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Protein Ontology Report - mTBK1

This page represents a class of proteins encompassing all the protein products of the Tbk1 gene in Mus musculus.
Ontology Information
PRO ID PR:Q9WUN2 Show OBO stanza / PAF / GPI
PRO name serine/threonine-protein kinase TBK1 (mouse)
PRO-short-label: EXACT: mTBK1
Gene-based: RELATED: Tbk1
Other: EXACT: NAK (mouse) | NF-kappa-B-activating kinase (mouse) | T2K (mouse) | TANK-binding kinase 1 (mouse)
Definition A serine/threonine-protein kinase TBK1 that is encoded in the genome of mouse. [OMA:Q9WUN2, PRO:CNA]
Comment Requested by=TLR.
PRO Category organism-gene
Parent PR:000001779 serine/threonine-protein kinase TBK1
Gene Template MGI:1929658 Tbk1
Taxon NCBITaxon:10090 Mus musculus
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Category Number of Terms
organism-gene 1
organism-sequence 0
organism-modification 0
Term Hierarchy Visualization DAG     OLS     Cytoscape

Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

mTBK1 forms found in complexes
mTBK1 Component Complexes
PR:Q9WUN2 mTBK1 PR:000037313 tbk1:tank:ikke:traf3:ticam1:activated TLR3 complex (mouse)
PR:Q9WUN2 mTBK1 PR:000036097 tbk1:K63-poly-Ub-tank:traf3:ticam1:ticam2:activated TLR4 complex (mouse)
PR:Q9WUN2 mTBK1 PR:000036149 tbk1:tank:ikke complex (mouse)
PR:Q9WUN2 mTBK1 PR:000036090 tbk1:tank:ikke:traf3:ticam1:ticam2:activated TLR4 complex (mouse)
PR:Q9WUN2 mTBK1 PR:000036093 tbk1:K63-poly-Ub-tank:Ikke:traf3:ticam1:ticam2:activated TLR4 complex (mouse)

Functional Annotation
PRO Term GO Annotation Evidence
tbk1:tank:ikke complex (mouse)
acts_upstream_of_or_within GO:0034138 toll-like receptor 3 signaling pathway PMID:17823124
tbk1:tank:ikke:traf3:ticam1:activated TLR3 complex (mouse)
acts_upstream_of_or_within GO:0034138 toll-like receptor 3 signaling pathway PMID:12133833, PMID:17327220