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sequence
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PR:000003091 |
cyclin-dependent kinase inhibitor 1B isoform 1
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CDKN1B/iso:1
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"A cyclin-dependent kinase inhibitor 1B that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P46527-1 or a 1:1 ortholog thereof." [PRO:CNA]
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organism-sequence
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PR:P46414-1 |
cyclin-dependent kinase inhibitor 1B isoform 1 (mouse)
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mCDKN1B/iso:1
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"A cyclin-dependent kinase inhibitor 1B isoform 1 that is encoded in the genome of mouse." [PRO:CNA]
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organism-sequence
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PR:P46527-1 |
cyclin-dependent kinase inhibitor 1B isoform 1 (human)
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hCDKN1B/iso:1
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"A cyclin-dependent kinase inhibitor 1B isoform 1 that is encoded in the genome of human." [PRO:CNA]
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organism-modification
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PR:000025750 |
cyclin-dependent kinase inhibitor 1B isoform 1 phosphorylated 2 (human)
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hCDKN1B/iso:1/Phos:2
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"A cyclin-dependent kinase inhibitor 1B isoform 1 phosphorylated 2 in human. Phosphorylation at this site promotes subsequent Cdk2-mediated phosphorylation at Thr-187. UniProtKB:P46527-1, Tyr-88, MOD:00048." [PMID:17254966, PRO:JAN]
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Yes |
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organism-modification
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PR:000025752 |
cyclin-dependent kinase inhibitor 1B isoform 1 phosphorylated 3 (human)
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hCDKN1B/iso:1/Phos:3
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"A cyclin-dependent kinase inhibitor 1B isoform 1 phosphorylated 3 in human. UniProtKB:P46527-1, Tyr-88, MOD:00048|Thr-187, MOD:00047." [PMID:17254966, PRO:CNA]
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organism-modification
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PR:000036634 |
cyclin-dependent kinase inhibitor 1B isoform 1 phosphorylated 1 (human)
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hCDKN1B/iso:1/Phos:1
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"A cyclin-dependent kinase inhibitor 1B isoform 1 phosphorylated 1 in human. UniProtKB:P46527-1, Thr-157, MOD:00047." [PMID:12244301, PMID:15057270, PRO:JAN]
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Yes |
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organism-modification
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PR:000045370 |
cyclin-dependent kinase inhibitor 1B isoform 1 unphosphorylated 2 (human)
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hCDKN1B/iso:1/UnPhos:2
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"A cyclin-dependent kinase inhibitor 1B isoform 1 (human) that lacks phosphorylation at Tyr-88. UniProtKB:P46527-1, Tyr-88, PR:000026291." [PRO:CNA]
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Yes |
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modification
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PR:000003092 |
cyclin-dependent kinase inhibitor 1B isoform 1 unmodified form
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CDKN1B/iso:1/UnMod
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"A cyclin-dependent kinase inhibitor 1B isoform 1 that has not been subjected to any co- or post-translational residue modification or peptide bond cleavage." [PRO:JAN]
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modification
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PR:000003093 |
cyclin-dependent kinase inhibitor 1B isoform 1 phosphorylated form
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CDKN1B/iso:1/PhosRes+
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"A cyclin-dependent kinase inhibitor 1B isoform 1 that includes at least one phosphorylated residue." [PRO:CNA]
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modification
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PR:000003094 |
cyclin-dependent kinase inhibitor 1B isoform 1 phosphorylated 1
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CDKN1B/iso:1/Phos:1
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"A cyclin-dependent kinase inhibitor 1B isoform 1 phosphorylated form in which the phosphorylation occurs within the nuclear localization sequence (NLS)." [PMID:15057270, PRO:JAN]
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organism-modification
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PR:000036634 |
cyclin-dependent kinase inhibitor 1B isoform 1 phosphorylated 1 (human)
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hCDKN1B/iso:1/Phos:1
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"A cyclin-dependent kinase inhibitor 1B isoform 1 phosphorylated 1 in human. UniProtKB:P46527-1, Thr-157, MOD:00047." [PMID:12244301, PMID:15057270, PRO:JAN]
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Yes |
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modification
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PR:000025749 |
cyclin-dependent kinase inhibitor 1B isoform 1 phosphorylated 2
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CDKN1B/iso:1/Phos:2
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"A cyclin-dependent kinase inhibitor 1B isoform 1 phosphorylated form in which the phosphorylation occurs at a conserved Tyr residue that is major phosphoacceptor site in the Cdk-binding domain. Example: UniProtKB:P46527-1, Tyr-88, MOD:00048." [PMID:17254966, PRO:DAN, PRO:JAN]
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organism-modification
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PR:000025750 |
cyclin-dependent kinase inhibitor 1B isoform 1 phosphorylated 2 (human)
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hCDKN1B/iso:1/Phos:2
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"A cyclin-dependent kinase inhibitor 1B isoform 1 phosphorylated 2 in human. Phosphorylation at this site promotes subsequent Cdk2-mediated phosphorylation at Thr-187. UniProtKB:P46527-1, Tyr-88, MOD:00048." [PMID:17254966, PRO:JAN]
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Yes |
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modification
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PR:000025751 |
cyclin-dependent kinase inhibitor 1B isoform 1 phosphorylated 3
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CDKN1B/iso:1/Phos:3
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"A cyclin-dependent kinase inhibitor 1B isoform 1 phosphorylated form in which the phosphorylation occurs at a conserved Tyr residue that is major phosphoacceptor site in the Cdk-binding domain, and phosphorylated by CDK2 on a Thr residue in the C-terminal region. Phosphorylation by CDK2 promotes degradation by the SCF-Skp2 ubiquitin-proteasome pathway. Example: UniProtKB:P46527-1, Tyr-88, MOD:00048|Thr-187, MOD:00047." [PMID:17254966, PRO:CNA, PRO:DAN]
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organism-modification
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PR:000025752 |
cyclin-dependent kinase inhibitor 1B isoform 1 phosphorylated 3 (human)
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hCDKN1B/iso:1/Phos:3
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"A cyclin-dependent kinase inhibitor 1B isoform 1 phosphorylated 3 in human. UniProtKB:P46527-1, Tyr-88, MOD:00048|Thr-187, MOD:00047." [PMID:17254966, PRO:CNA]
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