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Protein Ontology report - interferon regulatory factor 7 isoform 1 phosphorylated 1
PR:000003281 - http://purl.obolibrary.org/obo/PR_000003281
 
  Protein Forms  Complex      
Ontology Information Show OBO stanza
  PRO ID
PR:000003281   
  PRO nameinterferon regulatory factor 7 isoform 1 phosphorylated 1 
  Synonyms
PRO-Short-label: EXACT:IRF7/iso:1/Phos:1
Other: EXACT:IRF-7 active form | IRF-7 phosphorylated | phospho IRF7
  Definition"An interferon regulatory factor 7 isoform 1 phosphorylated form that has been activated by phosphorylation on the Ser residues located in the C-terminal region. Phosphorylation stimulates the C-terminal autoinhibitory domain to attain a highly extended conformation triggering dimerization through extensive contacts to a second subunit. Example: UniProtKB:Q92985-1, Ser-477/Ser-479, MOD:00046." [PMID:10893229, PMID:14517278, PMID:20043992, TLR:AMM] 
  CommentRequested by=TLR. 
  PRO Categorymodification 
  ParentPR:000003280 interferon regulatory factor 7 isoform 1 phosphorylated form
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Modification1                                                  Organism-Modification 1                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

Comp. In Complex?
modification


PR:000003281
interferon regulatory factor 7 isoform 1 phosphorylated 1
IRF7/iso:1/Phos:1
"An interferon regulatory factor 7 isoform 1 phosphorylated form that has been activated by phosphorylation on the Ser residues located in the C-terminal region. Phosphorylation stimulates the C-terminal autoinhibitory domain to attain a highly extended conformation triggering dimerization through extensive contacts to a second subunit. Example: UniProtKB:Q92985-1, Ser-477/Ser-479, MOD:00046." [PMID:10893229, PMID:14517278, PMID:20043992, TLR:AMM]

organism-modification


PR:000027082
interferon regulatory factor 7 isoform 1 phosphorylated 1 (human)
hIRF7/iso:1/Phos:1
"An interferon regulatory factor 7 isoform 1 phosphorylated 1 in human. UniProtKB:Q92985-1, Ser-477/Ser-479, MOD:00046." [PMID:10893229, PMID:14517278, TLR:AMM]

Yes
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IRF7/iso:1/Phos:1 forms found in complexes   

IRF7/iso:1/Phos:1 Component
 Complexes
PR:000027082 hIRF7/iso:1/Phos:1 PR:000027084 IRF3-P:IRF7-P complex (human)
PR:000027086 IRF7-P:IRF7-P complex (human)