PRO Entry Report - PR:000036096

Protein Ontology Report - tbk1:K63-poly-Ub-tank:traf3:ticam1:ticam2:activated TLR4 complex

PR:000036096 - http://purl.obolibrary.org/obo/PR_000036096

Complex Forms Complex Subunits

Ontology Information

PRO ID

PR:000036096 Show OBO stanza

PRO name

tbk1:K63-poly-Ub-tank:traf3:ticam1:ticam2:activated TLR4 complex

Synonyms

Other:

BROAD:

K63-poly-Ub-tank:TRAF3:TRIF:TRAM:activated TLR4

Definition

A protein-containing complex that is composed of activated Toll-like receptor 4 (TLR4), TICAM2, TICAM1, TRAF3, TBK1 and TANK linked to Lys-63 polyubiquitin. [TLR:AMM]

Comment

Requested by=TLR.

PRO Category

complex

Parent

GO:0032991 protein-containing complex

Terms by PRO Category

Retrieve All terms OBO Stanza / PAF

Organism-Independent		Organism-Specific
Category	Number of Terms	Category	Number of Terms
complex	1	organism-complex	1

Term Hierarchy Visualization

DAG

OLS

Cytoscape

Complex Forms

PRO ID & Category Annotation Subunits	Name	Short Label	Definition & Comment

Complex Subunits

Complex	PRO ID	Name	Short Label	Definition
PR:000036097	PR:Q9WUN2	serine/threonine-protein kinase TBK1 (mouse)	mTBK1	A serine/threonine-protein kinase TBK1 that is encoded in the genome of mouse. [OMA:Q9WUN2, PRO:CNA]
	PR:Q60803	TNF receptor-associated factor 3 (mouse)	mTRAF3	A TNF receptor-associated factor 3 that is encoded in the genome of mouse. [OMA:Q60803, PRO:CNA]
	PR:Q8BJQ4	TIR domain-containing adapter molecule 2 (mouse)	mTICAM2	A TIR domain-containing adapter molecule 2 that is encoded in the genome of mouse. [OMA:Q8BJQ4, PRO:CNA]
	PR:Q80UF7	TIR domain-containing adapter molecule 1 (mouse)	mTICAM1	A TIR domain-containing adapter molecule 1 that is encoded in the genome of mouse. [OMA:Q80UF7, PRO:CNA]
	PR:000027171	lymphocyte antigen 96 isoform 1, signal peptide removed N-glycosylated 1 (mouse)	mLY96/iso:1/SigPep-/NGlyco:1	A lymphocyte antigen 96 isoform 1, signal peptide removed glycosylated form in mouse that has been N-glycosylated on Asn residues at positions 26, 114, and 150 of the amino acid sequence represented by UniProtKB:Q9JHF9-1. UniProtKB:Q9JHF9-1, 19-160, Asn-26/Asn-114/Asn-150, MOD:00160. [PMID:17803912, PRO:CNA]
	PR:000027172	Toll-like receptor 4 isoform 1, signal peptide removed N-glycosylated 1 (mouse)	mTLR4/iso:1/SigPep-/NGlyco:1	A Toll-like receptor 4 isoform 1, signal peptide removed form in mouse that has been N-glycosylated on Asn residues at positions 34, 75, 172, 204, 237, 307, 492, 524 and 572 of the amino acid sequence represented by UniProtKB:Q9QUK6-1. UniProtKB:Q9QUK6-1, 26-835, Asn-34/Asn-75/Asn-172/Asn-204/Asn-237/Asn-307/Asn-492/Asn-524/Asn-572, MOD:00160. [PMID:17803912, PRO:CNA]
	PR:000036091	TRAF family member-associated NF-kappa-B activator isoform 1 K63-polyubiquitinated form (mouse)	mTANK/iso:1/K63polyUbiq+	A TRAF family member-associated NF-kappa-B activator isoform 1 K63-polyubiquitinated form in mouse. UniProtKB:P70347-1, PR:000044772. [TLR:AMM]
	CHEBI:16412	lipopolysaccharide	lipopolysaccharide	Natural compounds consisting of a trisaccharide repeating unit (two heptose units and octulosonic acid) with oligosaccharide side chains and 3-hydroxytetradecanoic acid units (they are a major constituent of the cell walls of Gram-negative bacteria). [fake:1]

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