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Protein Ontology Report - viral dsRNA:TLR3 complex (chicken)

PR:000037461 - http://purl.obolibrary.org/obo/PR_000037461
Ontology Information
PRO ID PR:000037461 Show OBO stanza / PAF / GPI
PRO name viral dsRNA:TLR3 complex (chicken)
Definition A viral dsRNA:TLR3 complex whose components are encoded in the genome of chicken. [PMID:17316136, PMID:18420935, PRO:VS, Reactome:R-GGA-433883]
Comment Requested by=TLR. Note: Viral dsRNA triggers an antiviral pathway mediated by Toll-like receptor 3. TLR3 dimerization occurs upon ligand binding to positivly charged residues on the ectodomain termini of TLR3 wich are responsible for the interaction with sugar-phosphate groups of dsRNA.
PRO Category organism-complex
Parent PR:000037302 viral dsRNA:TLR3 complex
Taxon NCBITaxon:9031 Gallus gallus
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Specific
Category Number of Terms
organism-complex 1
Term Hierarchy Visualization DAG     OLS     Cytoscape


Complex Forms
PRO ID & Category Annotation Subunits Name Short Label Definition & Comment

Complex Subunits
Complex PRO ID Name Short Label Definition Number in Complex
PR:000037461 PR:Q0PQ88 Toll-like receptor 3 (chicken) chick-TLR3 A Toll-like receptor 3 that is encoded in the genome of chicken. [PRO:CNA] 2
CHEBI:67208 dsRNA dsRNA A double stranded ribonucleic acid. [None] 1


Functional Annotation
PRO Term GO Annotation Evidence
PR:000037461
viral dsRNA:TLR3 complex (chicken)
acts_upstream_of_or_within GO:0034138 toll-like receptor 3 signaling pathway Reactome:REACT_24923
located_in GO:0010008 endosome membrane Reactome:REACT_24923
Cellular Location GO Term Protein Forms & Complexes Evidence
GO:0010008 endosome membrane PR:000037461 viral dsRNA:TLR3 complex (chicken)

Reactome:REACT_24923

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