| PRO ID |
PR:000045489
Show OBO stanza
/ GPI
|
| PRO name |
interferon regulatory factor 3 isoform 1 phosphorylated 2 (human) |
| Synonyms |
| PRO-short-label: |
EXACT: |
hIRF3/iso:1/Phos:2 |
| PRO-proteoform-std: |
EXACT: |
UniProtKB:Q14653-1, Ser-339/Ser-386/Ser-398/Ser-402/Ser-405, MOD:00046|Thr-404, MOD:00047 |
| Other: |
RELATED: |
p-5S,T404-IRF3 (human) |
|
| Definition |
An interferon regulatory factor 3 isoform 1 (human) that has been phosphorylated in Ser-339 and Ser and Thr residues within the two phosphorylation cluster sites. A Ser-386 on the 2S site and multiple Ser and Thr residues in the 5ST site (Ser-396, Ser-498, Ser-402, Thr-404, and Ser-405). UniProtKB:Q14653-1, Ser-339/Ser-386/Ser-398/Ser-402/Ser-405, MOD:00046, Thr-404, MOD:00047.
[PRO:CNA, Reactome:R-HSA-936418]
|
| Comment |
Note: Reactome does not specify the precise isoform. However, it mentions that this proteoform is involved in dimerization. Based on the positions of the modified residues, and based on the position of the dimerization domain (203-385), only isoform 1 is eligible. [PRO:DAN, PMID:23824805] |
| PRO Category |
organism-modification |
| Parent |
PR:Q14653-1 interferon regulatory factor 3 isoform 1 (human) |
| Taxon |
NCBITaxon:9606 Homo sapiens |
| Term Hierarchy Visualization |
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