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sequence
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 PR:000000366 |
   smad4 isoform 1
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   SMAD4/iso:1
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  "A smad4 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13485-1 or a 1:1 ortholog thereof." [PRO:CNA, PRO:DAN]
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|  Yes |
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organism-sequence
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 PR:P97471-1 |
   mothers against decapentaplegic homolog 4 isoform 1 (mouse)
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   mSMAD4/iso:1
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  "A smad4 isoform 1 that is encoded in the genome of mouse." [PRO:CNA]
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 Yes |  Yes |
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organism-sequence
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 PR:Q13485-1 |
   mothers against decapentaplegic homolog 4 isoform 1 (human)
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   hSMAD4/iso:1
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  "A smad4 isoform 1 that is encoded in the genome of human." [PRO:CNA]
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 Yes |  Yes |
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organism-modification
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 PR:000025956 |
   mothers against decapentaplegic homolog 4 isoform 1 monoubiquitinated 1 (human)
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   hSMAD4/iso:1/MonoUbiq:1
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  "A smad4 isoform 1 monoubiquitinated 1 in human. UniProtKB:Q13485-1, Lys-507, MOD:01148." [PMID:18783722]
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organism-modification
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|
 PR:000025958 |
   mothers against decapentaplegic homolog 4 isoform 1 monoubiquitinated 2 (human)
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   hSMAD4/iso:1/MonoUbiq:2
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  "A smad4 isoform 1 monoubiquitinated 2 in human. UniProtKB:Q13485-1, Lys-519, MOD:01148." [PMID:19135894]
 |
 Yes | 
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organism-modification
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 PR:000036483 |
   mothers against decapentaplegic homolog 4 isoform 1 phosphorylated 1 (human)
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   hSMAD4/iso:1/Phos:1
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  "A smad4 isoform 1 phosphorylated 1 in human. UniProtKB:Q13485-1, Thr-277, MOD:00047." [PMID:12801888, PRO:CNA]
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 Yes | 
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modification
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|
 PR:000000476 |
   smad4 isoform 1 phosphorylated form
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   SMAD4/iso:1/PhosRes+
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  "A smad4 isoform 1 that includes at least one phosphorylated residue." [PRO:CNA]
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modification
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|
 PR:000000579 |
   smad4 isoform 1 phosphorylated 1
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   SMAD4/iso:1/Phos:1
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  "A smad4 isoform 1 phosphorylated form in which the phosphorylation occurs within the PxTP motif located in the MH1-MH2 domain linker region. Example: UniProtKB:Q13485-1, Thr-277, MOD:00047." [PMID:12801888]
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|  |  |  |  |  |  |  |  |
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organism-modification
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|
 PR:000036483 |
   mothers against decapentaplegic homolog 4 isoform 1 phosphorylated 1 (human)
 |
   hSMAD4/iso:1/Phos:1
 |
  "A smad4 isoform 1 phosphorylated 1 in human. UniProtKB:Q13485-1, Thr-277, MOD:00047." [PMID:12801888, PRO:CNA]
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 Yes | 
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|  |  |  |  |
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modification
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|
 PR:000002539 |
   smad4 isoform 1 unmodified form
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   SMAD4/iso:1/UnMod
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  "A smad4 isoform 1 that has not been subjected to any co- or post-translational residue modification or peptide bond cleavage." [PRO:DNx]
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modification
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|
 PR:000025955 |
   smad4 isoform 1 monoubiquitinated 1
 |
   SMAD4/iso:1/MonoUbiq:1
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  "A smad4 isoform 1 that has been monoubiquitinated on a lysine residue within the MH2 domain. Example: UniProtKB:Q13485-1, Lys-507, MOD:01148." [PMID:18783722]
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|  |  |  |  |  |  |
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organism-modification
 |


|
 PR:000025956 |
   mothers against decapentaplegic homolog 4 isoform 1 monoubiquitinated 1 (human)
 |
   hSMAD4/iso:1/MonoUbiq:1
 |
  "A smad4 isoform 1 monoubiquitinated 1 in human. UniProtKB:Q13485-1, Lys-507, MOD:01148." [PMID:18783722]
 |

| 
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|  |  |  |  |
 |  |  |  |  |
modification
 |


|
 PR:000025957 |
   smad4 isoform 1 monoubiquitinated 2
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   SMAD4/iso:1/MonoUbiq:2
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  "A smad4 isoform 1 that has been monoubiquitinated on a lysine residue within the MH2 domain by E3 ubiquitin-protein ligase TRIM33. Example: UniProtKB:Q13485-1, Lys-519, MOD:01148." [PMID:18783722]
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|  |  |  |  |  |  |
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organism-modification
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|
 PR:000025958 |
   mothers against decapentaplegic homolog 4 isoform 1 monoubiquitinated 2 (human)
 |
   hSMAD4/iso:1/MonoUbiq:2
 |
  "A smad4 isoform 1 monoubiquitinated 2 in human. UniProtKB:Q13485-1, Lys-519, MOD:01148." [PMID:19135894]
 |
 Yes | 
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