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gene
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PR:000000128 |
smad4
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SMAD4
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"A smad protein that is a translation product of the human SMAD4 gene or a 1:1 ortholog thereof. It lacks the C-terminal SSxS motif, necessary for receptor mediated phosphorylation, that is present in the receptor-regulated smads." [PMID:10708949, PRO:CNA]
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organism-gene
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PR:O70437 |
mothers against decapentaplegic homolog 4 (rat)
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rSMAD4
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"A smad4 that is encoded in the genome of rat." [OMA:O70437, PRO:DNx]
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organism-gene
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PR:P97471 |
mothers against decapentaplegic homolog 4 (mouse)
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mSMAD4
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"A smad4 that is encoded in the genome of mouse." [OMA:P97471, PRO:DNx]
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organism-sequence
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PR:P97471-1 |
mothers against decapentaplegic homolog 4 isoform 1 (mouse)
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mSMAD4/iso:1
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"A smad4 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]
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Yes |
Yes |
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organism-gene
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PR:Q13485 |
mothers against decapentaplegic homolog 4 (human)
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hSMAD4
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"A smad4 that is encoded in the genome of human." [PRO:CNA, UniProtKB:Q13485]
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Yes |
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organism-sequence
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PR:000000367 |
smad4 sequence variant E330G (human)
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hSMAD4/var:E330G
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"A mothers against decapentaplegic homolog 4 (human) that has a Gly residue at the position equivalent to Glu-330 of the amino acid sequence represented by UniProtKB:Q13485. UniProtKB:Q13485, Glu-330, CHEBI:29947." [PMID:12417513, PRO:CNA, PRO:DAN]
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Yes |
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organism-sequence
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PR:000000368 |
smad4 sequence variant G352R (human)
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hSMAD4/var:G352R
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"A mothers against decapentaplegic homolog 4 (human) that has an Arg residue at the position equivalent to Gly-352 of the amino acid sequence represented by UniProtKB:Q13485. UniProtKB:Q13485, Gly-352, CHEBI:29952." [PMID:12417513, PRO:CNA, PRO:DAN]
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Yes |
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organism-sequence
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PR:000000369 |
smad4 sequence variant R361C (human)
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hSMAD4/var:R361C
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"A mothers against decapentaplegic homolog 4 (human) that has a Cys residue at the position equivalent to Arg-361 of the amino acid sequence represented by UniProtKB:Q13485. UniProtKB:Q13485, Arg-361, CHEBI:29950." [PMID:9811934, PRO:CNA, PRO:DAN]
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Yes |
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organism-sequence
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PR:000000370 |
smad4 sequence variant G386D (human)
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hSMAD4/var:G386D
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"A mothers against decapentaplegic homolog 4 (human) that has an Asp residue at the position equivalent to Gly-386 of the amino acid sequence represented by UniProtKB:Q13485. UniProtKB:Q13485, Gly-386, CHEBI:29958." [PMID:15031030, PRO:CNA, PRO:DAN]
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Yes |
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organism-sequence
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PR:000000371 |
smad4 sequence variant D493H (human)
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hSMAD4/var:D493H
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"A mothers against decapentaplegic homolog 4 (human) that has a His residue at the position equivalent to Asp-493 of the amino acid sequence represented by UniProtKB:Q13485. UniProtKB:Q13485, Asp-493, CHEBI:29979." [PMID:8553070, PRO:CNA, PRO:DAN]
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Yes |
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organism-sequence
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PR:000060297 |
mothers against decapentaplegic homolog 4 sequence variant E538* (human)
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hSMAD4/var:E538*
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"A mothers against decapentaplegic homolog 4 (human) that has has been truncated after the position equivalent to Asp-537 of the amino acid sequence represented by UniProtKB:Q13485. UniProtKB:Q13485, 1-537." [PRO:DNx, Reactome:R-HSA-9675626]
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organism-sequence
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PR:000060358 |
mothers against decapentaplegic homolog 4 sequence variant D351G (human)
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hSMAD4/var:D351G
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"A mothers against decapentaplegic homolog 4 (human) that has a Gly residue at the position equivalent to Asp-351 of the amino acid sequence represented by UniProtKB:Q13485. UniProtKB:Q13485, Asp-351, CHEBI:29947." [PRO:DNx, Reactome:R-HSA-3310967]
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organism-sequence
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PR:000060432 |
mothers against decapentaplegic homolog 4 sequence variant G30* (human)
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hSMAD4/var:G30*
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"A mothers against decapentaplegic homolog 4 (human) that has has been truncated after the position equivalent to Gly-29 of the amino acid sequence represented by UniProtKB:Q13485. UniProtKB:Q13485, 1-29." [PRO:DNx, Reactome:R-HSA-9678450]
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organism-sequence
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PR:000060505 |
mothers against decapentaplegic homolog 4 sequence variant R445* (human)
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hSMAD4/var:R445*
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"A mothers against decapentaplegic homolog 4 (human) that has has been truncated after the position equivalent to His-444 of the amino acid sequence represented by UniProtKB:Q13485. UniProtKB:Q13485, 1-444." [PRO:DNx, Reactome:R-HSA-9675065]
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organism-sequence
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PR:000060581 |
mothers against decapentaplegic homolog 4 sequence variant E390* (human)
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hSMAD4/var:E390*
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"A mothers against decapentaplegic homolog 4 (human) that has has been truncated after the position equivalent to Leu-389 of the amino acid sequence represented by UniProtKB:Q13485. UniProtKB:Q13485, 1-389." [PRO:DNx, Reactome:R-HSA-9675620]
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organism-sequence
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PR:000060584 |
mothers against decapentaplegic homolog 4 sequence variant G358* (human)
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hSMAD4/var:G358*
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"A mothers against decapentaplegic homolog 4 (human) that has has been truncated after the position equivalent to Ser-357 of the amino acid sequence represented by UniProtKB:Q13485. UniProtKB:Q13485, 1-357." [PRO:DNx, Reactome:R-HSA-9678453]
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organism-sequence
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PR:000060627 |
mothers against decapentaplegic homolog 4 sequence variant Q410* (human)
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hSMAD4/var:Q410*
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"A mothers against decapentaplegic homolog 4 (human) that has has been truncated after the position equivalent to Val-409 of the amino acid sequence represented by UniProtKB:Q13485. UniProtKB:Q13485, 1-409." [PRO:DNx, Reactome:R-HSA-9675196]
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organism-sequence
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PR:000060690 |
mothers against decapentaplegic homolog 4 sequence variant D351H (human)
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hSMAD4/var:D351H
|
"A mothers against decapentaplegic homolog 4 (human) that has a His residue at the position equivalent to Asp-351 of the amino acid sequence represented by UniProtKB:Q13485. UniProtKB:Q13485, Asp-351, CHEBI:29979." [PRO:DNx, Reactome:R-HSA-3310965]
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organism-sequence
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PR:000060699 |
mothers against decapentaplegic homolog 4 sequence variant E526* (human)
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hSMAD4/var:E526*
|
"A mothers against decapentaplegic homolog 4 (human) that has has been truncated after the position equivalent to Ile-525 of the amino acid sequence represented by UniProtKB:Q13485. UniProtKB:Q13485, 1-525." [PRO:DNx, Reactome:R-HSA-9675648]
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organism-sequence
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PR:000060742 |
mothers against decapentaplegic homolog 4 sequence variant Q83* (human)
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hSMAD4/var:Q83*
|
"A mothers against decapentaplegic homolog 4 (human) that has has been truncated after the position equivalent to Leu-82 of the amino acid sequence represented by UniProtKB:Q13485. UniProtKB:Q13485, 1-82." [PRO:DNx, Reactome:R-HSA-9675199]
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organism-sequence
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PR:000060841 |
mothers against decapentaplegic homolog 4 sequence variant Y276* (human)
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hSMAD4/var:Y276*
|
"A mothers against decapentaplegic homolog 4 (human) that has has been truncated after the position equivalent to Pro-275 of the amino acid sequence represented by UniProtKB:Q13485. UniProtKB:Q13485, 1-275." [PRO:DNx, Reactome:R-HSA-9678466]
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organism-sequence
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PR:000060874 |
mothers against decapentaplegic homolog 4 sequence variant G473* (human)
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hSMAD4/var:G473*
|
"A mothers against decapentaplegic homolog 4 (human) that has has been truncated after the position equivalent to Pro-472 of the amino acid sequence represented by UniProtKB:Q13485. UniProtKB:Q13485, 1-472." [PRO:DNx, Reactome:R-HSA-9678440]
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organism-sequence
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PR:000060913 |
mothers against decapentaplegic homolog 4 sequence variant G477* (human)
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hSMAD4/var:G477*
|
"A mothers against decapentaplegic homolog 4 (human) that has has been truncated after the position equivalent to Gly-476 of the amino acid sequence represented by UniProtKB:Q13485. UniProtKB:Q13485, 1-476." [PRO:DNx, Reactome:R-HSA-9678447]
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organism-sequence
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PR:000060944 |
mothers against decapentaplegic homolog 4 sequence variant E49* (human)
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hSMAD4/var:E49*
|
"A mothers against decapentaplegic homolog 4 (human) that has has been truncated after the position equivalent to Lys-48 of the amino acid sequence represented by UniProtKB:Q13485. UniProtKB:Q13485, 1-48." [PRO:DNx, Reactome:R-HSA-9675651]
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organism-sequence
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PR:000060985 |
mothers against decapentaplegic homolog 4 sequence variant W398* (human)
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hSMAD4/var:W398*
|
"A mothers against decapentaplegic homolog 4 (human) that has has been truncated after the position equivalent to Val-397 of the amino acid sequence represented by UniProtKB:Q13485. UniProtKB:Q13485, 1-397." [PRO:DNx, Reactome:R-HSA-9678498]
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organism-sequence
|
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PR:000060992 |
mothers against decapentaplegic homolog 4 sequence variant Q183* (human)
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hSMAD4/var:Q183*
|
"A mothers against decapentaplegic homolog 4 (human) that has has been truncated after the position equivalent to Ile-182 of the amino acid sequence represented by UniProtKB:Q13485. UniProtKB:Q13485, 1-182." [PRO:DNx, Reactome:R-HSA-9675176]
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organism-sequence
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PR:000061015 |
mothers against decapentaplegic homolog 4 sequence variant Y95* (human)
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hSMAD4/var:Y95*
|
"A mothers against decapentaplegic homolog 4 (human) that has has been truncated after the position equivalent to Ile-94 of the amino acid sequence represented by UniProtKB:Q13485. UniProtKB:Q13485, 1-94." [PRO:DNx, Reactome:R-HSA-9678478]
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organism-sequence
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PR:000061059 |
mothers against decapentaplegic homolog 4 sequence variant Q116* (human)
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hSMAD4/var:Q116*
|
"A mothers against decapentaplegic homolog 4 (human) that has has been truncated after the position equivalent to Cys-115 of the amino acid sequence represented by UniProtKB:Q13485. UniProtKB:Q13485, 1-115." [PRO:DNx, Reactome:R-HSA-9675166]
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organism-sequence
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PR:000061241 |
mothers against decapentaplegic homolog 4 sequence variant W302* (human)
|
hSMAD4/var:W302*
|
"A mothers against decapentaplegic homolog 4 (human) that has has been truncated after the position equivalent to Tyr-301 of the amino acid sequence represented by UniProtKB:Q13485. UniProtKB:Q13485, 1-301." [PRO:DNx, Reactome:R-HSA-9678490]
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organism-sequence
|
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PR:000061304 |
mothers against decapentaplegic homolog 4 sequence variant E330* (human)
|
hSMAD4/var:E330*
|
"A mothers against decapentaplegic homolog 4 (human) that has has been truncated after the position equivalent to Phe-329 of the amino acid sequence represented by UniProtKB:Q13485. UniProtKB:Q13485, 1-329." [PRO:DNx, Reactome:R-HSA-9675622]
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organism-sequence
|
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PR:000061339 |
mothers against decapentaplegic homolog 4 sequence variant C443* (human)
|
hSMAD4/var:C443*
|
"A mothers against decapentaplegic homolog 4 (human) that has has been truncated after the position equivalent to Gln-442 of the amino acid sequence represented by UniProtKB:Q13485. UniProtKB:Q13485, 1-442." [PRO:DNx, Reactome:R-HSA-9678523]
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organism-sequence
|
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PR:000061457 |
mothers against decapentaplegic homolog 4 sequence variant Q249* (human)
|
hSMAD4/var:Q249*
|
"A mothers against decapentaplegic homolog 4 (human) that has has been truncated after the position equivalent to Gln-248 of the amino acid sequence represented by UniProtKB:Q13485. UniProtKB:Q13485, 1-248." [PRO:DNx, Reactome:R-HSA-9675172]
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organism-sequence
|
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PR:000061581 |
mothers against decapentaplegic homolog 4 sequence variant E108* (human)
|
hSMAD4/var:E108*
|
"A mothers against decapentaplegic homolog 4 (human) that has has been truncated after the position equivalent to Asn-107 of the amino acid sequence represented by UniProtKB:Q13485. UniProtKB:Q13485, 1-107." [PRO:DNx, Reactome:R-HSA-9675640]
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organism-sequence
|
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PR:000061625 |
mothers against decapentaplegic homolog 4 sequence variant Y412* (human)
|
hSMAD4/var:Y412*
|
"A mothers against decapentaplegic homolog 4 (human) that has has been truncated after the position equivalent to Ser-411 of the amino acid sequence represented by UniProtKB:Q13485. UniProtKB:Q13485, 1-411." [PRO:DNx, Reactome:R-HSA-9678469]
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organism-sequence
|
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PR:000061684 |
mothers against decapentaplegic homolog 4 sequence variant W524* (human)
|
hSMAD4/var:W524*
|
"A mothers against decapentaplegic homolog 4 (human) that has has been truncated after the position equivalent to Cys-523 of the amino acid sequence represented by UniProtKB:Q13485. UniProtKB:Q13485, 1-523." [PRO:DNx, Reactome:R-HSA-9678491]
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organism-sequence
|
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PR:000061708 |
mothers against decapentaplegic homolog 4 sequence variant K428R (human)
|
hSMAD4/var:K428R
|
"A mothers against decapentaplegic homolog 4 (human) that has an Arg residue at the position equivalent to Lys-428 of the amino acid sequence represented by UniProtKB:Q13485. UniProtKB:Q13485, Lys-428, CHEBI:29952." [PRO:DNx, Reactome:R-HSA-3311001]
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organism-sequence
|
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PR:000061756 |
mothers against decapentaplegic homolog 4 sequence variant E175* (human)
|
hSMAD4/var:E175*
|
"A mothers against decapentaplegic homolog 4 (human) that has has been truncated after the position equivalent to Thr-174 of the amino acid sequence represented by UniProtKB:Q13485. UniProtKB:Q13485, 1-174." [PRO:DNx, Reactome:R-HSA-9675637]
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organism-sequence
|
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PR:000061768 |
mothers against decapentaplegic homolog 4 sequence variant Q516* (human)
|
hSMAD4/var:Q516*
|
"A mothers against decapentaplegic homolog 4 (human) that has has been truncated after the position equivalent to Arg-515 of the amino acid sequence represented by UniProtKB:Q13485. UniProtKB:Q13485, 1-515." [PRO:DNx, Reactome:R-HSA-9675195]
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organism-sequence
|
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PR:000061774 |
mothers against decapentaplegic homolog 4 sequence variant L440* (human)
|
hSMAD4/var:L440*
|
"A mothers against decapentaplegic homolog 4 (human) that has has been truncated after the position equivalent to Asp-439 of the amino acid sequence represented by UniProtKB:Q13485. UniProtKB:Q13485, 1-439." [PRO:DNx, Reactome:R-HSA-9678510]
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organism-sequence
|
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PR:000061833 |
mothers against decapentaplegic homolog 4 sequence variant Q224* (human)
|
hSMAD4/var:Q224*
|
"A mothers against decapentaplegic homolog 4 (human) that has has been truncated after the position equivalent to Ser-223 of the amino acid sequence represented by UniProtKB:Q13485. UniProtKB:Q13485, 1-223." [PRO:DNx, Reactome:R-HSA-9675168]
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organism-sequence
|
|
PR:000061868 |
mothers against decapentaplegic homolog 4 sequence variant Q256* (human)
|
hSMAD4/var:Q256*
|
"A mothers against decapentaplegic homolog 4 (human) that has has been truncated after the position equivalent to Gly-255 of the amino acid sequence represented by UniProtKB:Q13485. UniProtKB:Q13485, 1-255." [PRO:DNx, Reactome:R-HSA-9675173]
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organism-sequence
|
|
PR:000061967 |
mothers against decapentaplegic homolog 4 sequence variant A406T (human)
|
hSMAD4/var:A406T
|
"A mothers against decapentaplegic homolog 4 (human) that has a Thr residue at the position equivalent to Ala-406 of the amino acid sequence represented by UniProtKB:Q13485. UniProtKB:Q13485, Ala-406, CHEBI:30013." [PRO:DNx, Reactome:R-HSA-3311003]
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organism-sequence
|
|
PR:000061978 |
mothers against decapentaplegic homolog 4 sequence variant W268* (human)
|
hSMAD4/var:W268*
|
"A mothers against decapentaplegic homolog 4 (human) that has has been truncated after the position equivalent to Thr-267 of the amino acid sequence represented by UniProtKB:Q13485. UniProtKB:Q13485, 1-267." [PRO:DNx, Reactome:R-HSA-9678494]
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organism-sequence
|
|
PR:000062067 |
mothers against decapentaplegic homolog 4 sequence variant P356R (human)
|
hSMAD4/var:P356R
|
"A mothers against decapentaplegic homolog 4 (human) that has an Arg residue at the position equivalent to Pro-356 of the amino acid sequence represented by UniProtKB:Q13485. UniProtKB:Q13485, Pro-356, CHEBI:29952." [PRO:DNx, Reactome:R-HSA-3310988]
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organism-sequence
|
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PR:000062090 |
mothers against decapentaplegic homolog 4 sequence variant Q248* (human)
|
hSMAD4/var:Q248*
|
"A mothers against decapentaplegic homolog 4 (human) that has has been truncated after the position equivalent to Gly-247 of the amino acid sequence represented by UniProtKB:Q13485. UniProtKB:Q13485, 1-247." [PRO:DNx, Reactome:R-HSA-9675178]
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organism-sequence
|
|
PR:000062129 |
mothers against decapentaplegic homolog 4 sequence variant Y513* (human)
|
hSMAD4/var:Y513*
|
"A mothers against decapentaplegic homolog 4 (human) that has has been truncated after the position equivalent to Asp-512 of the amino acid sequence represented by UniProtKB:Q13485. UniProtKB:Q13485, 1-512." [PRO:DNx, Reactome:R-HSA-9678471]
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organism-sequence
|
|
PR:000062175 |
mothers against decapentaplegic homolog 4 sequence variant G510* (human)
|
hSMAD4/var:G510*
|
"A mothers against decapentaplegic homolog 4 (human) that has has been truncated after the position equivalent to Trp-509 of the amino acid sequence represented by UniProtKB:Q13485. UniProtKB:Q13485, 1-509." [PRO:DNx, Reactome:R-HSA-9678452]
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organism-sequence
|
|
PR:000062259 |
mothers against decapentaplegic homolog 4 sequence variant G352* (human)
|
hSMAD4/var:G352*
|
"A mothers against decapentaplegic homolog 4 (human) that has has been truncated after the position equivalent to Asp-351 of the amino acid sequence represented by UniProtKB:Q13485. UniProtKB:Q13485, 1-351." [PRO:DNx, Reactome:R-HSA-9678445]
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organism-sequence
|
|
PR:000062302 |
mothers against decapentaplegic homolog 4 sequence variant R361G (human)
|
hSMAD4/var:R361G
|
"A mothers against decapentaplegic homolog 4 (human) that has a Gly residue at the position equivalent to Arg-361 of the amino acid sequence represented by UniProtKB:Q13485. UniProtKB:Q13485, Arg-361, CHEBI:29947." [PRO:DNx, Reactome:R-HSA-3310993]
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organism-sequence
|
|
PR:000062369 |
mothers against decapentaplegic homolog 4 sequence variant E307* (human)
|
hSMAD4/var:E307*
|
"A mothers against decapentaplegic homolog 4 (human) that has has been truncated after the position equivalent to Asn-306 of the amino acid sequence represented by UniProtKB:Q13485. UniProtKB:Q13485, 1-306." [PRO:DNx, Reactome:R-HSA-9675639]
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organism-sequence
|
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PR:000062486 |
mothers against decapentaplegic homolog 4 sequence variant D351Y (human)
|
hSMAD4/var:D351Y
|
"A mothers against decapentaplegic homolog 4 (human) that has a Tyr residue at the position equivalent to Asp-351 of the amino acid sequence represented by UniProtKB:Q13485. UniProtKB:Q13485, Asp-351, CHEBI:46858." [PRO:DNx, Reactome:R-HSA-3310970]
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organism-sequence
|
|
PR:000062687 |
mothers against decapentaplegic homolog 4 sequence variant W509* (human)
|
hSMAD4/var:W509*
|
"A mothers against decapentaplegic homolog 4 (human) that has has been truncated after the position equivalent to Gly-508 of the amino acid sequence represented by UniProtKB:Q13485. UniProtKB:Q13485, 1-508." [PRO:DNx, Reactome:R-HSA-9678497]
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organism-sequence
|
|
PR:000062700 |
mothers against decapentaplegic homolog 4 sequence variant K428T (human)
|
hSMAD4/var:K428T
|
"A mothers against decapentaplegic homolog 4 (human) that has a Thr residue at the position equivalent to Lys-428 of the amino acid sequence represented by UniProtKB:Q13485. UniProtKB:Q13485, Lys-428, CHEBI:30013." [PRO:DNx, Reactome:R-HSA-3311004]
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organism-sequence
|
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PR:000062729 |
mothers against decapentaplegic homolog 4 sequence variant Q366* (human)
|
hSMAD4/var:Q366*
|
"A mothers against decapentaplegic homolog 4 (human) that has has been truncated after the position equivalent to Gly-365 of the amino acid sequence represented by UniProtKB:Q13485. UniProtKB:Q13485, 1-365." [PRO:DNx, Reactome:R-HSA-9675200]
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organism-sequence
|
|
PR:000062770 |
mothers against decapentaplegic homolog 4 sequence variant R361S (human)
|
hSMAD4/var:R361S
|
"A mothers against decapentaplegic homolog 4 (human) that has a Ser residue at the position equivalent to Arg-361 of the amino acid sequence represented by UniProtKB:Q13485. UniProtKB:Q13485, Arg-361, CHEBI:29999." [PRO:DNx, Reactome:R-HSA-3310994]
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organism-sequence
|
|
PR:000062793 |
mothers against decapentaplegic homolog 4 sequence variant Y195* (human)
|
hSMAD4/var:Y195*
|
"A mothers against decapentaplegic homolog 4 (human) that has has been truncated after the position equivalent to Thr-194 of the amino acid sequence represented by UniProtKB:Q13485. UniProtKB:Q13485, 1-194." [PRO:DNx, Reactome:R-HSA-9678462]
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organism-sequence
|
|
PR:000062878 |
mothers against decapentaplegic homolog 4 sequence variant Y328* (human)
|
hSMAD4/var:Y328*
|
"A mothers against decapentaplegic homolog 4 (human) that has has been truncated after the position equivalent to Ala-327 of the amino acid sequence represented by UniProtKB:Q13485. UniProtKB:Q13485, 1-327." [PRO:DNx, Reactome:R-HSA-9678470]
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organism-sequence
|
|
PR:000062888 |
mothers against decapentaplegic homolog 4 sequence variant Q289* (human)
|
hSMAD4/var:Q289*
|
"A mothers against decapentaplegic homolog 4 (human) that has has been truncated after the position equivalent to Leu-288 of the amino acid sequence represented by UniProtKB:Q13485. UniProtKB:Q13485, 1-288." [PRO:DNx, Reactome:R-HSA-9675177]
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organism-sequence
|
|
PR:000062894 |
mothers against decapentaplegic homolog 4 sequence variant S154* (human)
|
hSMAD4/var:S154*
|
"A mothers against decapentaplegic homolog 4 (human) that has has been truncated after the position equivalent to Pro-153 of the amino acid sequence represented by UniProtKB:Q13485. UniProtKB:Q13485, 1-153." [PRO:DNx, Reactome:R-HSA-9675621]
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organism-sequence
|
|
PR:000062923 |
mothers against decapentaplegic homolog 4 sequence variant W101* (human)
|
hSMAD4/var:W101*
|
"A mothers against decapentaplegic homolog 4 (human) that has has been truncated after the position equivalent to Arg-100 of the amino acid sequence represented by UniProtKB:Q13485. UniProtKB:Q13485, 1-100." [PRO:DNx, Reactome:R-HSA-9678492]
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organism-sequence
|
|
PR:000062931 |
mothers against decapentaplegic homolog 4 sequence variant Q534* (human)
|
hSMAD4/var:Q534*
|
"A mothers against decapentaplegic homolog 4 (human) that has has been truncated after the position equivalent to Leu-533 of the amino acid sequence represented by UniProtKB:Q13485. UniProtKB:Q13485, 1-533." [PRO:DNx, Reactome:R-HSA-9675197]
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organism-sequence
|
|
PR:000062943 |
mothers against decapentaplegic homolog 4 sequence variant L146* (human)
|
hSMAD4/var:L146*
|
"A mothers against decapentaplegic homolog 4 (human) that has has been truncated after the position equivalent to Gly-145 of the amino acid sequence represented by UniProtKB:Q13485. UniProtKB:Q13485, 1-145." [PRO:DNx, Reactome:R-HSA-9678509]
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organism-sequence
|
|
PR:000062969 |
mothers against decapentaplegic homolog 4 sequence variant Q455* (human)
|
hSMAD4/var:Q455*
|
"A mothers against decapentaplegic homolog 4 (human) that has has been truncated after the position equivalent to Ala-454 of the amino acid sequence represented by UniProtKB:Q13485. UniProtKB:Q13485, 1-454." [PRO:DNx, Reactome:R-HSA-9675193]
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organism-sequence
|
|
PR:000063050 |
mothers against decapentaplegic homolog 4 sequence variant K122* (human)
|
hSMAD4/var:K122*
|
"A mothers against decapentaplegic homolog 4 (human) that has has been truncated after the position equivalent to Leu-121 of the amino acid sequence represented by UniProtKB:Q13485. UniProtKB:Q13485, 1-121." [PRO:DNx, Reactome:R-HSA-9678515]
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organism-sequence
|
|
PR:000063052 |
mothers against decapentaplegic homolog 4 sequence variant R515T (human)
|
hSMAD4/var:R515T
|
"A mothers against decapentaplegic homolog 4 (human) that has a Thr residue at the position equivalent to Arg-515 of the amino acid sequence represented by UniProtKB:Q13485. UniProtKB:Q13485, Arg-515, CHEBI:30013." [PRO:DNx, Reactome:R-HSA-3311008]
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organism-sequence
|
|
PR:000063094 |
mothers against decapentaplegic homolog 4 sequence variant P356L (human)
|
hSMAD4/var:P356L
|
"A mothers against decapentaplegic homolog 4 (human) that has a Leu residue at the position equivalent to Pro-356 of the amino acid sequence represented by UniProtKB:Q13485. UniProtKB:Q13485, Pro-356, CHEBI:30006." [PRO:DNx, Reactome:R-HSA-3310987]
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organism-sequence
|
|
PR:000063098 |
mothers against decapentaplegic homolog 4 sequence variant E417* (human)
|
hSMAD4/var:E417*
|
"A mothers against decapentaplegic homolog 4 (human) that has has been truncated after the position equivalent to Arg-416 of the amino acid sequence represented by UniProtKB:Q13485. UniProtKB:Q13485, 1-416." [PRO:DNx, Reactome:R-HSA-9675623]
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organism-sequence
|
|
PR:000063207 |
mothers against decapentaplegic homolog 4 sequence variant Q311* (human)
|
hSMAD4/var:Q311*
|
"A mothers against decapentaplegic homolog 4 (human) that has has been truncated after the position equivalent to Phe-310 of the amino acid sequence represented by UniProtKB:Q13485. UniProtKB:Q13485, 1-310." [PRO:DNx, Reactome:R-HSA-9675169]
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organism-sequence
|
|
PR:000063208 |
mothers against decapentaplegic homolog 4 sequence variant Y260* (human)
|
hSMAD4/var:Y260*
|
"A mothers against decapentaplegic homolog 4 (human) that has has been truncated after the position equivalent to Thr-259 of the amino acid sequence represented by UniProtKB:Q13485. UniProtKB:Q13485, 1-259." [PRO:DNx, Reactome:R-HSA-9678477]
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organism-sequence
|
|
PR:000063251 |
mothers against decapentaplegic homolog 4 sequence variant Q239* (human)
|
hSMAD4/var:Q239*
|
"A mothers against decapentaplegic homolog 4 (human) that has has been truncated after the position equivalent to Leu-238 of the amino acid sequence represented by UniProtKB:Q13485. UniProtKB:Q13485, 1-238." [PRO:DNx, Reactome:R-HSA-9675174]
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organism-sequence
|
|
PR:000063265 |
mothers against decapentaplegic homolog 4 sequence variant S242* (human)
|
hSMAD4/var:S242*
|
"A mothers against decapentaplegic homolog 4 (human) that has has been truncated after the position equivalent to Ala-241 of the amino acid sequence represented by UniProtKB:Q13485. UniProtKB:Q13485, 1-241." [PRO:DNx, Reactome:R-HSA-9675167]
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| | | |
organism-sequence
|
|
PR:000063355 |
mothers against decapentaplegic homolog 4 sequence variant S138* (human)
|
hSMAD4/var:S138*
|
"A mothers against decapentaplegic homolog 4 (human) that has has been truncated after the position equivalent to Val-137 of the amino acid sequence represented by UniProtKB:Q13485. UniProtKB:Q13485, 1-137." [PRO:DNx, Reactome:R-HSA-9675649]
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organism-sequence
|
|
PR:000063397 |
mothers against decapentaplegic homolog 4 sequence variant Q442* (human)
|
hSMAD4/var:Q442*
|
"A mothers against decapentaplegic homolog 4 (human) that has has been truncated after the position equivalent to Arg-441 of the amino acid sequence represented by UniProtKB:Q13485. UniProtKB:Q13485, 1-441." [PRO:DNx, Reactome:R-HSA-9675194]
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organism-sequence
|
|
PR:000063419 |
mothers against decapentaplegic homolog 4 sequence variant R515* (human)
|
hSMAD4/var:R515*
|
"A mothers against decapentaplegic homolog 4 (human) that has has been truncated after the position equivalent to Pro-514 of the amino acid sequence represented by UniProtKB:Q13485. UniProtKB:Q13485, 1-514." [PRO:DNx, Reactome:R-HSA-3311012]
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organism-sequence
|
|
PR:000063609 |
mothers against decapentaplegic homolog 4 sequence variant G168* (human)
|
hSMAD4/var:G168*
|
"A mothers against decapentaplegic homolog 4 (human) that has has been truncated after the position equivalent to Glu-167 of the amino acid sequence represented by UniProtKB:Q13485. UniProtKB:Q13485, 1-167." [PRO:DNx, Reactome:R-HSA-9678451]
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organism-sequence
|
|
PR:000063714 |
mothers against decapentaplegic homolog 4 sequence variant E520* (human)
|
hSMAD4/var:E520*
|
"A mothers against decapentaplegic homolog 4 (human) that has has been truncated after the position equivalent to Lys-519 of the amino acid sequence represented by UniProtKB:Q13485. UniProtKB:Q13485, 1-519." [PRO:DNx, Reactome:R-HSA-9675636]
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organism-sequence
|
|
PR:000063741 |
mothers against decapentaplegic homolog 4 sequence variant E205* (human)
|
hSMAD4/var:E205*
|
"A mothers against decapentaplegic homolog 4 (human) that has has been truncated after the position equivalent to Ser-204 of the amino acid sequence represented by UniProtKB:Q13485. UniProtKB:Q13485, 1-204." [PRO:DNx, Reactome:R-HSA-9675650]
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| | | |
organism-sequence
|
|
PR:000063751 |
mothers against decapentaplegic homolog 4 sequence variant E53* (human)
|
hSMAD4/var:E53*
|
"A mothers against decapentaplegic homolog 4 (human) that has has been truncated after the position equivalent to Asp-52 of the amino acid sequence represented by UniProtKB:Q13485. UniProtKB:Q13485, 1-52." [PRO:DNx, Reactome:R-HSA-9675633]
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organism-sequence
|
|
PR:000063757 |
mothers against decapentaplegic homolog 4 sequence variant R135* (human)
|
hSMAD4/var:R135*
|
"A mothers against decapentaplegic homolog 4 (human) that has has been truncated after the position equivalent to Glu-134 of the amino acid sequence represented by UniProtKB:Q13485. UniProtKB:Q13485, 1-134." [PRO:DNx, Reactome:R-HSA-9675090]
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organism-sequence
|
|
PR:000063792 |
mothers against decapentaplegic homolog 4 sequence variant Q334* (human)
|
hSMAD4/var:Q334*
|
"A mothers against decapentaplegic homolog 4 (human) that has has been truncated after the position equivalent to Val-333 of the amino acid sequence represented by UniProtKB:Q13485. UniProtKB:Q13485, 1-333." [PRO:DNx, Reactome:R-HSA-9675191]
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organism-sequence
|
|
PR:000063853 |
mothers against decapentaplegic homolog 4 sequence variant Y322* (human)
|
hSMAD4/var:Y322*
|
"A mothers against decapentaplegic homolog 4 (human) that has has been truncated after the position equivalent to Glu-321 of the amino acid sequence represented by UniProtKB:Q13485. UniProtKB:Q13485, 1-321." [PRO:DNx, Reactome:R-HSA-9678479]
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organism-sequence
|
|
PR:000063915 |
mothers against decapentaplegic homolog 4 sequence variant Q245* (human)
|
hSMAD4/var:Q245*
|
"A mothers against decapentaplegic homolog 4 (human) that has has been truncated after the position equivalent to Pro-244 of the amino acid sequence represented by UniProtKB:Q13485. UniProtKB:Q13485, 1-244." [PRO:DNx, Reactome:R-HSA-9675175]
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organism-sequence
|
|
PR:000063918 |
mothers against decapentaplegic homolog 4 sequence variant S144* (human)
|
hSMAD4/var:S144*
|
"A mothers against decapentaplegic homolog 4 (human) that has has been truncated after the position equivalent to Leu-143 of the amino acid sequence represented by UniProtKB:Q13485. UniProtKB:Q13485, 1-143." [PRO:DNx, Reactome:R-HSA-9675625]
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organism-sequence
|
|
PR:000064002 |
mothers against decapentaplegic homolog 4 sequence variant Q250* (human)
|
hSMAD4/var:Q250*
|
"A mothers against decapentaplegic homolog 4 (human) that has has been truncated after the position equivalent to Gln-249 of the amino acid sequence represented by UniProtKB:Q13485. UniProtKB:Q13485, 1-249." [PRO:DNx, Reactome:R-HSA-9675170]
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organism-sequence
|
|
PR:000064188 |
mothers against decapentaplegic homolog 4 sequence variant S178* (human)
|
hSMAD4/var:S178*
|
"A mothers against decapentaplegic homolog 4 (human) that has has been truncated after the position equivalent to His-177 of the amino acid sequence represented by UniProtKB:Q13485. UniProtKB:Q13485, 1-177." [PRO:DNx, Reactome:R-HSA-9675630]
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organism-sequence
|
|
PR:000064193 |
mothers against decapentaplegic homolog 4 sequence variant E33* (human)
|
hSMAD4/var:E33*
|
"A mothers against decapentaplegic homolog 4 (human) that has has been truncated after the position equivalent to Ser-32 of the amino acid sequence represented by UniProtKB:Q13485. UniProtKB:Q13485, 1-32." [PRO:DNx, Reactome:R-HSA-9675654]
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organism-sequence
|
|
PR:000064298 |
mothers against decapentaplegic homolog 4 sequence variant S171* (human)
|
hSMAD4/var:S171*
|
"A mothers against decapentaplegic homolog 4 (human) that has has been truncated after the position equivalent to Pro-170 of the amino acid sequence represented by UniProtKB:Q13485. UniProtKB:Q13485, 1-170." [PRO:DNx, Reactome:R-HSA-9675634]
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organism-sequence
|
|
PR:000064338 |
mothers against decapentaplegic homolog 4 sequence variant Y430* (human)
|
hSMAD4/var:Y430*
|
"A mothers against decapentaplegic homolog 4 (human) that has has been truncated after the position equivalent to Ile-429 of the amino acid sequence represented by UniProtKB:Q13485. UniProtKB:Q13485, 1-429." [PRO:DNx, Reactome:R-HSA-9678476]
|
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organism-sequence
|
|
PR:000064356 |
mothers against decapentaplegic homolog 4 sequence variant S343* (human)
|
hSMAD4/var:S343*
|
"A mothers against decapentaplegic homolog 4 (human) that has has been truncated after the position equivalent to Pro-342 of the amino acid sequence represented by UniProtKB:Q13485. UniProtKB:Q13485, 1-342." [PRO:DNx, Reactome:R-HSA-9675641]
|
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| | | |
organism-sequence
|
|
PR:000064413 |
mothers against decapentaplegic homolog 4 sequence variant Q448* (human)
|
hSMAD4/var:Q448*
|
"A mothers against decapentaplegic homolog 4 (human) that has has been truncated after the position equivalent to Met-447 of the amino acid sequence represented by UniProtKB:Q13485. UniProtKB:Q13485, 1-447." [PRO:DNx, Reactome:R-HSA-9675192]
|
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| | | |
organism-sequence
|
|
PR:000064414 |
mothers against decapentaplegic homolog 4 sequence variant L172* (human)
|
hSMAD4/var:L172*
|
"A mothers against decapentaplegic homolog 4 (human) that has has been truncated after the position equivalent to Ser-171 of the amino acid sequence represented by UniProtKB:Q13485. UniProtKB:Q13485, 1-171." [PRO:DNx, Reactome:R-HSA-9678514]
|
|
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| | | |
organism-sequence
|
|
PR:000064437 |
mothers against decapentaplegic homolog 4 sequence variant E321* (human)
|
hSMAD4/var:E321*
|
"A mothers against decapentaplegic homolog 4 (human) that has has been truncated after the position equivalent to Pro-320 of the amino acid sequence represented by UniProtKB:Q13485. UniProtKB:Q13485, 1-320." [PRO:DNx, Reactome:R-HSA-9675658]
|
|
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| | | |
organism-sequence
|
|
PR:000064488 |
mothers against decapentaplegic homolog 4 sequence variant R361H (human)
|
hSMAD4/var:R361H
|
"A mothers against decapentaplegic homolog 4 (human) that has a His residue at the position equivalent to Arg-361 of the amino acid sequence represented by UniProtKB:Q13485. UniProtKB:Q13485, Arg-361, CHEBI:29979." [PRO:DNx, Reactome:R-HSA-3310984]
|
|
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| | | |
organism-sequence
|
|
PR:Q13485-1 |
mothers against decapentaplegic homolog 4 isoform 1 (human)
|
hSMAD4/iso:1
|
"A smad4 isoform 1 that is encoded in the genome of human." [PRO:CNA]
|
Yes |
Yes |
|
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|
| | | | | | | | |
| |
organism-modification
|
|
PR:000025956 |
mothers against decapentaplegic homolog 4 isoform 1 monoubiquitinated 1 (human)
|
hSMAD4/iso:1/MonoUbiq:1
|
"A smad4 isoform 1 monoubiquitinated 1 in human. UniProtKB:Q13485-1, Lys-507, MOD:01148." [PMID:18783722]
|
|
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| |
organism-modification
|
|
PR:000025958 |
mothers against decapentaplegic homolog 4 isoform 1 monoubiquitinated 2 (human)
|
hSMAD4/iso:1/MonoUbiq:2
|
"A smad4 isoform 1 monoubiquitinated 2 in human. UniProtKB:Q13485-1, Lys-519, MOD:01148." [PMID:19135894]
|
Yes |
|
|
|
|
|
| | | | | | | | |
| |
organism-modification
|
|
PR:000036483 |
mothers against decapentaplegic homolog 4 isoform 1 phosphorylated 1 (human)
|
hSMAD4/iso:1/Phos:1
|
"A smad4 isoform 1 phosphorylated 1 in human. UniProtKB:Q13485-1, Thr-277, MOD:00047." [PMID:12801888, PRO:CNA]
|
Yes |
|
|
|
|
|
| | | | | | |
| | | |
organism-modification
|
|
PR:000045915 |
mothers against decapentaplegic homolog 4 phosphorylated 1 (human)
|
hSMAD4/Phos:1
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"A mothers against decapentaplegic homolog 4 (human) that has been phosphorylated at Thr-77. UniProtKB:Q13485, Thr-77, MOD:00047." [iPTMnet:Q13485, PMID:20974850]
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organism-modification
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PR:000049288 |
mothers against decapentaplegic homolog 4 ADP-ribosylated form (human)
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hSMAD4/ADPribRes+
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"A mothers against decapentaplegic homolog 4 (human) that includes at least one ADP-ribosylated residue. UniProtKB:Q13485, MOD:00752." [PRO:DNx, Reactome:R-HSA-2187323]
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organism-modification
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PR:000064798 |
mothers against decapentaplegic homolog 4 ubiquitinated form (human)
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hSMAD4/UbiqLys+
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"A mothers against decapentaplegic homolog 4 (human) that includes at least one ubiquitinated lysine. UniProtKB:Q13485, MOD:01148." [PRO:DNx, Reactome:R-HSA-9773859, Reactome:R-HSA-9773863]
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organism-modification
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PR:000067581 |
mothers against decapentaplegic homolog 4 methylated 1 (human)
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hSMAD4/Me:1
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"A mothers against decapentaplegic homolog 4 (human) that has been methylated on the residue at the position equivalent to Cys-127 of the amino acid sequence represented by UniProtKB:Q13485. UniProtKB:Q13485, Cys-127, MOD:00660." [IEDB_epitope:1004378, PRO:DNx]
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organism-modification
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PR:000074844 |
mothers against decapentaplegic homolog 4 methylated 2 (human)
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hSMAD4/Me:2
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"A mothers against decapentaplegic homolog 4 (human) that has been methylated on the residue at the position equivalent to Cys-123 of the amino acid sequence represented by UniProtKB:Q13485. UniProtKB:Q13485, Cys-123, MOD:00660." [IEDB_epitope:1060570, PRO:DNx]
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organism-modification
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PR:000075597 |
mothers against decapentaplegic homolog 4 deaminated 1 (human)
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hSMAD4/Deam:1
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"A mothers against decapentaplegic homolog 4 (human) that has been deaminated on the residue at the position equivalent to Gln-410 of the amino acid sequence represented by UniProtKB:Q13485. UniProtKB:Q13485, Gln-410, MOD:00685." [IEDB_epitope:1563936, PRO:DNx]
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organism-modification
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PR:000083975 |
mothers against decapentaplegic homolog 4 methylated 3 (human)
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hSMAD4/Me:3
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"A mothers against decapentaplegic homolog 4 (human) that has been methylated on the residue at the position equivalent to Cys-401 of the amino acid sequence represented by UniProtKB:Q13485. UniProtKB:Q13485, Cys-401, MOD:00660." [IEDB_epitope:1014599, PRO:DNx]
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sequence
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PR:000000366 |
smad4 isoform 1
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SMAD4/iso:1
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"A smad4 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13485-1 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]
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Yes |
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organism-sequence
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PR:P97471-1 |
mothers against decapentaplegic homolog 4 isoform 1 (mouse)
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mSMAD4/iso:1
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"A smad4 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]
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Yes |
Yes |
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organism-sequence
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PR:Q13485-1 |
mothers against decapentaplegic homolog 4 isoform 1 (human)
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hSMAD4/iso:1
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"A smad4 isoform 1 that is encoded in the genome of human." [PRO:CNA]
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Yes |
Yes |
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organism-modification
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PR:000025956 |
mothers against decapentaplegic homolog 4 isoform 1 monoubiquitinated 1 (human)
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hSMAD4/iso:1/MonoUbiq:1
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"A smad4 isoform 1 monoubiquitinated 1 in human. UniProtKB:Q13485-1, Lys-507, MOD:01148." [PMID:18783722]
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organism-modification
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PR:000025958 |
mothers against decapentaplegic homolog 4 isoform 1 monoubiquitinated 2 (human)
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hSMAD4/iso:1/MonoUbiq:2
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"A smad4 isoform 1 monoubiquitinated 2 in human. UniProtKB:Q13485-1, Lys-519, MOD:01148." [PMID:19135894]
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Yes |
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organism-modification
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PR:000036483 |
mothers against decapentaplegic homolog 4 isoform 1 phosphorylated 1 (human)
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hSMAD4/iso:1/Phos:1
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"A smad4 isoform 1 phosphorylated 1 in human. UniProtKB:Q13485-1, Thr-277, MOD:00047." [PMID:12801888, PRO:CNA]
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Yes |
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modification
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PR:000000476 |
smad4 isoform 1 phosphorylated form
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SMAD4/iso:1/PhosRes+
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"A smad4 isoform 1 that includes at least one phosphorylated residue." [PRO:CNA]
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modification
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PR:000000579 |
smad4 isoform 1 phosphorylated 1
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SMAD4/iso:1/Phos:1
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"A smad4 isoform 1 phosphorylated form in which the phosphorylation occurs within the PxTP motif located in the MH1-MH2 domain linker region. Example: UniProtKB:Q13485-1, Thr-277, MOD:00047." [PMID:12801888]
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organism-modification
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PR:000036483 |
mothers against decapentaplegic homolog 4 isoform 1 phosphorylated 1 (human)
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hSMAD4/iso:1/Phos:1
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"A smad4 isoform 1 phosphorylated 1 in human. UniProtKB:Q13485-1, Thr-277, MOD:00047." [PMID:12801888, PRO:CNA]
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Yes |
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modification
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PR:000002539 |
smad4 isoform 1 unmodified form
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SMAD4/iso:1/UnMod
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"A smad4 isoform 1 that has not been subjected to any co- or post-translational residue modification or peptide bond cleavage." [PRO:DNx]
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modification
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PR:000025955 |
smad4 isoform 1 monoubiquitinated 1
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SMAD4/iso:1/MonoUbiq:1
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"A smad4 isoform 1 that has been monoubiquitinated on a lysine residue within the MH2 domain. Example: UniProtKB:Q13485-1, Lys-507, MOD:01148." [PMID:18783722]
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organism-modification
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PR:000025956 |
mothers against decapentaplegic homolog 4 isoform 1 monoubiquitinated 1 (human)
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hSMAD4/iso:1/MonoUbiq:1
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"A smad4 isoform 1 monoubiquitinated 1 in human. UniProtKB:Q13485-1, Lys-507, MOD:01148." [PMID:18783722]
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modification
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PR:000025957 |
smad4 isoform 1 monoubiquitinated 2
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SMAD4/iso:1/MonoUbiq:2
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"A smad4 isoform 1 that has been monoubiquitinated on a lysine residue within the MH2 domain by E3 ubiquitin-protein ligase TRIM33. Example: UniProtKB:Q13485-1, Lys-519, MOD:01148." [PMID:18783722]
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organism-modification
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PR:000025958 |
mothers against decapentaplegic homolog 4 isoform 1 monoubiquitinated 2 (human)
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hSMAD4/iso:1/MonoUbiq:2
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"A smad4 isoform 1 monoubiquitinated 2 in human. UniProtKB:Q13485-1, Lys-519, MOD:01148." [PMID:19135894]
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Yes |
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