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Protein Ontology Report - hINCENP

PR:Q9NQS7 - http://purl.obolibrary.org/obo/PR_Q9NQS7
This page represents a class of proteins encompassing all the protein products of the INCENP gene in human.
Ontology Information
PRO ID PR:Q9NQS7 Show OBO stanza / PAF
PRO name inner centromere protein (human)
Synonyms
PRO-short-label: EXACT: hINCENP
Gene-based: RELATED: INCENP
Definition An inner centromere protein that is encoded in the genome of human. [PRO:KER]
PRO Category organism-gene
Parent PR:000009029 inner centromere protein
Gene Template HGNC:6058 INCENP
Taxon NCBITaxon:9606 Homo sapiens
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Specific
Category Number of Terms
organism-gene 1
organism-sequence 2
organism-modification 2
Term Hierarchy Visualization DAG     OLS     Cytoscape


Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:Q9NQS7
hINCENP
capable_of GO:0005515 protein binding with PR:P06493 hCDK1 IntAct:EBI-1397779
capable_of GO:0005515 protein binding with PR:O15392 hBIRC5 BioGRID:BG-592275, MINT:MINT-4509563
capable_of GO:0005515 protein binding with PR:Q96GD4 hAURKB BioGRID:BG-251075, IntAct:EBI-1555366, MINT:MINT-77928
capable_of GO:0005515 protein binding with PR:Q5FBB7 hSGO1 BioGRID:BG-300524
capable_of GO:0005515 protein binding with PR:Q71DI3 hH3.2 BioGRID:BG-725716
capable_of GO:0005515 protein binding with PR:Q53HL2 hCDCA8 BioGRID:BG-463513, IntAct:EBI-1555222
located_in GO:0000776 kinetochore PMID:20624902
located_in GO:0000939 inner kinetochore PMID:16760428
participates_in GO:0034501 protein localization to kinetochore PMID:17617734
participates_in GO:0034501 protein localization to kinetochore PMID:16760428
PR:000035527
hINCENP/Phos:1
Thr-892, MOD:00047|Ser-893/Ser-894, MOD:00046 		participates_in GO:0033674 positive regulation of kinase activity increased relative to PR:000035529 hINCENP/PhosRes- PMID:22024163
Molecular Function GO Term Protein Forms & Complexes Evidence
GO:0005515 protein binding PR:Q9NQS7 hINCENP

with PR:P06493 hCDK1 		IntAct:EBI-1397779
PR:Q9NQS7 hINCENP

with PR:O15392 hBIRC5 		BioGRID:BG-592275, MINT:MINT-4509563
PR:Q9NQS7 hINCENP

with PR:Q96GD4 hAURKB 		BioGRID:BG-251075, IntAct:EBI-1555366, MINT:MINT-77928
PR:Q9NQS7 hINCENP

with PR:Q5FBB7 hSGO1 		BioGRID:BG-300524
PR:Q9NQS7 hINCENP

with PR:Q71DI3 hH3.2 		BioGRID:BG-725716
PR:Q9NQS7 hINCENP

with PR:Q53HL2 hCDCA8 		BioGRID:BG-463513, IntAct:EBI-1555222
Biological Process GO Term Protein Forms & Complexes Evidence
GO:0033674 positive regulation of kinase activity PR:000035527 hINCENP/Phos:1
Thr-892, MOD:00047|Ser-893/Ser-894, MOD:00046
increased relative to PR:000035529 hINCENP/PhosRes- 		PMID:22024163
GO:0034501 protein localization to kinetochore PR:Q9NQS7 hINCENP

PMID:17617734
PR:Q9NQS7 hINCENP

PMID:16760428
Cellular Location GO Term Protein Forms & Complexes Evidence
GO:0000939 inner kinetochore PR:Q9NQS7 hINCENP

PMID:16760428
GO:0000776 kinetochore PR:Q9NQS7 hINCENP

PMID:20624902

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