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Protein Ontology report - tyrosine-protein kinase Lck (human)
PR:P06239 -
http://purl.obolibrary.org/obo/PR_P06239
Protein Forms
Complex
Annotations
Ontology Information
Show OBO stanza
/
GPI
PRO ID
PR:P06239
PRO name
tyrosine-protein kinase Lck (human)
Synonyms
PRO-Short-label
:
EXACT:
hLCK
Gene-based
:
RELATED:
LCK
Other
:
EXACT:
leukocyte C-terminal Src kinase (human) | LSK (human) | lymphocyte cell-specific protein-tyrosine kinase (human) | p56-LCK (human) | protein YT16 (human) | proto-oncogene Lck (human) | T cell-specific protein-tyrosine kinase (human)
Definition
"A tyrosine-protein kinase Lck that is encoded in the genome of human." [PRO:DNx]
PRO Category
organism-gene
Parent
PR:000002998
tyrosine-protein kinase Lck
PR:000029067
Homo sapiens protein
Gene Template
HGNC:6524
LCK (human)
Taxon
NCBITaxon:9606
Homo sapiens
Terms by PRO Category
Organism-Independent
Organism-Specific
Category
Number of Terms
Category
Number of Terms
Gene
0
Organism-Gene
1
Sequence
0
Organism-Sequence
3
Modification
0
Organism-Modification
4
Term Hierarchy
Visualization
DAG:
OLS:
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Related Cross References
Db identifiers
UniProtKB:P06239
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Protein Forms
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Extended View
Category
PRO Form Name
Ann.
Has Annotation?
Comp.
In Complex?
organism-gene
PR:P06239
tyrosine-protein kinase Lck (human), hLCK
Yes
organism-sequence
PR:P06239-1
tyrosine-protein kinase Lck isoform Long (human), hLCK/iso:Long
organism-modification
PR:000036619
tyrosine-protein kinase Lck isoform 1 phosphorylated 1 (human), hLCK/iso:1/Phos:1
Yes
organism-modification
PR:000036622
tyrosine-protein kinase Lck isoform 1 phosphorylated 2 (human), hLCK/iso:1/Phos:2
Yes
organism-sequence
PR:P06239-2
tyrosine-protein kinase Lck isoform Short (human), hLCK/iso:Short
organism-sequence
PR:P06239-3
tyrosine-protein kinase Lck isoform h3 (human), hLCK/iso:h3
organism-modification
PR:000048171
tyrosine-protein kinase Lck phosphorylated 2 (human), hLCK/Phos:2
organism-modification
PR:000048172
tyrosine-protein kinase Lck phosphorylated 3 (human), hLCK/Phos:3
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hLCK
forms found in complexes
hLCK
Component
Complexes
PR:P06239
hLCK
PR:000028449
CD4:Lck complex (human)
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Functional Annotation (PRO-centric view)
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GO Centric View
PRO Term
GO Annotation
Evidence
PR:000036619
hLCK/iso:1/Phos:1
UniProtKB:P06239-1, Tyr-394/Tyr-505, MOD:00048
"A tyrosine-protein kinase Lck isoform 1 phosphorylated 1 in human. UniProtKB:P06239-1, Tyr-394/Tyr-505, MOD:00048." [PMID:9043947, PRO:CL]
enables
decreased
GO:0016301
kinase activity
relative to
PR:000036622
hLCK/iso:1/Phos:2
PMID:9043947
PR:000036622
hLCK/iso:1/Phos:2
UniProtKB:P06239-1, Tyr-394, MOD:00048
"A tyrosine-protein kinase Lck isoform 1 phosphorylated 2 in human. UniProtKB:P06239-1, Tyr-394, MOD:00048." [PMID:9043947, PRO:CL]
enables
GO:0016301
kinase activity
PMID:9043947
GO:0044877
protein-containing complex binding
PMID:9043947