	Evidence
GO:0005886 plasma membrane	PR:000036004 LY96:TLR4 complex (human)	Reactome:REACT_7105

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