back to PRO homepage
  Home |   Linked Open Data |   Browse |  
Search

 |   Statistics |   Download
 RACE-PRO
 PRO tracker
 Community
 PRO Consortium
 Publications
 Documentation

Protein Ontology report - cellular tumor antigen p53 isoform 1 methylated 3
PR:000027807 - http://purl.obolibrary.org/obo/PR_000027807
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000027807   
  PRO namecellular tumor antigen p53 isoform 1 methylated 3 
  Synonyms
PRO-Short-label: EXACT:TP53/iso:1/Me:3
  Definition"A cellular tumor antigen p53 isoform 1 that has been methylated at the second Lys residue of the [KR]-[STA]-K motif within the C-terminal regulatory region. Example: UniProtKB:P04637-1, Lys-372, MOD:00663." [PMID:15525938, PRO:PD] 
  PRO Categorymodification 
  ParentPR:000003036 cellular tumor antigen p53 isoform 1
PR:000037074 methylated protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Modification1                                                  Organism-Modification 1                                        
  Term Hierarchy
  Visualization
DAG: OLS:
Back to top
Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Ann. Has Annotation?

Comp. In Complex?
modification


PR:000027807 cellular tumor antigen p53 isoform 1 methylated 3, TP53/iso:1/Me:3

organism-modification


PR:000027808 cellular tumor antigen p53 isoform 1 methylated 3 (human), hTP53/iso:1/Me:3
Yes
Back to top
Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000027808 hTP53/iso:1/Me:3
UniProtKB:P04637-1, Lys-372, MOD:00663 | p53-mLys372
"A cellular tumor antigen p53 isoform 1 methylated 3 in human. This modification promotes p53 stability and inhibits Smyd2 mediated p53 methylation at Lys-370. UniProtKB:P04637-1, Lys-372, MOD:00663." [PMID:15525938, PRO:PD]		 acts_upstream_of_or_withinGO:0045893 positive regulation of DNA-templated transcription PMID:15525938
located_inGO:0005634 nucleus PMID:15525938