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Protein Ontology Report - Trpc2

PR:000001725 - http://purl.obolibrary.org/obo/PR_000001725
Ontology Information
PRO ID PR:000001725 Show OBO stanza / PAF
PRO name short transient receptor potential cation channel TRPC2
Synonyms
PRO-short-label: EXACT: Trpc2
Gene-based: RELATED: Trp2 | Trrp2
Other: EXACT: TrpC2 | transient receptor protein 2
RELATED: TRP-2
Definition A transient receptor potential cation channel TRPC that is a translation product of the mouse Trpc2 gene or a 1:1 ortholog thereof. It mediates both receptor- and store depletion-triggered calcium entry. It plays an important role in the transduction machinery underlying the detection of pheromone signals by the vomeronasal organ (VNO), a part of the accessory olfactory system. [PMID:15971083, PMID:17217050]
PRO Category gene
Parent PR:000000680 transient receptor potential cation channel TRPC
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Independent Organism-Specific
Category Number of Terms Category Number of Terms
gene 1 organism-gene 1
sequence 4 organism-sequence 4
modification 0 organism-modification 0
union 0
Term Hierarchy Visualization DAG     OLS     Cytoscape


Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:Q9R244-2
mTrpc2/iso:2
enables GO:0005516 calmodulin binding PMID:12601176
PR:Q9R244-3
mTrpc2/iso:3
located_in GO:0005635 nuclear envelope MGI:1913270, PMID:10998353
located_in GO:0005789 endoplasmic reticulum membrane MGI:1913270, PMID:10998353
located_in GO:0000139 Golgi membrane MGI:1913270, PMID:10998353
PR:Q9R244
mTrpc2
acts_upstream_of_or_within NOT GO:0015279 store-operated calcium channel activity PMID:10998353
PR:Q9R244-4
mTrpc2/iso:4
located_in GO:0000139 Golgi membrane PMID:10998353
located_in GO:0005789 endoplasmic reticulum membrane MGI:1913270, PMID:10998353
located_in GO:0005635 nuclear envelope MGI:1913270, PMID:10998353
PR:Q9R244-1
mTrpc2/iso:1
enables GO:0005516 calmodulin binding MGI:2652910, PMID:12601176
Cellular Location GO Term Protein Forms & Complexes Evidence
GO:0005635 nuclear envelope PR:Q9R244-3 mTrpc2/iso:3

MGI:1913270, PMID:10998353
PR:Q9R244-4 mTrpc2/iso:4

MGI:1913270, PMID:10998353
GO:0005789 endoplasmic reticulum membrane PR:Q9R244-3 mTrpc2/iso:3

MGI:1913270, PMID:10998353
PR:Q9R244-4 mTrpc2/iso:4

MGI:1913270, PMID:10998353
GO:0000139 Golgi membrane PR:Q9R244-3 mTrpc2/iso:3

MGI:1913270, PMID:10998353
PR:Q9R244-4 mTrpc2/iso:4

PMID:10998353

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