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Protein Ontology Report - hIgA1

PR:000050157 -
Ontology Information
PRO ID PR:000050157 Show OBO stanza / GPI
PRO name IgA1 immunoglobulin complex (human)
PRO-short-label: EXACT: hIgA1
Other: NARROW: IgA1 antibody (human)
BROAD: IgA antibody (human)
Definition An IgA immunoglobulin complex that in monomeric form is composed of two identical immunoglobulin heavy chains of the IgA1 isotype and two identical immunoglobulin light chains (kappa or lambda) held together by disulfide bonds, and sometimes complexed with J chain or J chain and secretory component. An IgA1 immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph. [GOC:add, ISBN:0781765196, PMID:16362985, PRO:ADD]
Comment Requested by=HIPC. Requested by=CL. Note that an IgA1 immunoglobulin complex has the function of antigen binding if a suitable antigen is available.
PRO Category organism-complex
Parent GO:0071745 IgA immunoglobulin complex
Taxon NCBITaxon:9606 Homo sapiens
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Category Number of Terms
organism-complex 1
Term Hierarchy Visualization DAG     OLS     Cytoscape

Complex Forms
PRO ID & Category Annotation Subunits Name Short Label Definition & Comment

Complex Subunits
Complex PRO ID Name Short Label Definition Number in Complex
PR:000050157 PR:000050183 immunoglobulin light chain protein (human) hIgL An immunoglobulin light chain protein that is encoded in the genome of human. [PRO:DAN] 2
PR:000050179 IgA1 heavy chain protein (human) hIgHA1 An IgA1 heavy chain protein that is encoded in the genome of human. [PRO:DAN] 2