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Protein Ontology report - cellular tumor antigen p53 isoform 1
PR:000003036 - http://purl.obolibrary.org/obo/PR_000003036
 
  Protein Forms  Complex  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000003036   
  PRO namecellular tumor antigen p53 isoform 1 
  Synonyms
PRO-Short-label: EXACT:TP53/iso:1
  Definition"A cellular tumor antigen p53 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P04637-1 or a 1:1 ortholog thereof." [PRO:CNA] 
  PRO Categorysequence 
  ParentPR:000003035 cellular tumor antigen p53
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Sequence1                                                  Organism-Sequence 1                                        
         Modification23                                                  Organism-Modification 22                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

Comp. In Complex?
sequence


PR:000003036 cellular tumor antigen p53 isoform 1
TP53/iso:1

organism-sequence


PR:P04637-1 cellular tumor antigen p53 isoform 1 (human)
hTP53/iso:1
Yes
organism-modification


PR:000027764 cellular tumor antigen p53 isoform 1 phosphorylated 3 (human)
hTP53/iso:1/Phos:3

organism-modification


PR:000027766 cellular tumor antigen p53 isoform 1 dimethylated 1 (human)
hTP53/iso:1/Me2:1
Yes
organism-modification


PR:000027768 cellular tumor antigen p53 isoform 1 phosphorylated 4 (human)
hTP53/iso:1/Phos:4

organism-modification


PR:000027770 cellular tumor antigen p53 isoform 1 phosphorylated 5 (human)
hTP53/iso:1/Phos:5

organism-modification


PR:000027772 cellular tumor antigen p53 isoform 1 phosphorylated 6 (human)
hTP53/iso:1/Phos:6

organism-modification


PR:000027774 cellular tumor antigen p53 isoform 1 acetylated 1 (human)
hTP53/iso:1/Ac:1
Yes
organism-modification


PR:000027806 cellular tumor antigen p53 isoform 1 ubiquitinated 1 (human)
hTP53/iso:1/Ubiq:1

organism-modification


PR:000027808 cellular tumor antigen p53 isoform 1 methylated 3 (human)
hTP53/iso:1/Me:3
Yes
organism-modification


PR:000027810 cellular tumor antigen p53 isoform 1 methylated 4 (human)
hTP53/iso:1/Me:4
Yes
organism-modification


PR:000027812 cellular tumor antigen p53 isoform 1 acetylated 2 (human)
hTP53/iso:1/Ac:2
Yes
organism-modification


PR:000027814 cellular tumor antigen p53 isoform 1 phosphorylated 12 (human)
hTP53/iso:1/Phos:12
Yes
organism-modification


PR:000027827 cellular tumor antigen p53 isoform 1 dimethylated 2 (human)
hTP53/iso:1/Me2:2

organism-modification


PR:000027829 cellular tumor antigen p53 isoform 1 phosphorylated 7 (human)
hTP53/iso:1/Phos:7

organism-modification


PR:000027831 cellular tumor antigen p53 isoform 1 phosphorylated 8 (human)
hTP53/iso:1/Phos:8

organism-modification


PR:000027833 cellular tumor antigen p53 isoform 1 phosphorylated 9 (human)
hTP53/iso:1/Phos:9
Yes
organism-modification


PR:000027835 cellular tumor antigen p53 isoform 1 O-glycosylated 1 (human)
hTP53/iso:1/OGlyco:1

organism-modification


PR:000027837 cellular tumor antigen p53 isoform 1 phosphorylated 10 (human)
hTP53/iso:1/Phos:10

organism-modification


PR:000027839 cellular tumor antigen p53 isoform 1 phosphorylated 11 (human)
hTP53/iso:1/Phos:11
Yes
organism-modification


PR:000027841 cellular tumor antigen p53 isoform 1 sumoylated 1 (human)
hTP53/iso:1/Sumo:1

Yes
organism-modification


PR:000027846 cellular tumor antigen p53 isoform 1 unmodified form (human)
hTP53/iso:1/UnMod

Yes
organism-modification


PR:000035446 cellular tumor antigen p53 isoform 1 phosphorylated 1 (human)
hTP53/iso:1/Phos:1
Yes
organism-modification


PR:000036624 cellular tumor antigen p53 isoform 1 phosphorylated 2 (human)
hTP53/iso:1/Phos:2
Yes
modification


PR:000003037 cellular tumor antigen p53 isoform 1 unmodified form
TP53/iso:1/UnMod

organism-modification


PR:000027846 cellular tumor antigen p53 isoform 1 unmodified form (human)
hTP53/iso:1/UnMod

Yes
modification


PR:000003038 cellular tumor antigen p53 isoform 1 phosphorylated form
TP53/iso:1/PhosRes+

modification


PR:000003039 cellular tumor antigen p53 isoform 1 phosphorylated 1
TP53/iso:1/Phos:1

organism-modification


PR:000035446 cellular tumor antigen p53 isoform 1 phosphorylated 1 (human)
hTP53/iso:1/Phos:1
Yes
modification


PR:000003040 cellular tumor antigen p53 isoform 1 phosphorylated 2
TP53/iso:1/Phos:2

organism-modification


PR:000036624 cellular tumor antigen p53 isoform 1 phosphorylated 2 (human)
hTP53/iso:1/Phos:2
Yes
modification


PR:000027763 cellular tumor antigen p53 isoform 1 phosphorylated 3
TP53/iso:1/Phos:3

organism-modification


PR:000027764 cellular tumor antigen p53 isoform 1 phosphorylated 3 (human)
hTP53/iso:1/Phos:3

modification


PR:000027767 cellular tumor antigen p53 isoform 1 phosphorylated 4
TP53/iso:1/Phos:4

organism-modification


PR:000027768 cellular tumor antigen p53 isoform 1 phosphorylated 4 (human)
hTP53/iso:1/Phos:4

modification


PR:000027769 cellular tumor antigen p53 isoform 1 phosphorylated 5
TP53/iso:1/Phos:5

organism-modification


PR:000027770 cellular tumor antigen p53 isoform 1 phosphorylated 5 (human)
hTP53/iso:1/Phos:5

modification


PR:000027771 cellular tumor antigen p53 isoform 1 phosphorylated 6
TP53/iso:1/Phos:6

organism-modification


PR:000027772 cellular tumor antigen p53 isoform 1 phosphorylated 6 (human)
hTP53/iso:1/Phos:6

modification


PR:000027813 cellular tumor antigen p53 isoform 1 phosphorylated 12
TP53/iso:1/Phos:12

organism-modification


PR:000027814 cellular tumor antigen p53 isoform 1 phosphorylated 12 (human)
hTP53/iso:1/Phos:12
Yes
modification


PR:000027828 cellular tumor antigen p53 isoform 1 phosphorylated 7
TP53/iso:1/Phos:7

organism-modification


PR:000027829 cellular tumor antigen p53 isoform 1 phosphorylated 7 (human)
hTP53/iso:1/Phos:7

modification


PR:000027830 cellular tumor antigen p53 isoform 1 phosphorylated 8
TP53/iso:1/Phos:8

organism-modification


PR:000027831 cellular tumor antigen p53 isoform 1 phosphorylated 8 (human)
hTP53/iso:1/Phos:8

modification


PR:000027832 cellular tumor antigen p53 isoform 1 phosphorylated 9
TP53/iso:1/Phos:9

organism-modification


PR:000027833 cellular tumor antigen p53 isoform 1 phosphorylated 9 (human)
hTP53/iso:1/Phos:9
Yes
modification


PR:000027836 cellular tumor antigen p53 isoform 1 phosphorylated 10
TP53/iso:1/Phos:10

organism-modification


PR:000027837 cellular tumor antigen p53 isoform 1 phosphorylated 10 (human)
hTP53/iso:1/Phos:10

modification


PR:000027838 cellular tumor antigen p53 isoform 1 phosphorylated 11
TP53/iso:1/Phos:11

organism-modification


PR:000027839 cellular tumor antigen p53 isoform 1 phosphorylated 11 (human)
hTP53/iso:1/Phos:11
Yes
modification


PR:000027765 cellular tumor antigen p53 isoform 1 dimethylated 1
TP53/iso:1/Me2:1

organism-modification


PR:000027766 cellular tumor antigen p53 isoform 1 dimethylated 1 (human)
hTP53/iso:1/Me2:1
Yes
modification


PR:000027773 cellular tumor antigen p53 isoform 1 acetylated 1
TP53/iso:1/Ac:1

organism-modification


PR:000027774 cellular tumor antigen p53 isoform 1 acetylated 1 (human)
hTP53/iso:1/Ac:1
Yes
modification


PR:000027805 cellular tumor antigen p53 isoform 1 ubiquitinated 1
TP53/iso:1/Ubiq:1

organism-modification


PR:000027806 cellular tumor antigen p53 isoform 1 ubiquitinated 1 (human)
hTP53/iso:1/Ubiq:1

modification


PR:000027807 cellular tumor antigen p53 isoform 1 methylated 3
TP53/iso:1/Me:3

organism-modification


PR:000027808 cellular tumor antigen p53 isoform 1 methylated 3 (human)
hTP53/iso:1/Me:3
Yes
modification


PR:000027809 cellular tumor antigen p53 isoform 1 methylated 4
TP53/iso:1/Me:4

organism-modification


PR:000027810 cellular tumor antigen p53 isoform 1 methylated 4 (human)
hTP53/iso:1/Me:4
Yes
modification


PR:000027811 cellular tumor antigen p53 isoform 1 acetylated 2
TP53/iso:1/Ac:2

organism-modification


PR:000027812 cellular tumor antigen p53 isoform 1 acetylated 2 (human)
hTP53/iso:1/Ac:2
Yes
modification


PR:000027826 cellular tumor antigen p53 isoform 1 dimethylated 2
TP53/iso:1/Me2:2

organism-modification


PR:000027827 cellular tumor antigen p53 isoform 1 dimethylated 2 (human)
hTP53/iso:1/Me2:2

modification


PR:000027834 cellular tumor antigen p53 isoform 1 O-glycosylated 1
TP53/iso:1/OGlyco:1

organism-modification


PR:000027835 cellular tumor antigen p53 isoform 1 O-glycosylated 1 (human)
hTP53/iso:1/OGlyco:1

modification


PR:000027840 cellular tumor antigen p53 isoform 1 sumoylated 1
TP53/iso:1/Sumo:1

organism-modification


PR:000027841 cellular tumor antigen p53 isoform 1 sumoylated 1 (human)
hTP53/iso:1/Sumo:1

Yes
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TP53/iso:1 forms found in complexes   

TP53/iso:1 Component
 Complexes
PR:000027841 hTP53/iso:1/Sumo:1 PR:000027844 p53 complex sumoylated 1 (human)
PR:000027846 hTP53/iso:1/UnMod PR:000027844 p53 complex sumoylated 1 (human)
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000027766 hTP53/iso:1/Me2:1
UniProtKB:P04637-1, Lys-382, MOD:00084		 enablesGO:0005515 protein binding with PR:Q12888 53BP1 (human) PMID:18840612
PR:000027774 hTP53/iso:1/Ac:1
UniProtKB:P04637-1, Lys-120, MOD:00064		 acts_upstream_of_or_withinGO:0043065 positive regulation of apoptotic process PMID:17189187
PR:000027808 hTP53/iso:1/Me:3
UniProtKB:P04637-1, Lys-372, MOD:00663		 acts_upstream_of_or_withinGO:0045893 positive regulation of DNA-templated transcription PMID:15525938
located_inGO:0005634 nucleus PMID:15525938
PR:000027810 hTP53/iso:1/Me:4
UniProtKB:P04637-1, Lys-370, MOD:00663		 acts_upstream_of_or_withinGO:0045892 negative regulation of DNA-templated transcription PMID:17108971
PR:000027812 hTP53/iso:1/Ac:2
UniProtKB:P04637-1, Lys-382, MOD:00064		 acts_upstream_of_or_withinGO:0045893 positive regulation of DNA-templated transcription PMID:20228809
PR:000027814 hTP53/iso:1/Phos:12
UniProtKB:P04637-1, Ser-15/Ser-392, MOD:00046		 acts_upstream_of_or_withinGO:0045893 positive regulation of DNA-templated transcription PMID:21317932
located_inGO:0005634 nucleus PMID:21317932
PR:000027833 hTP53/iso:1/Phos:9
UniProtKB:P04637-1, Ser-15/Ser-37, MOD:00046		 acts_upstream_of_or_withinGO:0010468 regulation of gene expression PMID:14712210
PR:000027839 hTP53/iso:1/Phos:11
UniProtKB:P04637-1, Ser-183/Ser-269, MOD:00046|Thr-284, MOD:00047		 acts_upstream_of_or_withinGO:0010629 negative regulation of gene expression PMID:20959462
PR:000035446 hTP53/iso:1/Phos:1
UniProtKB:P04637-1, Ser-15, MOD:00046		 acts_upstream_of_or_withinGO:0006915 apoptotic process PMID:11602639
located_inGO:0005634 nucleus PMID:11602639
PR:000036624 hTP53/iso:1/Phos:2
UniProtKB:P04637-1, Ser-15/Ser-46, MOD:00046		 acts_upstream_of_or_withinGO:0006915 apoptotic process PMID:15642743
enablesGO:0005515 protein binding with PR:000003109 MAPK p38 active form PMID:15642743
PR:P04637-1 hTP53/iso:1 enablesGO:0005515 protein binding with PR:O43683 BUB1 PMID:17671183
GO:0005515 protein binding with PR:O60566 BUB1B PMID:17671183