PRO Entry Report - PR:P47757-2

Protein Forms Complex Annotations

Ontology Information

PRO ID

PR:P47757-2 Show OBO stanza / PAF / GPI

PRO name

F-actin-capping protein subunit beta isoform 2 (mouse)

Synonyms

PRO-short-label:	EXACT:	mCAPZB/iso:2
Other:	EXACT:	CAPZ beta 2 (mouse) \| CAPZ beta-2 (mouse) \| CAPZB2 (mouse)

Definition

An F-actin-capping protein subunit beta isoform 2 that is encoded in the genome of mouse. [PMID:10601341, PRO:KRC]

PRO Category

organism-sequence

Parent

PR:000035826 F-actin-capping protein subunit beta isoform 2

Taxon

Term Hierarchy Visualization

DAG

OLS

Related Cross References
DB identifiers	UniProtKB:P47757-2

Interactive Sequence View Select/align proteoforms across species

Protein Forms

PRO ID & Category Annotation Complex	Name	Short Label	Definition & Comment

mCAPZB/iso:2 forms found in complexes

mCAPZB/iso:2 Component	Complexes
PR:P47757-2 mCAPZB/iso:2	PR:000035901 F-actin capping protein complex alpha-2 beta-2 (mouse)
PR:P47757-2 mCAPZB/iso:2	PR:000035900 F-actin capping protein complex alpha-1 beta-2 (mouse)

Functional Annotation

PRO Term	GO Annotation		Evidence
PR:P47757-2 mCAPZB/iso:2	acts_upstream_of_or_within	GO:0031115 negative regulation of microtubule polymerization	MGI:4397629, PMID:19806181
	acts_upstream_of_or_within	GO:0030032 lamellipodium assembly	MGI:4397629, PMID:19806181
	acts_upstream_of_or_within	GO:0051016 barbed-end actin filament capping	MGI:3758397, PMID:17656356
	acts_upstream_of_or_within	GO:0055001 muscle cell development	MGI:1350695, PMID:10601341
	acts_upstream_of_or_within	GO:0031175 neuron projection development	MGI:4397629, PMID:19806181
	enables	GO:0051015 actin filament binding	MGI:3758397, PMID:17656356
	enables	GO:0048487 beta-tubulin binding with PR:Q9ERD7 mTUBB3	MGI:4397629, PMID:19806181
	enables	GO:0005515 protein binding with PR:Q91YR1 mTWF1	MGI:3773286, PMID:11604420
	located_in	GO:0014704 intercalated disc	MGI:1350695, PMID:10601341
	located_in	GO:0014704 intercalated disc	MGI:68935, PMID:7929588
	part_of	GO:0008290 F-actin capping protein complex	MGI:3773286, PMID:11604420
	part_of	GO:0008290 F-actin capping protein complex with PR:P47754 mCAPZA2	MGI:4397629, PMID:19806181

Cellular Location GO Term	Protein Forms & Complexes	Evidence
GO:0014704 intercalated disc	PR:P47757-2 mCAPZB/iso:2	MGI:1350695, PMID:10601341
GO:0014704 intercalated disc	PR:P47757-2 mCAPZB/iso:2	MGI:68935, PMID:7929588

top