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Protein Ontology Report - IRF3:XPO1 complex (human)

PR:000036045 - http://purl.obolibrary.org/obo/PR_000036045
Ontology Information
PRO ID PR:000036045 Show OBO stanza / PAF / GPI
PRO name IRF3:XPO1 complex (human)
Synonyms
Other: BROAD: IRF3pIRF3pIMP4alpha human | IRF3pIRF3pQip1 human
Definition An IRF3:XPO1 complex whose components are encoded in the genome of human. Exportin-1 recognizes the NES sequence (ILDELLGNMVL) and maintaints IRF-3 in the cytoplasm. [PMID:10805757, TLR:AMM]
Comment Requested by=TLR.
PRO Category organism-complex
Parent PR:000036044 IRF3:XPO1 complex
Taxon NCBITaxon:9606 Homo sapiens
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Specific
Category Number of Terms
organism-complex 1
Term Hierarchy Visualization DAG     OLS     Cytoscape

Complex Forms
PRO ID & Category Annotation Subunits Name Short Label Definition & Comment

Complex Subunits
Complex PRO ID Name Short Label Definition Number in Complex
PR:000036045 PR:Q14653 interferon regulatory factor 3 (human) hIRF3 An interferon regulatory factor 3 that is encoded in the genome of human. [PRO:CNA]
PR:O14980 exportin-1 (human) hXPO1 An exportin-1 that is encoded in the genome of human. [PRO:CNA]


Functional Annotation
PRO Term GO Annotation Evidence
PR:000036045
IRF3:XPO1 complex (human)
located_in GO:0005737 cytoplasm PMID:10805757
Cellular Location GO Term Protein Forms & Complexes Evidence
GO:0005737 cytoplasm PR:000036045 IRF3:XPO1 complex (human)

PMID:10805757

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