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Protein Ontology report - amyloid-beta precursor protein
PR:000004168 - http://purl.obolibrary.org/obo/PR_000004168
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000004168   
  PRO nameamyloid-beta precursor protein 
  Synonyms
PRO-Short-label: EXACT:APP
Gene-based: RELATED:A4 | AD1
Other: EXACT:ABPP | AG | alzheimer disease amyloid A4 protein homolog | alzheimer disease amyloid protein | amyloid beta A4 protein | amyloid precursor protein | amyloid-beta (A4) precursor protein | amyloid-beta A4 protein | amyloidogenic glycoprotein | APPI | cerebral vascular amyloid peptide | CVAP | PN-II | PreA4 | protease nexin-II
  Definition"A protein that is a translation product of the human APP gene or a 1:1 ortholog thereof." [PRO:DNx] 
  CommentRequested by=Alzforum. 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 4                                        
         Sequence10                                                  Organism-Sequence 79                                        
         Modification27                                                  Organism-Modification 24                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000004168 amyloid-beta precursor protein
APP

organism-gene


PR:P05067 amyloid-beta precursor protein (human)
hAPP

organism-sequence


PR:000025558 amyloid-beta precursor protein sequence variant (human)
hAPP/var+

organism-sequence


PR:000025560 amyloid-beta precursor protein sequence variant D678N (human)
hAPP/var:D678N
Yes
organism-sequence


PR:000025561 amyloid-beta precursor protein sequence variant A692G (human)
hAPP/var:A692G
Yes
organism-sequence


PR:000025562 amyloid-beta precursor protein sequence variant E693G (human)
hAPP/var:E693G
Yes
organism-sequence


PR:000025563 amyloid-beta precursor protein sequence variant E693K (human)
hAPP/var:E693K
Yes
organism-sequence


PR:000025564 amyloid-beta precursor protein sequence variant E693Q (human)
hAPP/var:E693Q
Yes
organism-sequence


PR:000025565 amyloid-beta precursor protein sequence variant D694N (human)
hAPP/var:D694N
Yes
organism-sequence


PR:000025566 amyloid-beta precursor protein sequence variant L705V (human)
hAPP/var:L705V
Yes
organism-sequence


PR:000025567 amyloid-beta precursor protein sequence variant A713T (human)
hAPP/var:A713T
Yes
organism-sequence


PR:000025568 amyloid-beta precursor protein sequence variant T714A (human)
hAPP/var:T714A
Yes
organism-sequence


PR:000025569 amyloid-beta precursor protein sequence variant T714I (human)
hAPP/var:T714I
Yes
organism-sequence


PR:000025570 amyloid-beta precursor protein sequence variant V715M (human)
hAPP/var:V715M
Yes
organism-sequence


PR:000025571 amyloid-beta precursor protein sequence variant I716V (human)
hAPP/var:I716V
Yes
organism-sequence


PR:000025572 amyloid-beta precursor protein sequence variant V717F (human)
hAPP/var:V717F
Yes
organism-sequence


PR:000025573 amyloid-beta precursor protein sequence variant V717G (human)
hAPP/var:V717G
Yes
organism-sequence


PR:000025574 amyloid-beta precursor protein sequence variant V717I (human)
hAPP/var:V717I
Yes
organism-sequence


PR:000025575 amyloid-beta precursor protein sequence variant V717L (human)
hAPP/var:V717L
Yes
organism-sequence


PR:000025576 amyloid-beta precursor protein sequence variant L723P (human)
hAPP/var:L723P
Yes
organism-sequence


PR:000025590 amyloid-beta precursor protein sequence variant E665D (human)
hAPP/var:E665D

organism-sequence


PR:000025591 amyloid-beta precursor protein sequence variant A673T (human)
hAPP/var:A673T
Yes
organism-sequence


PR:000025592 amyloid-beta precursor protein sequence variant H677R (human)
hAPP/var:H677R

organism-sequence


PR:000025593 amyloid-beta precursor protein sequence variant A713V (human)
hAPP/var:A713V

organism-sequence


PR:000025594 amyloid-beta precursor protein sequence variant V715A (human)
hAPP/var:V715A
Yes
organism-sequence


PR:000025595 amyloid-beta precursor protein sequence variant I716F (human)
hAPP/var:I716F
Yes
organism-sequence


PR:000025596 amyloid-beta precursor protein sequence variant I716T (human)
hAPP/var:I716T
Yes
organism-sequence


PR:000025597 amyloid-beta precursor protein sequence variant T719P (human)
hAPP/var:T719P
Yes
organism-sequence


PR:000025598 amyloid-beta precursor protein sequence variant K724N (human)
hAPP/var:K724N
Yes
organism-sequence


PR:000025599 amyloid-beta precursor protein sequence variant E682K (human)
hAPP/var:E682K
Yes
organism-sequence


PR:000025600 amyloid-beta precursor protein sequence variant H733P (human)
hAPP/var:H733P

organism-sequence


PR:000025601 amyloid-beta precursor protein sequence variant KM670/671NL (human)
hAPP/var:KM670/671NL
Yes
organism-sequence


PR:000025602 amyloid-beta precursor protein sequence variant E693del (human)
hAPP/var:E693del
Yes
organism-sequence


PR:000028706 amyloid-beta precursor protein sequence variant E501K (human)
hAPP/var:E501K

organism-sequence


PR:000036990 amyloid-beta precursor protein sequence variant I716M (human)
hAPP/var:I716M
Yes
organism-sequence


PR:000036991 amyloid-beta precursor protein sequence variant M722K (human)
hAPP/var:M722K
Yes
organism-sequence


PR:000037518 amyloid-beta precursor protein sequence variant A673V (human)
hAPP/var:A673V
Yes
organism-sequence


PR:000037519 amyloid-beta precursor protein sequence variant D678H (human)
hAPP/var:D678H
Yes
organism-sequence


PR:000037520 amyloid-beta precursor protein sequence variant K687N (human)
hAPP/var:K687N
Yes
organism-sequence


PR:000045407 amyloid-beta precursor protein sequence variant A201V (human)
hAPP/var:A201V

organism-sequence


PR:000045408 amyloid-beta precursor protein sequence variant A235V (human)
hAPP/var:A235V

organism-sequence


PR:000045409 amyloid-beta precursor protein sequence variant D243N (human)
hAPP/var:D243N

organism-sequence


PR:000045410 amyloid-beta precursor protein sequence variant E246K (human)
hAPP/var:E246K

organism-sequence


PR:000045411 amyloid-beta precursor protein sequence variant E296K (human)
hAPP/var:E296K

organism-sequence


PR:000045412 amyloid-beta precursor protein sequence variant P299L (human)
hAPP/var:P299L

organism-sequence


PR:000045413 amyloid-beta precursor protein sequence variant R468H (human)
hAPP/var:R468H

organism-sequence


PR:000045414 amyloid-beta precursor protein sequence variant A479S (human)
hAPP/var:A479S

organism-sequence


PR:000045415 amyloid-beta precursor protein sequence variant K496Q (human)
hAPP/var:K496Q

organism-sequence


PR:000045416 amyloid-beta precursor protein sequence variant A500T (human)
hAPP/var:A500T

organism-sequence


PR:000045417 amyloid-beta precursor protein sequence variant Y538H (human)
hAPP/var:Y538H

organism-sequence


PR:000045418 amyloid-beta precursor protein sequence variant V562I (human)
hAPP/var:V562I

organism-sequence


PR:000045419 amyloid-beta precursor protein sequence variant E599K (human)
hAPP/var:E599K

organism-sequence


PR:000045420 amyloid-beta precursor protein sequence variant T600M (human)
hAPP/var:T600M

organism-sequence


PR:000045421 amyloid-beta precursor protein sequence variant P620L (human)
hAPP/var:P620L

organism-sequence


PR:000045422 amyloid-beta precursor protein sequence variant P620A (human)
hAPP/var:P620A

organism-sequence


PR:000045423 amyloid-beta precursor protein sequence variant T663M (human)
hAPP/var:T663M

organism-sequence


PR:000045424 amyloid-beta precursor protein sequence variant G709S (human)
hAPP/var:G709S

organism-sequence


PR:P05067-1 amyloid-beta precursor protein isoform APP770 (human)
hAPP/iso:APP770

organism-sequence


PR:P05067-10 amyloid-beta precursor protein isoform APP639 (human)
hAPP/iso:APP639

organism-sequence


PR:P05067-11 amyloid-beta precursor protein isoform h11 (human)
hAPP/iso:h11

organism-sequence


PR:P05067-2 amyloid-beta precursor protein isoform APP305 (human)
hAPP/iso:APP305

organism-sequence


PR:P05067-3 amyloid-beta precursor protein isoform L-APP677 (human)
hAPP/iso:L-APP677

organism-sequence


PR:P05067-4 amyloid-beta precursor protein isoform APP695 (human)
hAPP/iso:APP695

organism-modification


PR:000085805 amyloid-beta precursor protein isoform APP695, signal peptide removed form (human)
hAPP/iso:APP695/SigPep-

organism-sequence


PR:P05067-5 amyloid-beta precursor protein isoform L-APP696 (human)
hAPP/iso:L-APP696

organism-sequence


PR:P05067-6 amyloid-beta precursor protein isoform APP714 (human)
hAPP/iso:APP714

organism-sequence


PR:P05067-7 amyloid-beta precursor protein isoform L-APP733 (human)
hAPP/iso:L-APP733

organism-sequence


PR:P05067-8 amyloid-beta precursor protein isoform APP751 (human)
hAPP/iso:APP751

organism-sequence


PR:P05067-9 amyloid-beta precursor protein isoform L-APP752 (human)
hAPP/iso:L-APP752

organism-modification


PR:000046368 amyloid-beta precursor protein, signal peptide removed form (human)
hAPP/SigPep-

organism-modification


PR:000062305 amyloid-beta precursor protein, signal peptide removed phosphorylated form (human)
hAPP/SigPep-/PhosRes+

organism-modification


PR:000085805 amyloid-beta precursor protein isoform APP695, signal peptide removed form (human)
hAPP/iso:APP695/SigPep-

organism-modification


PR:000050063 beta-amyloid protein 42 (human)
hAbeta(1-42)

organism-modification


PR:000050064 beta-amyloid protein 40 (human)
hAbeta(1-40)

organism-modification


PR:000053414 amyloid-beta precursor protein O-glycosylated 1 (human)
hAPP/OGlyco:1

organism-modification


PR:000053415 amyloid-beta precursor protein O-glycosylated 2 (human)
hAPP/OGlyco:2

organism-modification


PR:000053416 amyloid-beta precursor protein O-glycosylated 3 (human)
hAPP/OGlyco:3

organism-modification


PR:000053417 amyloid-beta precursor protein O-glycosylated 4 (human)
hAPP/OGlyco:4

organism-modification


PR:000053418 amyloid-beta precursor protein O-glycosylated 5 (human)
hAPP/OGlyco:5

organism-modification


PR:000053419 amyloid-beta precursor protein O-glycosylated 6 (human)
hAPP/OGlyco:6

organism-modification


PR:000053420 amyloid-beta precursor protein O-glycosylated 7 (human)
hAPP/OGlyco:7

organism-modification


PR:000053421 amyloid-beta precursor protein O-glycosylated 8 (human)
hAPP/OGlyco:8

organism-modification


PR:000053422 amyloid-beta precursor protein O-glycosylated 9 (human)
hAPP/OGlyco:9

organism-modification


PR:000062305 amyloid-beta precursor protein, signal peptide removed phosphorylated form (human)
hAPP/SigPep-/PhosRes+

organism-modification


PR:000064882 amyloid-beta precursor protein deaminated 1 (human)
hAPP/Deam:1

organism-modification


PR:000065087 amyloid-beta precursor protein deaminated 2 (human)
hAPP/Deam:2

organism-modification


PR:000067537 amyloid-beta precursor protein cysteinylated 1 (human)
hAPP/Cyst:1

organism-modification


PR:000069811 amyloid-beta precursor protein methylated 1 (human)
hAPP/Me:1

organism-modification


PR:000070765 amyloid-beta precursor protein deaminated 3 (human)
hAPP/Deam:3

organism-modification


PR:000076984 amyloid-beta precursor protein deaminated 4 (human)
hAPP/Deam:4

organism-modification


PR:000084999 amyloid-beta precursor protein cysteinylated 2 (human)
hAPP/Cyst:2

organism-modification


PR:000085118 amyloid-beta precursor protein deaminated 5 (human)
hAPP/Deam:5

organism-modification


PR:000085380 amyloid-beta precursor protein cysteinylated 3 (human)
hAPP/Cyst:3

organism-gene


PR:P08592 amyloid-beta precursor protein (rat)
rAPP

organism-sequence


PR:P08592-1 amyloid-beta precursor protein isoform rAPP770 (rat)
rAPP/iso:rAPP770

organism-sequence


PR:P08592-2 amyloid-beta precursor protein isoform rAPP695 (rat)
rAPP/iso:rAPP695

organism-sequence


PR:P08592-3 amyloid-beta precursor protein isoform rL-APP677 (rat)
rAPP/iso:rL-APP677

organism-sequence


PR:P08592-4 amyloid-beta precursor protein isoform rL-APP696 (rat)
rAPP/iso:rL-APP696

organism-sequence


PR:P08592-5 amyloid-beta precursor protein isoform rAPP714 (rat)
rAPP/iso:rAPP714

organism-sequence


PR:P08592-6 amyloid-beta precursor protein isoform rL-APP733 (rat)
rAPP/iso:rL-APP733

organism-sequence


PR:P08592-7 amyloid-beta precursor protein isoform rAPP751 (rat)
rAPP/iso:rAPP751

organism-sequence


PR:P08592-8 amyloid-beta precursor protein isoform rL-APP752 (rat)
rAPP/iso:rL-APP752

organism-gene


PR:P12023 amyloid-beta precursor protein (mouse)
mAPP

organism-sequence


PR:000025559 amyloid-beta precursor protein sequence variant (mouse)
mAPP/var+

organism-sequence


PR:P12023-1 amyloid-beta precursor protein isoform APP770 (mouse)
mAPP/iso:APP770

organism-sequence


PR:P12023-2 amyloid-beta precursor protein isoform APP695 (mouse)
mAPP/iso:APP695

organism-sequence


PR:P12023-3 amyloid-beta precursor protein isoform APP751 (mouse)
mAPP/iso:APP751

organism-sequence


PR:P12023-4 amyloid-beta precursor protein isoform APP714 (mouse)
mAPP/iso:APP714

organism-modification


PR:000085741 beta-amyloid protein 40 (mouse)
mAbeta(1-40)

organism-gene


PR:P14599 amyloid-beta-like protein (fruit fly)
fly-APP

sequence


PR:000025522 amyloid-beta precursor protein isoform APP770
APP/iso:APP770

organism-sequence


PR:P05067-1 amyloid-beta precursor protein isoform APP770 (human)
hAPP/iso:APP770

organism-sequence


PR:P12023-1 amyloid-beta precursor protein isoform APP770 (mouse)
mAPP/iso:APP770

modification


PR:000025548 amyloid-beta precursor protein isoform APP770, signal peptide removed form
APP/iso:APP770/SigPep-

sequence


PR:000025523 amyloid-beta precursor protein isoform APP305
APP/iso:APP305

organism-sequence


PR:P05067-2 amyloid-beta precursor protein isoform APP305 (human)
hAPP/iso:APP305

modification


PR:000025549 amyloid-beta precursor protein isoform APP305, signal peptide removed form
APP/iso:APP305/SigPep-

sequence


PR:000025524 amyloid-beta precursor protein isoform L-APP677
APP/iso:L-APP677

organism-sequence


PR:P05067-3 amyloid-beta precursor protein isoform L-APP677 (human)
hAPP/iso:L-APP677

modification


PR:000025550 amyloid-beta precursor protein isoform L-APP677, signal peptide removed form
APP/iso:L-APP677/SigPep-

sequence


PR:000025525 amyloid-beta precursor protein isoform APP695
APP/iso:APP695

organism-sequence


PR:P05067-4 amyloid-beta precursor protein isoform APP695 (human)
hAPP/iso:APP695

organism-modification


PR:000085805 amyloid-beta precursor protein isoform APP695, signal peptide removed form (human)
hAPP/iso:APP695/SigPep-

organism-sequence


PR:P12023-2 amyloid-beta precursor protein isoform APP695 (mouse)
mAPP/iso:APP695

modification


PR:000025551 amyloid-beta precursor protein isoform APP695, signal peptide removed form
APP/iso:APP695/SigPep-

organism-modification


PR:000085805 amyloid-beta precursor protein isoform APP695, signal peptide removed form (human)
hAPP/iso:APP695/SigPep-

sequence


PR:000025526 amyloid-beta precursor protein isoform L-APP696
APP/iso:L-APP696

organism-sequence


PR:P05067-5 amyloid-beta precursor protein isoform L-APP696 (human)
hAPP/iso:L-APP696

modification


PR:000025552 amyloid-beta precursor protein isoform L-APP696, signal peptide removed form
APP/iso:L-APP696/SigPep-

sequence


PR:000025527 amyloid-beta precursor protein isoform APP714
APP/iso:APP714

organism-sequence


PR:P05067-6 amyloid-beta precursor protein isoform APP714 (human)
hAPP/iso:APP714

organism-sequence


PR:P12023-4 amyloid-beta precursor protein isoform APP714 (mouse)
mAPP/iso:APP714

modification


PR:000025553 amyloid-beta precursor protein isoform APP714, signal peptide removed form
APP/iso:APP714/SigPep-

sequence


PR:000025528 amyloid-beta precursor protein isoform L-APP733
APP/iso:L-APP733

organism-sequence


PR:P05067-7 amyloid-beta precursor protein isoform L-APP733 (human)
hAPP/iso:L-APP733

modification


PR:000025554 amyloid-beta precursor protein isoform L-APP733, signal peptide removed form
APP/iso:L-APP733/SigPep-

sequence


PR:000025529 amyloid-beta precursor protein isoform APP751
APP/iso:APP751

organism-sequence


PR:P05067-8 amyloid-beta precursor protein isoform APP751 (human)
hAPP/iso:APP751

organism-sequence


PR:P12023-3 amyloid-beta precursor protein isoform APP751 (mouse)
mAPP/iso:APP751

modification


PR:000025555 amyloid-beta precursor protein isoform APP751, signal peptide removed form
APP/iso:APP751/SigPep-

sequence


PR:000025530 amyloid-beta precursor protein isoform L-APP752
APP/iso:L-APP752

organism-sequence


PR:P05067-9 amyloid-beta precursor protein isoform L-APP752 (human)
hAPP/iso:L-APP752

modification


PR:000025556 amyloid-beta precursor protein isoform L-APP752, signal peptide removed form
APP/iso:L-APP752/SigPep-

sequence


PR:000025531 amyloid-beta precursor protein isoform APP639
APP/iso:APP639

organism-sequence


PR:P05067-10 amyloid-beta precursor protein isoform APP639 (human)
hAPP/iso:APP639

modification


PR:000025557 amyloid-beta precursor protein isoform APP639, signal peptide removed form
APP/iso:APP639/SigPep-

modification


PR:000019035 amyloid-beta precursor protein, signal peptide removed form
APP/SigPep-

modification


PR:000025548 amyloid-beta precursor protein isoform APP770, signal peptide removed form
APP/iso:APP770/SigPep-

modification


PR:000025549 amyloid-beta precursor protein isoform APP305, signal peptide removed form
APP/iso:APP305/SigPep-

modification


PR:000025550 amyloid-beta precursor protein isoform L-APP677, signal peptide removed form
APP/iso:L-APP677/SigPep-

modification


PR:000025551 amyloid-beta precursor protein isoform APP695, signal peptide removed form
APP/iso:APP695/SigPep-

organism-modification


PR:000085805 amyloid-beta precursor protein isoform APP695, signal peptide removed form (human)
hAPP/iso:APP695/SigPep-

modification


PR:000025552 amyloid-beta precursor protein isoform L-APP696, signal peptide removed form
APP/iso:L-APP696/SigPep-

modification


PR:000025553 amyloid-beta precursor protein isoform APP714, signal peptide removed form
APP/iso:APP714/SigPep-

modification


PR:000025554 amyloid-beta precursor protein isoform L-APP733, signal peptide removed form
APP/iso:L-APP733/SigPep-

modification


PR:000025555 amyloid-beta precursor protein isoform APP751, signal peptide removed form
APP/iso:APP751/SigPep-

modification


PR:000025556 amyloid-beta precursor protein isoform L-APP752, signal peptide removed form
APP/iso:L-APP752/SigPep-

modification


PR:000025557 amyloid-beta precursor protein isoform APP639, signal peptide removed form
APP/iso:APP639/SigPep-

modification


PR:000025577 soluble APP-alpha
S-APP-alpha

modification


PR:000025578 soluble APP-beta
S-APP-beta

modification


PR:000025579 soluble APP-theta
S-APP-theta

modification


PR:000025580 C99
APP-C99

modification


PR:000036193 amyloid beta peptide
Abeta

modification


PR:000025583 beta-amyloid protein 42
Abeta(1-42)

organism-modification


PR:000050063 beta-amyloid protein 42 (human)
hAbeta(1-42)

modification


PR:000025584 beta-amyloid protein 40
Abeta(1-40)

organism-modification


PR:000050064 beta-amyloid protein 40 (human)
hAbeta(1-40)

organism-modification


PR:000085741 beta-amyloid protein 40 (mouse)
mAbeta(1-40)

modification


PR:000025581 C83
APP-C83

modification


PR:000025587 P3(42)
APP-P3(42)

modification


PR:000025588 P3(40)
APP-P3(40)

modification


PR:000025582 C80
APP-C80

organism-modification


PR:000046368 amyloid-beta precursor protein, signal peptide removed form (human)
hAPP/SigPep-

organism-modification


PR:000062305 amyloid-beta precursor protein, signal peptide removed phosphorylated form (human)
hAPP/SigPep-/PhosRes+

organism-modification


PR:000085805 amyloid-beta precursor protein isoform APP695, signal peptide removed form (human)
hAPP/iso:APP695/SigPep-

modification


PR:000019036 amyloid-beta precursor protein proteolytic cleavage product
APP/ClvPrd

modification


PR:000025577 soluble APP-alpha
S-APP-alpha

modification


PR:000025578 soluble APP-beta
S-APP-beta

modification


PR:000025579 soluble APP-theta
S-APP-theta

modification


PR:000025580 C99
APP-C99

modification


PR:000036193 amyloid beta peptide
Abeta

modification


PR:000025583 beta-amyloid protein 42
Abeta(1-42)

organism-modification


PR:000050063 beta-amyloid protein 42 (human)
hAbeta(1-42)

modification


PR:000025584 beta-amyloid protein 40
Abeta(1-40)

organism-modification


PR:000050064 beta-amyloid protein 40 (human)
hAbeta(1-40)

organism-modification


PR:000085741 beta-amyloid protein 40 (mouse)
mAbeta(1-40)

modification


PR:000025581 C83
APP-C83

modification


PR:000025587 P3(42)
APP-P3(42)

modification


PR:000025588 P3(40)
APP-P3(40)

modification


PR:000025582 C80
APP-C80

modification


PR:000025585 gamma-secretase C-terminal fragment 57
APP-CTF(57)

modification


PR:000025586 gamma-secretase C-terminal fragment 59
APP-CTF(59)

modification


PR:000025587 P3(42)
APP-P3(42)

modification


PR:000025588 P3(40)
APP-P3(40)

modification


PR:000025589 gamma-secretase C-terminal fragment 50
APP-CTF(50)

modification


PR:000025744 precursor of amyloid-beta precursor protein gamma-secretase C-terminal fragment
APP-preCTF

modification


PR:000025580 C99
APP-C99

modification


PR:000036193 amyloid beta peptide
Abeta

modification


PR:000025583 beta-amyloid protein 42
Abeta(1-42)

organism-modification


PR:000050063 beta-amyloid protein 42 (human)
hAbeta(1-42)

modification


PR:000025584 beta-amyloid protein 40
Abeta(1-40)

organism-modification


PR:000050064 beta-amyloid protein 40 (human)
hAbeta(1-40)

organism-modification


PR:000085741 beta-amyloid protein 40 (mouse)
mAbeta(1-40)

modification


PR:000025581 C83
APP-C83

modification


PR:000025587 P3(42)
APP-P3(42)

modification


PR:000025588 P3(40)
APP-P3(40)

modification


PR:000025585 gamma-secretase C-terminal fragment 57
APP-CTF(57)

modification


PR:000025586 gamma-secretase C-terminal fragment 59
APP-CTF(59)

modification


PR:000025589 gamma-secretase C-terminal fragment 50
APP-CTF(50)

modification


PR:000036193 amyloid beta peptide
Abeta

modification


PR:000025583 beta-amyloid protein 42
Abeta(1-42)

organism-modification


PR:000050063 beta-amyloid protein 42 (human)
hAbeta(1-42)

modification


PR:000025584 beta-amyloid protein 40
Abeta(1-40)

organism-modification


PR:000050064 beta-amyloid protein 40 (human)
hAbeta(1-40)

organism-modification


PR:000085741 beta-amyloid protein 40 (mouse)
mAbeta(1-40)

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000025560 hAPP/var:D678N
Example: UniProtKB:P05067-1, Asp-678, CHEBI:50347		 associated_with_disease_progressionDO:10652 Alzheimer's disease PMID:15201367; UniProtKB_VAR:VAR_044424
PR:000025561 hAPP/var:A692G
Example: UniProtKB:P05067-1, Ala-692, CHEBI:29947		 associated_with_disease_progressionDO:10652 Alzheimer's disease PMID:11311152; PMID:1303239; PMID:9754958; UniProtKB_VAR:VAR_000016
PR:000025562 hAPP/var:E693G
Example: UniProtKB:P05067-1, Glu-693, CHEBI:29947		 associated_with_disease_progressionDO:10652 Alzheimer's disease PMID:11528419; PMID:1415269; UniProtKB_VAR:VAR_014215
PR:000025563 hAPP/var:E693K
Example: UniProtKB:P05067-1, Glu-693, CHEBI:29967		 associated_with_disease_progressionDO:9246 cerebral amyloid angiopathy UniProtKB_VAR:VAR_014216
PR:000025564 hAPP/var:E693Q
Example: UniProtKB:P05067-1, Glu-693, CHEBI:30011		 associated_with_disease_progressionDO:9246 cerebral amyloid angiopathy PMID:2111584; UniProtKB_VAR:VAR_000017
PR:000025565 hAPP/var:D694N
Example: UniProtKB:P05067-1, Asp-694, CHEBI:50347		 associated_with_disease_progressionDO:10652 Alzheimer's disease Alzforum:app-d694n-iowa
DO:9246 cerebral amyloid angiopathy PMID:11409420; PMID:12654973; UniProtKB_VAR:VAR_014217
PR:000025566 hAPP/var:L705V
Example: UniProtKB:P05067-1, Leu-705, CHEBI:30015		 associated_with_disease_progressionDO:9246 cerebral amyloid angiopathy PMID:16178030; UniProtKB_VAR:VAR_032276
PR:000025567 hAPP/var:A713T
Example: UniProtKB:P05067-1, Ala-713, CHEBI:30013		 associated_with_disease_progressionDO:10652 Alzheimer's disease PMID:1303275; PMID:15365148; UniProtKB_VAR:VAR_000019
DO:9246 cerebral amyloid angiopathy Alzforum:app-a713t
PR:000025568 hAPP/var:T714A
Example: UniProtKB:P05067-1, Thr-714, CHEBI:46217		 associated_with_disease_progressionDO:10652 Alzheimer's disease PMID:12034808; UniProtKB_VAR:VAR_032277
PR:000025569 hAPP/var:T714I
Example: UniProtKB:P05067-1, Thr-714, CHEBI:30009		 associated_with_disease_progressionDO:10652 Alzheimer's disease PMID:11063718; PMID:15668448; UniProtKB_VAR:VAR_014218
PR:000025570 hAPP/var:V715M
Example: UniProtKB:P05067-1, Val-715, CHEBI:16044		 associated_with_disease_progressionDO:10652 Alzheimer's disease PMID:10097173; UniProtKB_VAR:VAR_010108
PR:000025571 hAPP/var:I716V
Example: UniProtKB:P05067-1, Ile-716, CHEBI:30015		 associated_with_disease_progressionDO:10652 Alzheimer's disease PMID:9328472; UniProtKB_VAR:VAR_000020
PR:000025572 hAPP/var:V717F
Example: UniProtKB:P05067-1, Val-717, CHEBI:29997		 associated_with_disease_progressionDO:10652 Alzheimer's disease PMID:1925564; PMID:8267572; PMID:8290042; PMID:8476439; UniProtKB_VAR:VAR_000023
PR:000025573 hAPP/var:V717G
Example: UniProtKB:P05067-1, Val-717, CHEBI:29947		 associated_with_disease_progressionDO:10652 Alzheimer's disease PMID:1944558; PMID:8476439; UniProtKB_VAR:VAR_000022
PR:000025574 hAPP/var:V717I
Example: UniProtKB:P05067-1, Val-717, CHEBI:30009		 associated_with_disease_progressionDO:10652 Alzheimer's disease PMID:10631141; PMID:1671712; PMID:1678058; PMID:1908231; PMID:8267572; PMID:8476439; PMID:8577393; UniProtKB_VAR:VAR_000021
PR:000025575 hAPP/var:V717L
Example: UniProtKB:P05067-1, Val-717, CHEBI:30006		 associated_with_disease_progressionDO:10652 Alzheimer's disease PMID:10867787; UniProtKB_VAR:VAR_014219
PR:000025576 hAPP/var:L723P
Example: UniProtKB:P05067-1, Leu-723, CHEBI:50342		 associated_with_disease_progressionDO:10652 Alzheimer's disease PMID:10665499; UniProtKB_VAR:VAR_010109
PR:000025591 hAPP/var:A673T
Example: UniProtKB:P05067-1, Ala-673, CHEBI:30013		 located_inD10652 Alzheimer's disease Alzforum:app-a673t-icelandic
PR:000025594 hAPP/var:V715A
Example: UniProtKB:P05067-1, Val-715, CHEBI:46217		 associated_with_disease_progressionDO:10652 Alzheimer's disease Alzforum:app-v715a-german
PR:000025595 hAPP/var:I716F
Example: UniProtKB:P05067-1, Ile-716, CHEBI:29997		 associated_with_disease_progressionDO:10652 Alzheimer's disease Alzforum:app-i716f-iberian
PR:000025596 hAPP/var:I716T
Example: UniProtKB:P05067-1, Ile-716, CHEBI:30013		 associated_with_disease_progressionDO:10652 Alzheimer's disease Alzforum:app-i716t
PR:000025597 hAPP/var:T719P
Example: UniProtKB:P05067-1, Thr-719, CHEBI:50342		 associated_with_disease_progressionDO:10652 Alzheimer's disease Alzforum:app-t719p
PR:000025598 hAPP/var:K724N
Example: UniProtKB:P05067-1, Lys-724, CHEBI:50347		 associated_with_disease_progressionDO:10652 Alzheimer's disease Alzforum:app-k724n-belgian
PR:000025599 hAPP/var:E682K
Example: UniProtKB:P05067-1, Glu-682, CHEBI:29967		 associated_with_disease_progressionDO:10652 Alzheimer's disease Alzforum:app-e682k-leuven
PR:000025601 hAPP/var:KM670/671NL
Example: UniProtKB:P05067-1, Lys-670, CHEBI:50347|Met-671, CHEBI:30006		 associated_with_disease_progressionDO:10652 Alzheimer's disease UniProtKB_VAR:VAR_000015
PR:000025602 hAPP/var:E693del
Example: UniProtKB:P05067-1, 1-692, 694-770		 associated_with_disease_progressionDO:10652 Alzheimer's disease Alzforum:app-e693del-osaka
PR:000036990 hAPP/var:I716M
Example: UniProtKB:P05067-1, Ile-716, CHEBI:16044		 associated_with_disease_progressionDO:10652 Alzheimer's disease Alzforum:app-i716m
PR:000036991 hAPP/var:M722K
Example: UniProtKB:P05067-1, Met-722, CHEBI:29967		 associated_with_disease_progressionDO:10652 Alzheimer's disease Alzforum:app-m722k
PR:000037518 hAPP/var:A673V
Example: UniProtKB:P05067-1, Ala-673, CHEBI:30015		 associated_with_disease_progressionDO:10652 Alzheimer's disease Alzforum:app-a673v
PR:000037519 hAPP/var:D678H
Example: UniProtKB:P05067-1, Asp-678, CHEBI:29979		 associated_with_disease_progressionDO:10652 Alzheimer's disease Alzforum:app-d678h-taiwanese
PR:000037520 hAPP/var:K687N
Example: UniProtKB:P05067-1, Lys-687, CHEBI:50347		 associated_with_disease_progressionDO:10652 Alzheimer's disease Alzforum:app-k687n