back to PRO homepage
  Home |   Linked Open Data |   Browse |   Search |   Statistics |   Download
 RACE-PRO
 PRO tracker
 Community
 PRO Consortium
 Publications
 Documentation

Protein Ontology Report - hYAP1/Phos:1

PR:000037510 - http://purl.obolibrary.org/obo/PR_000037510
Ontology Information
PRO ID PR:000037510 Show OBO stanza / PAF / GPI
PRO name transcriptional coactivator YAP1 phosphorylated 1 (human)
Synonyms
PRO-short-label: EXACT: hYAP1/Phos:1
PRO-proteoform-std: NARROW: UniProtKB:P46937-1, Ser-127, MOD:00046
Other: EXACT: hYap1 Ser127
Definition A transcriptional coactivator YAP1 (human) that has been phosphorylated on the residue at the position equivalent to Ser-127 of the amino acid sequence represented by UniProtKB:P46937-1. Example: UniProtKB:P46937-1, Ser-127, MOD:00046. [PMID:20153295, PMID:21214929, PMID:21945154, PRO:KER]
Comment Kinase=("AKT"; PR:000029189; Ser-127). Kinase=("PKC"; PR:000003057; Ser-127).Note: Isoform PR:P46937-4 is excluded from this class as it lacks the region containing the corresponding Ser (isoform 4 lacks the N-terminal region of 178 residues compared to isoform 1).
PRO Category organism-modification
Parent PR:P46937 transcriptional coactivator YAP1 (human)
Taxon NCBITaxon:9606 Homo sapiens
Term Hierarchy Visualization DAG     OLS     Cytoscape


Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:000037510
hYAP1/Phos:1
Ser-127, MOD:00046
associated_with_disease_progression DOID:162 cancer PMID:21214929
associated_with_disease_suppression DOID:10652 Alzheimer's disease PMID:21945154
enables GO:0005515 protein binding with PR:000003237 fam:14-3-3 PMID:21214929
enables GO:0005515 protein binding decreased relative to PR:000037509 hYAP1/UnPhos:1 with PR:O15350 hTP73 PMID:21945154

top