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 |
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family
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|
PR:000002197 |
caspase-8-like protease
|
APAF1
|
"A protein that is a translation product of the human CASP8, CASP10, or CFLAR genes, 1:1 orthologs thereof, or a semi-ortholog thereof. The core domain architecture consists of two consecutive copies of the Death effector domain (DED) domain (Pfam:PF01335) in an amino-terminal propeptide followed by Peptidase_C14 domain (Pfam:PF00656). Encoded as zymogens, the activated proteins are cysteine proteases typically involved in apoptosis." [PRO:DAN, PRO:WCB]
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gene
|
|
PR:000002282 |
CASP8 and FADD-like apoptosis regulator
|
CFLAR
|
"A caspase-8-like protease that is a translation product of the human CFLAR gene or a 1:1 ortholog thereof." [PRO:WCB]
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organism-gene
|
|
PR:O15519 |
CASP8 and FADD-like apoptosis regulator (human)
|
hCFLAR
|
"A CASP8 and FADD-like apoptosis regulator that is encoded in the genome of human." [PRO:WCB, UniProtKB:O15519]
|
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| |
organism-sequence
|
|
PR:O15519-1 |
CASP8 and FADD-like apoptosis regulator isoform h1 (human)
|
hCFLAR/iso:h1
|
"A CASP8 and FADD-like apoptosis regulator (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O15519-1." [PRO:DNx, UniProtKB:O15519]
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organism-modification
|
|
PR:000064786 |
CASP8 and FADD-like apoptosis regulator isoform h1 ubiquitinated 1 (human)
|
hCFLAR/iso:h1/Ubiq:1
|
"A CASP8 and FADD-like apoptosis regulator isoform h1 (human) that has been ubiquitinated on the residues at the positions equivalent to Lys-460, Lys-462, Lys-473, and Lys-474 of the amino acid sequence represented by UniProtKB:O15519-1. UniProtKB:O15519-1, Lys-460/Lys-462/Lys-473/Lys-474, MOD:01148." [PRO:DNx, Reactome:R-HSA-9818805]
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| |
organism-sequence
|
|
PR:O15519-10 |
CASP8 and FADD-like apoptosis regulator isoform h10 (human)
|
hCFLAR/iso:h10
|
"A CASP8 and FADD-like apoptosis regulator (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O15519-10." [PRO:DNx, UniProtKB:O15519]
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| |
organism-sequence
|
|
PR:O15519-11 |
CASP8 and FADD-like apoptosis regulator isoform h11 (human)
|
hCFLAR/iso:h11
|
"A CASP8 and FADD-like apoptosis regulator (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O15519-11." [PRO:DNx, UniProtKB:O15519]
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| |
organism-sequence
|
|
PR:O15519-12 |
CASP8 and FADD-like apoptosis regulator isoform h12 (human)
|
hCFLAR/iso:h12
|
"A CASP8 and FADD-like apoptosis regulator (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O15519-12." [PRO:DNx, UniProtKB:O15519]
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| |
organism-sequence
|
|
PR:O15519-13 |
CASP8 and FADD-like apoptosis regulator isoform h13 (human)
|
hCFLAR/iso:h13
|
"A CASP8 and FADD-like apoptosis regulator (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O15519-13." [PRO:DNx, UniProtKB:O15519]
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| | | | | | | | |
| |
organism-sequence
|
|
PR:O15519-14 |
CASP8 and FADD-like apoptosis regulator isoform h14 (human)
|
hCFLAR/iso:h14
|
"A CASP8 and FADD-like apoptosis regulator (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O15519-14." [PRO:DNx, UniProtKB:O15519]
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| |
organism-sequence
|
|
PR:O15519-15 |
CASP8 and FADD-like apoptosis regulator isoform h15 (human)
|
hCFLAR/iso:h15
|
"A CASP8 and FADD-like apoptosis regulator (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O15519-15." [PRO:DNx, UniProtKB:O15519]
|
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| |
organism-sequence
|
|
PR:O15519-2 |
CASP8 and FADD-like apoptosis regulator isoform h2 (human)
|
hCFLAR/iso:h2
|
"A CASP8 and FADD-like apoptosis regulator (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O15519-2." [PRO:DNx, UniProtKB:O15519]
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| | | | | | | | |
| |
organism-sequence
|
|
PR:O15519-3 |
CASP8 and FADD-like apoptosis regulator isoform h3 (human)
|
hCFLAR/iso:h3
|
"A CASP8 and FADD-like apoptosis regulator (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O15519-3." [PRO:DNx, UniProtKB:O15519]
|
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| | | | | | | | |
| |
organism-sequence
|
|
PR:O15519-4 |
CASP8 and FADD-like apoptosis regulator isoform h4 (human)
|
hCFLAR/iso:h4
|
"A CASP8 and FADD-like apoptosis regulator (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O15519-4." [PRO:DNx, UniProtKB:O15519]
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| | | | | | | | |
| |
organism-sequence
|
|
PR:O15519-5 |
CASP8 and FADD-like apoptosis regulator isoform h5 (human)
|
hCFLAR/iso:h5
|
"A CASP8 and FADD-like apoptosis regulator (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O15519-5." [PRO:DNx, UniProtKB:O15519]
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|
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| | | | | | | | |
| |
organism-sequence
|
|
PR:O15519-6 |
CASP8 and FADD-like apoptosis regulator isoform h6 (human)
|
hCFLAR/iso:h6
|
"A CASP8 and FADD-like apoptosis regulator (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O15519-6." [PRO:DNx, UniProtKB:O15519]
|
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| | | | | | | | |
| |
organism-sequence
|
|
PR:O15519-7 |
CASP8 and FADD-like apoptosis regulator isoform h7 (human)
|
hCFLAR/iso:h7
|
"A CASP8 and FADD-like apoptosis regulator (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O15519-7." [PRO:DNx, UniProtKB:O15519]
|
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| | | | | | | | |
| |
organism-sequence
|
|
PR:O15519-8 |
CASP8 and FADD-like apoptosis regulator isoform h8 (human)
|
hCFLAR/iso:h8
|
"A CASP8 and FADD-like apoptosis regulator (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O15519-8." [PRO:DNx, UniProtKB:O15519]
|
|
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| | | | | | | | |
| |
organism-sequence
|
|
PR:O15519-9 |
CASP8 and FADD-like apoptosis regulator isoform h9 (human)
|
hCFLAR/iso:h9
|
"A CASP8 and FADD-like apoptosis regulator (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O15519-9." [PRO:DNx, UniProtKB:O15519]
|
|
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|
| | | | | | | | |
| |
organism-modification
|
|
PR:000081836 |
CASP8 and FADD-like apoptosis regulator deaminated 1 (human)
|
hCFLAR/Deam:1
|
"A CASP8 and FADD-like apoptosis regulator (human) that has been deaminated on the residue at the position equivalent to Asn-200 of the amino acid sequence represented by UniProtKB:O15519-1. Example: UniProtKB:O15519-1, Asn-200, MOD:00684." [IEDB_epitope:1587251, PRO:DNx]
|
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| | | | | | |
| | | |
organism-gene
|
|
PR:O35732 |
CASP8 and FADD-like apoptosis regulator (mouse)
|
mCFLAR
|
"A CASP8 and FADD-like apoptosis regulator that is encoded in the genome of mouse." [OMA:O35732, PRO:DNx]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-sequence
|
|
PR:O35732-1 |
CASP8 and FADD-like apoptosis regulator isoform m1 (mouse)
|
mCFLAR/iso:m1
|
"A CASP8 and FADD-like apoptosis regulator (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O35732-1." [PRO:DNx, UniProtKB:O35732]
|
|
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| | | | | | | | |
| |
organism-sequence
|
|
PR:O35732-2 |
CASP8 and FADD-like apoptosis regulator isoform m2 (mouse)
|
mCFLAR/iso:m2
|
"A CASP8 and FADD-like apoptosis regulator (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O35732-2." [PRO:DNx, UniProtKB:O35732]
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gene
|
|
PR:000002310 |
caspase-10
|
CASP10
|
"A caspase-8-like protease that is a translation product of the human CASP10 gene or a 1:1 ortholog thereof." [PRO:WCB]
|
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|
| | | | | | |
| | | |
organism-gene
|
|
PR:Q92851 |
caspase-10 (human)
|
hCASP10
|
"A caspase-10 that is encoded in the genome of human." [PRO:WCB, UniProtKB:Q92851]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-sequence
|
|
PR:Q92851-1 |
caspase-10 isoform A (human)
|
hCASP10/iso:A
|
"A caspase-10 isoform 1 that is encoded in the genome of human." [PRO:JAN]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-sequence
|
|
PR:Q92851-2 |
caspase-10 isoform B (human)
|
hCASP10/iso:B
|
"A caspase-10 isoform 2 that is encoded in the genome of human." [PRO:JAN]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-sequence
|
|
PR:Q92851-3 |
caspase-10 isoform C (human)
|
hCASP10/iso:C
|
"A caspase-10 isoform 3 that is encoded in the genome of human." [PRO:JAN]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-sequence
|
|
PR:Q92851-4 |
caspase-10 isoform D (human)
|
hCASP10/iso:D
|
"A caspase-10 isoform 4 that is encoded in the genome of human." [PRO:JAN]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-sequence
|
|
PR:Q92851-5 |
caspase-10 isoform h5 (human)
|
hCASP10/iso:h5
|
"A caspase-10 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q92851-5." [PRO:DNx, UniProtKB:Q92851]
|
|
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| |
organism-sequence
|
|
PR:Q92851-6 |
caspase-10 isoform h6 (human)
|
hCASP10/iso:h6
|
"A caspase-10 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q92851-6." [PRO:DNx, UniProtKB:Q92851]
|
|
|
|
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|
|
| | | | | | | | |
| |
organism-sequence
|
|
PR:Q92851-7 |
caspase-10 isoform h7 (human)
|
hCASP10/iso:h7
|
"A caspase-10 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q92851-7." [PRO:DNx, UniProtKB:Q92851]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-modification
|
|
PR:000077727 |
caspase-10 phosphorylated 1 (human)
|
hCASP10/Phos:1
|
"A caspase-10 (human) that has been phosphorylated on the residue at the position equivalent to Ser-19 of the amino acid sequence represented by UniProtKB:Q92851-1. Example: UniProtKB:Q92851-1, Ser-19, MOD:00046." [IEDB_epitope:2147415, PRO:DNx]
|
|
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|
| | | | | | |
| | | |
sequence
|
|
PR:000002396 |
caspase-10 isoform 1
|
CASP10/iso:1
|
"A caspase-10 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q92851-1 or a 1:1 ortholog thereof." [PRO:JAN]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-sequence
|
|
PR:Q92851-1 |
caspase-10 isoform A (human)
|
hCASP10/iso:A
|
"A caspase-10 isoform 1 that is encoded in the genome of human." [PRO:JAN]
|
|
|
|
|
|
|
| | | | | | |
| | | |
sequence
|
|
PR:000002397 |
caspase-10 isoform 2
|
CASP10/iso:2
|
"A caspase-10 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q92851-2 or a 1:1 ortholog thereof." [PRO:JAN]
|
|
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| | | | | | | | |
| |
organism-sequence
|
|
PR:Q92851-2 |
caspase-10 isoform B (human)
|
hCASP10/iso:B
|
"A caspase-10 isoform 2 that is encoded in the genome of human." [PRO:JAN]
|
|
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|
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| | | | | | |
| | | |
sequence
|
|
PR:000002398 |
caspase-10 isoform 3
|
CASP10/iso:3
|
"A caspase-10 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q92851-3 or a 1:1 ortholog thereof." [PRO:JAN]
|
|
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|
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| | | | | | | | |
| |
organism-sequence
|
|
PR:Q92851-3 |
caspase-10 isoform C (human)
|
hCASP10/iso:C
|
"A caspase-10 isoform 3 that is encoded in the genome of human." [PRO:JAN]
|
|
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|
|
|
|
| | | | | | |
| | | |
sequence
|
|
PR:000002399 |
caspase-10 isoform 4
|
CASP10/iso:4
|
"A caspase-10 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q92851-4 or a 1:1 ortholog thereof." [PRO:JAN]
|
|
|
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|
|
|
| | | | | | | | |
| |
organism-sequence
|
|
PR:Q92851-4 |
caspase-10 isoform D (human)
|
hCASP10/iso:D
|
"A caspase-10 isoform 4 that is encoded in the genome of human." [PRO:JAN]
|
|
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|
| | | | | | |
| | | |
modification
|
|
PR:000018759 |
caspase-10 proteolytic cleavage product
|
CASP10/ClvPrd
|
"A caspase-10 that has been processed by proteolytic cleavage." [PRO:DNx]
|
|
|
|
|
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|
| | | | |
| | | | | |
gene
|
|
PR:000002317 |
caspase-8
|
CASP8
|
"A caspase-8-like protease that is a translation product of the human CASP8 gene or a 1:1 ortholog thereof." [PRO:WCB]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-gene
|
|
PR:O89110 |
caspase-8 (mouse)
|
mCASP8
|
"A caspase-8 that is encoded in the genome of mouse." [OMA:O89110, PRO:DNx]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-sequence
|
|
PR:O89110-1 |
caspase-8 isoform 1 (mouse)
|
mCASP8/iso:1
|
"A caspase-8 isoform 1 that is encoded in the genome of mouse." [PRO:JAN]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-gene
|
|
PR:Q14790 |
caspase-8 (human)
|
hCASP8
|
"A caspase-8 that is encoded in the genome of human." [PRO:DNx]
|
|
Yes |
|
|
|
|
| | | | | | | | |
| |
organism-sequence
|
|
PR:Q14790-1 |
caspase-8 isoform 1 (human)
|
hCASP8/iso:1
|
"A caspase-8 isoform 1 that is encoded in the genome of human." [PRO:JAN]
|
|
|
|
|
|
|
| | | | | | | | | | |
organism-modification
|
|
PR:000036063 |
caspase-8 isoform 1 cleaved 1 (human)
|
hCASP8/iso:1/Clv:1
|
"A caspase-8 isoform 1 cleaved 1 in human. UniProtKB:Q14790-1, 217-374." [PMID:9184224, PRO:CNA]
|
|
Yes |
|
|
|
|
| | | | | | | | | | |
organism-modification
|
|
PR:000036065 |
caspase-8 isoform 1 cleaved 2 (human)
|
hCASP8/iso:1/Clv:2
|
"A caspase-8 isoform 1 cleaved 2 in human. UniProtKB:Q14790-1, 385-479." [PMID:9184224, PRO:CNA]
|
|
Yes |
|
|
|
|
| | | | | | | | |
| |
organism-sequence
|
|
PR:Q14790-2 |
caspase-8 isoform 2 (human)
|
hCASP8/iso:2
|
"A caspase-8 isoform 2 that is encoded in the genome of human." [PRO:JAN]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-sequence
|
|
PR:Q14790-3 |
caspase-8 isoform 3 (human)
|
hCASP8/iso:3
|
"A caspase-8 isoform 3 that is encoded in the genome of human." [PRO:JAN]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-sequence
|
|
PR:Q14790-4 |
caspase-8 isoform 4 (human)
|
hCASP8/iso:4
|
"A caspase-8 isoform 4 that is encoded in the genome of human." [PRO:JAN]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-sequence
|
|
PR:Q14790-5 |
caspase-8 isoform 5 (human)
|
hCASP8/iso:5
|
"A caspase-8 isoform 5 that is encoded in the genome of human." [PRO:JAN]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-sequence
|
|
PR:Q14790-6 |
caspase-8 isoform 6 (human)
|
hCASP8/iso:6
|
"A caspase-8 isoform 6 that is encoded in the genome of human." [PRO:JAN]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-sequence
|
|
PR:Q14790-7 |
caspase-8 isoform 7 (human)
|
hCASP8/iso:7
|
"A caspase-8 isoform 7 that is encoded in the genome of human." [PRO:JAN]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-sequence
|
|
PR:Q14790-8 |
caspase-8 isoform 8 (human)
|
hCASP8/iso:8
|
"A caspase-8 isoform 8 that is encoded in the genome of human." [PRO:JAN]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-sequence
|
|
PR:Q14790-9 |
caspase-8 isoform 9 (human)
|
hCASP8/iso:9
|
"A caspase-8 isoform 9 that is encoded in the genome of human." [PRO:JAN]
|
|
|
|
|
|
|
| | | | | | | | |
| |
organism-modification
|
|
PR:000045931 |
caspase-8 phosphorylated 1 (human)
|
hCASP8/Phos:1
|
"A caspase-8 (human) that has been phosphorylated on the residue at the position equivalent to Tyr-380 of the amino acid sequence represented by UniProtKB:Q14790-1. Example: UniProtKB:Q14790-1, Tyr-380, MOD:00048." [iPTMnet:Q14790, PMID:16619028, PMID:19851329]
|
|
|
|
|
|
|
| | | | | | |
| | | |
organism-gene
|
|
PR:Q9JHX4 |
caspase-8 (rat)
|
rCASP8
|
"A caspase-8 that is encoded in the genome of rat." [OMA:Q9JHX4, PRO:DNx]
|
|
|
|
|
|
|
| | | | | | |
| | | |
sequence
|
|
PR:000002412 |
caspase-8 isoform 1
|
CASP8/iso:1
|
"A caspase-8 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q14790-1 or a 1:1 ortholog thereof." [PRO:JAN]
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organism-sequence
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PR:O89110-1 |
caspase-8 isoform 1 (mouse)
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mCASP8/iso:1
|
"A caspase-8 isoform 1 that is encoded in the genome of mouse." [PRO:JAN]
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organism-sequence
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PR:Q14790-1 |
caspase-8 isoform 1 (human)
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hCASP8/iso:1
|
"A caspase-8 isoform 1 that is encoded in the genome of human." [PRO:JAN]
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organism-modification
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PR:000036063 |
caspase-8 isoform 1 cleaved 1 (human)
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hCASP8/iso:1/Clv:1
|
"A caspase-8 isoform 1 cleaved 1 in human. UniProtKB:Q14790-1, 217-374." [PMID:9184224, PRO:CNA]
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Yes |
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organism-modification
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PR:000036065 |
caspase-8 isoform 1 cleaved 2 (human)
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hCASP8/iso:1/Clv:2
|
"A caspase-8 isoform 1 cleaved 2 in human. UniProtKB:Q14790-1, 385-479." [PMID:9184224, PRO:CNA]
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Yes |
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modification
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PR:000036062 |
caspase-8 isoform 1 cleaved 1
|
CASP8/iso:1/Clv:1
|
"A caspase-8 isoform 1 that has been processed by proteolytic cleavage to yield the mature caspase-8 subunit p18." [PRO:CNA]
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organism-modification
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PR:000036063 |
caspase-8 isoform 1 cleaved 1 (human)
|
hCASP8/iso:1/Clv:1
|
"A caspase-8 isoform 1 cleaved 1 in human. UniProtKB:Q14790-1, 217-374." [PMID:9184224, PRO:CNA]
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Yes |
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| |
modification
|
|
PR:000036064 |
caspase-8 isoform 1 cleaved 2
|
CASP8/iso:1/Clv:2
|
"A caspase-8 isoform 1 that has been processed by proteolytic cleavage to yield the mature caspase-8 subunit p10." [PRO:CNA]
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organism-modification
|
|
PR:000036065 |
caspase-8 isoform 1 cleaved 2 (human)
|
hCASP8/iso:1/Clv:2
|
"A caspase-8 isoform 1 cleaved 2 in human. UniProtKB:Q14790-1, 385-479." [PMID:9184224, PRO:CNA]
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Yes |
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sequence
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|
PR:000002413 |
caspase-8 isoform 2
|
CASP8/iso:2
|
"A caspase-8 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q14790-2 or a 1:1 ortholog thereof." [PRO:JAN]
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organism-sequence
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PR:Q14790-2 |
caspase-8 isoform 2 (human)
|
hCASP8/iso:2
|
"A caspase-8 isoform 2 that is encoded in the genome of human." [PRO:JAN]
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sequence
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PR:000002414 |
caspase-8 isoform 3
|
CASP8/iso:3
|
"A caspase-8 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q14790-3 or a 1:1 ortholog thereof." [PRO:JAN]
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organism-sequence
|
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PR:Q14790-3 |
caspase-8 isoform 3 (human)
|
hCASP8/iso:3
|
"A caspase-8 isoform 3 that is encoded in the genome of human." [PRO:JAN]
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sequence
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PR:000002415 |
caspase-8 isoform 4
|
CASP8/iso:4
|
"A caspase-8 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q14790-4 or a 1:1 ortholog thereof." [PRO:JAN]
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organism-sequence
|
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PR:Q14790-4 |
caspase-8 isoform 4 (human)
|
hCASP8/iso:4
|
"A caspase-8 isoform 4 that is encoded in the genome of human." [PRO:JAN]
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sequence
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PR:000002416 |
caspase-8 isoform 5
|
CASP8/iso:5
|
"A caspase-8 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q14790-5 or a 1:1 ortholog thereof." [PRO:JAN]
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organism-sequence
|
|
PR:Q14790-5 |
caspase-8 isoform 5 (human)
|
hCASP8/iso:5
|
"A caspase-8 isoform 5 that is encoded in the genome of human." [PRO:JAN]
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sequence
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|
PR:000002417 |
caspase-8 isoform 6
|
CASP8/iso:6
|
"A caspase-8 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q14790-6 or a 1:1 ortholog thereof." [PRO:JAN]
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| |
organism-sequence
|
|
PR:Q14790-6 |
caspase-8 isoform 6 (human)
|
hCASP8/iso:6
|
"A caspase-8 isoform 6 that is encoded in the genome of human." [PRO:JAN]
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sequence
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PR:000002418 |
caspase-8 isoform 7
|
CASP8/iso:7
|
"A caspase-8 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q14790-7 or a 1:1 ortholog thereof." [PRO:JAN]
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| | | | | | | | |
| |
organism-sequence
|
|
PR:Q14790-7 |
caspase-8 isoform 7 (human)
|
hCASP8/iso:7
|
"A caspase-8 isoform 7 that is encoded in the genome of human." [PRO:JAN]
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| | | |
sequence
|
|
PR:000002419 |
caspase-8 isoform 8
|
CASP8/iso:8
|
"A caspase-8 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q14790-8 or a 1:1 ortholog thereof." [PRO:JAN]
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| |
organism-sequence
|
|
PR:Q14790-8 |
caspase-8 isoform 8 (human)
|
hCASP8/iso:8
|
"A caspase-8 isoform 8 that is encoded in the genome of human." [PRO:JAN]
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| | | |
sequence
|
|
PR:000002420 |
caspase-8 isoform 9
|
CASP8/iso:9
|
"A caspase-8 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q14790-9 or a 1:1 ortholog thereof." [PRO:JAN]
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| | | | | | | | |
| |
organism-sequence
|
|
PR:Q14790-9 |
caspase-8 isoform 9 (human)
|
hCASP8/iso:9
|
"A caspase-8 isoform 9 that is encoded in the genome of human." [PRO:JAN]
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| | | | | | |
| | | |
modification
|
|
PR:000018768 |
caspase-8 proteolytic cleavage product
|
CASP8/ClvPrd
|
"A caspase-8 that has been processed by proteolytic cleavage." [PRO:DNx]
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| | | | | | | | |
| |
modification
|
|
PR:000036062 |
caspase-8 isoform 1 cleaved 1
|
CASP8/iso:1/Clv:1
|
"A caspase-8 isoform 1 that has been processed by proteolytic cleavage to yield the mature caspase-8 subunit p18." [PRO:CNA]
|
|
|
|
|
|
|
| | | | | | | | | | |
organism-modification
|
|
PR:000036063 |
caspase-8 isoform 1 cleaved 1 (human)
|
hCASP8/iso:1/Clv:1
|
"A caspase-8 isoform 1 cleaved 1 in human. UniProtKB:Q14790-1, 217-374." [PMID:9184224, PRO:CNA]
|
|
Yes |
|
|
|
|
| | | | | | | | |
| |
modification
|
|
PR:000036064 |
caspase-8 isoform 1 cleaved 2
|
CASP8/iso:1/Clv:2
|
"A caspase-8 isoform 1 that has been processed by proteolytic cleavage to yield the mature caspase-8 subunit p10." [PRO:CNA]
|
|
|
|
|
|
|
| | | | | | | | | | |
organism-modification
|
|
PR:000036065 |
caspase-8 isoform 1 cleaved 2 (human)
|
hCASP8/iso:1/Clv:2
|
"A caspase-8 isoform 1 cleaved 2 in human. UniProtKB:Q14790-1, 385-479." [PMID:9184224, PRO:CNA]
|
|
Yes |
|
|
