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Protein Ontology report - tyrosine-protein kinase Lck (human)
PR:P06239 - http://purl.obolibrary.org/obo/PR_P06239
 
  Protein Forms  Complex  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:P06239   
  PRO nametyrosine-protein kinase Lck (human) 
  Synonyms
PRO-Short-label: EXACT:hLCK
Gene-based: RELATED:LCK
Other: EXACT:leukocyte C-terminal Src kinase (human) | LSK (human) | lymphocyte cell-specific protein-tyrosine kinase (human) | p56-LCK (human) | protein YT16 (human) | proto-oncogene Lck (human) | T cell-specific protein-tyrosine kinase (human)
  Definition"A tyrosine-protein kinase Lck that is encoded in the genome of human." [PRO:DNx] 
  PRO Categoryorganism-gene 
  ParentPR:000002998 tyrosine-protein kinase Lck
PR:000029067 Homo sapiens protein
  Gene TemplateHGNC:6524 LCK (human)
  TaxonNCBITaxon:9606 Homo sapiens
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene0                                                  Organism-Gene 1                                        
         Sequence0                                                  Organism-Sequence 3                                        
         Modification0                                                  Organism-Modification 4                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:P06239
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

Comp. In Complex?
organism-gene


PR:P06239 tyrosine-protein kinase Lck (human)
hLCK

Yes
organism-sequence


PR:P06239-1 tyrosine-protein kinase Lck isoform Long (human)
hLCK/iso:Long

organism-modification


PR:000036619 tyrosine-protein kinase Lck isoform 1 phosphorylated 1 (human)
hLCK/iso:1/Phos:1
Yes
organism-modification


PR:000036622 tyrosine-protein kinase Lck isoform 1 phosphorylated 2 (human)
hLCK/iso:1/Phos:2
Yes
organism-sequence


PR:P06239-2 tyrosine-protein kinase Lck isoform Short (human)
hLCK/iso:Short

organism-sequence


PR:P06239-3 tyrosine-protein kinase Lck isoform h3 (human)
hLCK/iso:h3

organism-modification


PR:000048171 tyrosine-protein kinase Lck phosphorylated 2 (human)
hLCK/Phos:2

organism-modification


PR:000048172 tyrosine-protein kinase Lck phosphorylated 3 (human)
hLCK/Phos:3

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hLCK forms found in complexes   

hLCK Component
 Complexes
PR:P06239 hLCK PR:000028449 CD4:Lck complex (human)
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000036619 hLCK/iso:1/Phos:1
UniProtKB:P06239-1, Tyr-394/Tyr-505, MOD:00048		 enablesdecreased GO:0016301 kinase activity relative to PR:000036622 hLCK/iso:1/Phos:2 PMID:9043947
PR:000036622 hLCK/iso:1/Phos:2
UniProtKB:P06239-1, Tyr-394, MOD:00048		 enablesGO:0016301 kinase activity PMID:9043947
GO:0044877 protein-containing complex binding PMID:9043947