Protein Ontology Report - hEZR PR:P15311 - http://purl.obolibrary.org/obo/PR_P15311

This page represents a class of proteins encompassing all the protein products of the EZR gene in Homo sapiens.

Ontology Information
PRO ID	PR:P15311 Show OBO stanza / PAF / GPI
PRO name	ezrin (human)
Synonyms	PRO-short-label: EXACT: hEZR Gene-based: RELATED: EZR | VIL2 Other: EXACT: cytovillin (human) | villin-2 (human) BROAD: p81 (human)
Definition	An ezrin that is encoded in the genome of human. [PRO:CNA, UniProtKB:P15311]
PRO Category	organism-gene
Parent	PR:000001031 ezrin
Gene Template	HGNC:12691 EZR
Taxon	NCBITaxon:9606 Homo sapiens
Terms by PRO Category	Retrieve All terms OBO Stanza / PAF Organism-Specific Category Number of Terms organism-gene 1 organism-sequence 1 organism-modification 8
Term Hierarchy Visualization	DAG     OLS     Cytoscape

Related Cross References
DB identifiers	Reactome:R-HSA-9020826, UniProtKB:P15311

Interactive Sequence View Select/align proteoforms across species

Protein Forms Display Category: All All organism-gene organism-sequence organism-modification
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation PRO Centric View GO Centric View

PRO Term GO Annotation Evidence PR:000036589 hEZR/iso:1/Phos:2 Ser-66, MOD:00046 enables GO:0005515 protein binding with PR:000002696 WWOX/iso:1/UnMod PMID:16438931 PR:000036590 hEZR/iso:1/Phos:3 Tyr-191, MOD:00048 enables GO:0005515 protein binding with PR:P00523-1 chick-SRC/iso:1 PMID:15647376 PR:000036625 hEZR/iso:1/Phos:6 Tyr-354, MOD:00048|Thr-567, MOD:00047 enables GO:0003779 actin binding PMID:18852256 located_in GO:0005886 plasma membrane PMID:18852256 located_in GO:0002102 podosome PMID:18852256 PR:000036592 hEZR/iso:1/Phos:5 Thr-567, MOD:00047 acts_upstream_of_or_within GO:0001771 immunological synapse formation PMID:18025306 acts_upstream_of_or_within GO:0051279 regulation of release of sequestered calcium ion into cytosol PMID:18025306 enables GO:0005515 protein binding with PR:P43403 hZAP70 PMID:18025306 located_in GO:0045177 apical part of cell PMID:16144865 located_in GO:0001772 immunological synapse PMID:18025306 Cellular Location GO Term Protein Forms & Complexes Evidence GO:0002102 podosome PR:000036625 hEZR/iso:1/Phos:6 Tyr-354, MOD:00048|Thr-567, MOD:00047 PMID:18852256 GO:0045177 apical part of cell PR:000036592 hEZR/iso:1/Phos:5 Thr-567, MOD:00047 PMID:16144865 GO:0005886 plasma membrane PR:000036625 hEZR/iso:1/Phos:6 Tyr-354, MOD:00048|Thr-567, MOD:00047 PMID:18852256 GO:0001772 immunological synapse PR:000036592 hEZR/iso:1/Phos:5 Thr-567, MOD:00047 PMID:18025306

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