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PRO ID
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| PRO name | interferon regulatory factor 7 isoform 1 phosphorylated 1 |
| Synonyms | | PRO-Short-label: | EXACT: | IRF7/iso:1/Phos:1 | | Other: | EXACT: | IRF-7 active form | IRF-7 phosphorylated | phospho IRF7 |
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| Definition | "An interferon regulatory factor 7 isoform 1 phosphorylated form that has been activated by phosphorylation on the Ser residues located in the C-terminal region. Phosphorylation stimulates the C-terminal autoinhibitory domain to attain a highly extended conformation triggering dimerization through extensive contacts to a second subunit. Example: UniProtKB:Q92985-1, Ser-477/Ser-479, MOD:00046." [PMID:10893229, PMID:14517278, PMID:20043992, TLR:AMM] |
| Comment | Requested by=TLR. |
| PRO Category | modification |
| Parent | PR:000003280 interferon regulatory factor 7 isoform 1 phosphorylated form
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| Terms by PRO Category |
| Organism-Independent |
Organism-Specific |
| Category |
Number of Terms |
Category |
Number of Terms | | Modification | 1 |
Organism-Modification |
1 | | | |
Term Hierarchy
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