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Protein Ontology Report - mTRAF6

PR:P70196 - http://purl.obolibrary.org/obo/PR_P70196
This page represents a class of proteins encompassing all the protein products of the Traf6 gene in mouse.
Ontology Information
PRO ID PR:P70196 Show OBO stanza / PAF
PRO name TNF receptor-associated factor 6 (mouse)
Synonyms
PRO-short-label: EXACT: mTRAF6
Gene-based: RELATED: Traf6
Other: EXACT: E3 ubiquitin-protein ligase TRAF6 (mouse) | RING-type E3 ubiquitin transferase TRAF6 (mouse)
Definition A TNF receptor-associated factor 6 that is encoded in the genome of mouse. [OMA:P70196, PRO:CNA]
Comment Requested by=TLR.
PRO Category organism-gene
Parent PR:000002292 TNF receptor-associated factor 6
Gene Template MGI:108072 Traf6
Taxon NCBITaxon:10090 Mus musculus
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Specific
Category Number of Terms
organism-gene 1
organism-sequence 2
organism-modification 1
Term Hierarchy Visualization DAG     OLS     Cytoscape


Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

mTRAF6 forms found in complexes
mTRAF6 Component Complexes
PR:P70196 mTRAF6 PR:000035710 traf6:ticam1:ticam2:activated TLR4 complex (mouse)
PR:P70196 mTRAF6 PR:000036101 rip1:traf6:ticam1:ticam2:activated TLR4 complex (mouse)
PR:P70196 mTRAF6 PR:000036105 pel1:rip1:traf6:ticam1:ticam2:activated TLR4 complex (mouse)
PR:P70196 mTRAF6 PR:000037471 traf6:ticam1:activated TLR3 complex (mouse)
PR:P70196 mTRAF6 PR:000036111 K63-poly-Ub-rip1:traf6:TAK1 kinase complex (mouse)
PR:P70196 mTRAF6 PR:000036114 IkappaB kinase:K63-poly-Ub-rip1:traf6:TAK1 kinase complex (mouse)
PR:P70196 mTRAF6 PR:000036117 pIKBK:K63-poly-Ub-rip1:traf6:TAK1 kinase complex (mouse)
PR:P70196 mTRAF6 PR:000036109 pel1:K63-poly-Ub-rip1:traf6:ticam1:ticam2:activated TLR4 complex (mouse)

Functional Annotation
PRO Term GO Annotation Evidence
PR:000035710
traf6:ticam1:ticam2:activated TLR4 complex (mouse)
participates_in GO:0002756 MyD88-independent toll-like receptor signaling pathway PMID:14530355
PR:000036101
rip1:traf6:ticam1:ticam2:activated TLR4 complex (mouse)
participates_in GO:0002756 MyD88-independent toll-like receptor signaling pathway Reactome:REACT_6809
Biological Process GO Term Protein Forms & Complexes Evidence
GO:0002756 MyD88-independent toll-like receptor signaling pathway PR:000035710 traf6:ticam1:ticam2:activated TLR4 complex (mouse)

PMID:14530355
PR:000036101 rip1:traf6:ticam1:ticam2:activated TLR4 complex (mouse)

Reactome:REACT_6809

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