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Protein Ontology report - amyloid-beta precursor protein
PR:000004168 - http://purl.obolibrary.org/obo/PR_000004168
 
  Protein Forms      
Ontology Information Show OBO stanza
  PRO ID
PR:000004168   
  PRO nameamyloid-beta precursor protein 
  Synonyms
PRO-Short-label: EXACT:APP
Gene-based: RELATED:A4 | AD1
Other: EXACT:ABPP | AG | alzheimer disease amyloid A4 protein homolog | alzheimer disease amyloid protein | amyloid beta A4 protein | amyloid precursor protein | amyloid-beta (A4) precursor protein | amyloid-beta A4 protein | amyloidogenic glycoprotein | APPI | cerebral vascular amyloid peptide | CVAP | PN-II | PreA4 | protease nexin-II
  Definition"A protein that is a translation product of the human APP gene or a 1:1 ortholog thereof." [PRO:DNx] 
  CommentRequested by=Alzforum. 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene0                                                  Organism-Gene 0                                        
         Sequence0                                                  Organism-Sequence 0                                        
         Modification0                                                  Organism-Modification 0                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Category  
PRO Form Name
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000004168 amyloid-beta precursor protein, APP





PR:000019035 amyloid-beta precursor protein, signal peptide removed form,





PR:000025548 amyloid-beta precursor protein isoform APP770, signal peptide removed form,





PR:000025549 amyloid-beta precursor protein isoform APP305, signal peptide removed form,





PR:000025550 amyloid-beta precursor protein isoform L-APP677, signal peptide removed form,





PR:000025551 amyloid-beta precursor protein isoform APP695, signal peptide removed form,





PR:000025552 amyloid-beta precursor protein isoform L-APP696, signal peptide removed form,





PR:000025553 amyloid-beta precursor protein isoform APP714, signal peptide removed form,





PR:000025554 amyloid-beta precursor protein isoform L-APP733, signal peptide removed form,





PR:000025555 amyloid-beta precursor protein isoform APP751, signal peptide removed form,





PR:000025556 amyloid-beta precursor protein isoform L-APP752, signal peptide removed form,





PR:000025557 amyloid-beta precursor protein isoform APP639, signal peptide removed form,





PR:000025577 soluble APP-alpha,





PR:000025578 soluble APP-beta,





PR:000025579 soluble APP-theta,





PR:000025580 C99,





PR:000036193 amyloid beta peptide,





PR:000025583 beta-amyloid protein 42,





PR:000050063 beta-amyloid protein 42 (human),





PR:000025584 beta-amyloid protein 40,





PR:000050064 beta-amyloid protein 40 (human),





PR:000025581 C83,





PR:000025587 P3(42),





PR:000025588 P3(40),





PR:000025582 C80,





PR:000046368 amyloid-beta precursor protein, signal peptide removed form (human),





PR:000019036 amyloid-beta precursor protein proteolytic cleavage product,





PR:000025577 soluble APP-alpha,





PR:000025578 soluble APP-beta,





PR:000025579 soluble APP-theta,





PR:000025580 C99,





PR:000036193 amyloid beta peptide,





PR:000025583 beta-amyloid protein 42,





PR:000050063 beta-amyloid protein 42 (human),





PR:000025584 beta-amyloid protein 40,





PR:000050064 beta-amyloid protein 40 (human),





PR:000025581 C83,





PR:000025587 P3(42),





PR:000025588 P3(40),





PR:000025582 C80,





PR:000025585 gamma-secretase C-terminal fragment 57,





PR:000025586 gamma-secretase C-terminal fragment 59,





PR:000025587 P3(42),





PR:000025588 P3(40),





PR:000025589 gamma-secretase C-terminal fragment 50,





PR:000025744 precursor of amyloid-beta precursor protein gamma-secretase C-terminal fragment,





PR:000025580 C99,





PR:000036193 amyloid beta peptide,





PR:000025583 beta-amyloid protein 42,





PR:000050063 beta-amyloid protein 42 (human),





PR:000025584 beta-amyloid protein 40,





PR:000050064 beta-amyloid protein 40 (human),





PR:000025581 C83,





PR:000025587 P3(42),





PR:000025588 P3(40),





PR:000025585 gamma-secretase C-terminal fragment 57,





PR:000025586 gamma-secretase C-terminal fragment 59,





PR:000025589 gamma-secretase C-terminal fragment 50,





PR:000036193 amyloid beta peptide,





PR:000025583 beta-amyloid protein 42,





PR:000050063 beta-amyloid protein 42 (human),





PR:000025584 beta-amyloid protein 40,





PR:000050064 beta-amyloid protein 40 (human),





PR:000025522 amyloid-beta precursor protein isoform APP770,





PR:000025548 amyloid-beta precursor protein isoform APP770, signal peptide removed form,

organism-sequence


PR:P05067-1 amyloid-beta precursor protein isoform APP770 (human), hAPP/iso:APP770





PR:P12023-1 amyloid-beta precursor protein isoform APP770 (mouse),





PR:000025523 amyloid-beta precursor protein isoform APP305,





PR:000025549 amyloid-beta precursor protein isoform APP305, signal peptide removed form,

organism-sequence


PR:P05067-2 amyloid-beta precursor protein isoform APP305 (human), hAPP/iso:APP305





PR:000025524 amyloid-beta precursor protein isoform L-APP677,





PR:000025550 amyloid-beta precursor protein isoform L-APP677, signal peptide removed form,

organism-sequence


PR:P05067-3 amyloid-beta precursor protein isoform L-APP677 (human), hAPP/iso:L-APP677





PR:000025525 amyloid-beta precursor protein isoform APP695,





PR:000025551 amyloid-beta precursor protein isoform APP695, signal peptide removed form,

organism-sequence


PR:P05067-4 amyloid-beta precursor protein isoform APP695 (human), hAPP/iso:APP695





PR:P12023-2 amyloid-beta precursor protein isoform APP695 (mouse),





PR:000025526 amyloid-beta precursor protein isoform L-APP696,





PR:000025552 amyloid-beta precursor protein isoform L-APP696, signal peptide removed form,

organism-sequence


PR:P05067-5 amyloid-beta precursor protein isoform L-APP696 (human), hAPP/iso:L-APP696





PR:000025527 amyloid-beta precursor protein isoform APP714,





PR:000025553 amyloid-beta precursor protein isoform APP714, signal peptide removed form,

organism-sequence


PR:P05067-6 amyloid-beta precursor protein isoform APP714 (human), hAPP/iso:APP714





PR:P12023-4 amyloid-beta precursor protein isoform APP714 (mouse),





PR:000025528 amyloid-beta precursor protein isoform L-APP733,





PR:000025554 amyloid-beta precursor protein isoform L-APP733, signal peptide removed form,

organism-sequence


PR:P05067-7 amyloid-beta precursor protein isoform L-APP733 (human), hAPP/iso:L-APP733





PR:000025529 amyloid-beta precursor protein isoform APP751,





PR:000025555 amyloid-beta precursor protein isoform APP751, signal peptide removed form,

organism-sequence


PR:P05067-8 amyloid-beta precursor protein isoform APP751 (human), hAPP/iso:APP751





PR:P12023-3 amyloid-beta precursor protein isoform APP751 (mouse),





PR:000025530 amyloid-beta precursor protein isoform L-APP752,





PR:000025556 amyloid-beta precursor protein isoform L-APP752, signal peptide removed form,

organism-sequence


PR:P05067-9 amyloid-beta precursor protein isoform L-APP752 (human), hAPP/iso:L-APP752





PR:000025531 amyloid-beta precursor protein isoform APP639,





PR:000025557 amyloid-beta precursor protein isoform APP639, signal peptide removed form,

organism-sequence


PR:P05067-10 amyloid-beta precursor protein isoform APP639 (human), hAPP/iso:APP639

organism-gene


PR:P05067 amyloid-beta precursor protein (human), hAPP

organism-sequence


PR:000025558 amyloid-beta precursor protein sequence variant (human), hAPP/var+





PR:000025560 amyloid-beta precursor protein sequence variant D678N (human),





PR:000025561 amyloid-beta precursor protein sequence variant A692G (human),





PR:000025562 amyloid-beta precursor protein sequence variant E693G (human),





PR:000025563 amyloid-beta precursor protein sequence variant E693K (human),





PR:000025564 amyloid-beta precursor protein sequence variant E693Q (human),





PR:000025565 amyloid-beta precursor protein sequence variant D694N (human),





PR:000025566 amyloid-beta precursor protein sequence variant L705V (human),





PR:000025567 amyloid-beta precursor protein sequence variant A713T (human),





PR:000025568 amyloid-beta precursor protein sequence variant T714A (human),





PR:000025569 amyloid-beta precursor protein sequence variant T714I (human),





PR:000025570 amyloid-beta precursor protein sequence variant V715M (human),





PR:000025571 amyloid-beta precursor protein sequence variant I716V (human),





PR:000025572 amyloid-beta precursor protein sequence variant V717F (human),





PR:000025573 amyloid-beta precursor protein sequence variant V717G (human),





PR:000025574 amyloid-beta precursor protein sequence variant V717I (human),





PR:000025575 amyloid-beta precursor protein sequence variant V717L (human),





PR:000025576 amyloid-beta precursor protein sequence variant L723P (human),





PR:000025590 amyloid-beta precursor protein sequence variant E665D (human),





PR:000025591 amyloid-beta precursor protein sequence variant A673T (human),





PR:000025592 amyloid-beta precursor protein sequence variant H677R (human),





PR:000025593 amyloid-beta precursor protein sequence variant A713V (human),





PR:000025594 amyloid-beta precursor protein sequence variant V715A (human),





PR:000025595 amyloid-beta precursor protein sequence variant I716F (human),





PR:000025596 amyloid-beta precursor protein sequence variant I716T (human),





PR:000025597 amyloid-beta precursor protein sequence variant T719P (human),





PR:000025598 amyloid-beta precursor protein sequence variant K724N (human),





PR:000025599 amyloid-beta precursor protein sequence variant E682K (human),





PR:000025600 amyloid-beta precursor protein sequence variant H733P (human),





PR:000025601 amyloid-beta precursor protein sequence variant KM670/671NL (human),





PR:000025602 amyloid-beta precursor protein sequence variant E693del (human),





PR:000028706 amyloid-beta precursor protein sequence variant E501K (human),





PR:000036990 amyloid-beta precursor protein sequence variant I716M (human),





PR:000036991 amyloid-beta precursor protein sequence variant M722K (human),





PR:000037518 amyloid-beta precursor protein sequence variant A673V (human),





PR:000037519 amyloid-beta precursor protein sequence variant D678H (human),





PR:000037520 amyloid-beta precursor protein sequence variant K687N (human),

organism-sequence


PR:000045407 amyloid-beta precursor protein sequence variant A201V (human), hAPP/var:A201V

organism-sequence


PR:000045408 amyloid-beta precursor protein sequence variant A235V (human), hAPP/var:A235V





PR:000045409 amyloid-beta precursor protein sequence variant D243N (human),





PR:000045410 amyloid-beta precursor protein sequence variant E246K (human),





PR:000045411 amyloid-beta precursor protein sequence variant E296K (human),





PR:000045412 amyloid-beta precursor protein sequence variant P299L (human),





PR:000045413 amyloid-beta precursor protein sequence variant R468H (human),

organism-sequence


PR:000045414 amyloid-beta precursor protein sequence variant A479S (human), hAPP/var:A479S





PR:000045415 amyloid-beta precursor protein sequence variant K496Q (human),

organism-sequence


PR:000045416 amyloid-beta precursor protein sequence variant A500T (human), hAPP/var:A500T





PR:000045417 amyloid-beta precursor protein sequence variant Y538H (human),





PR:000045418 amyloid-beta precursor protein sequence variant V562I (human),





PR:000045419 amyloid-beta precursor protein sequence variant E599K (human),





PR:000045420 amyloid-beta precursor protein sequence variant T600M (human),





PR:000045421 amyloid-beta precursor protein sequence variant P620L (human),





PR:000045422 amyloid-beta precursor protein sequence variant P620A (human),





PR:000045423 amyloid-beta precursor protein sequence variant T663M (human),





PR:000045424 amyloid-beta precursor protein sequence variant G709S (human),





PR:000046368 amyloid-beta precursor protein, signal peptide removed form (human),





PR:000050063 beta-amyloid protein 42 (human),





PR:000050064 beta-amyloid protein 40 (human),





PR:000062305 amyloid-beta precursor protein, signal peptide removed phosphorylated form (human),

organism-sequence


PR:P05067-1 amyloid-beta precursor protein isoform APP770 (human), hAPP/iso:APP770

organism-sequence


PR:P05067-10 amyloid-beta precursor protein isoform APP639 (human), hAPP/iso:APP639

organism-sequence


PR:P05067-11 amyloid-beta precursor protein isoform h11 (human), hAPP/iso:h11

organism-sequence


PR:P05067-2 amyloid-beta precursor protein isoform APP305 (human), hAPP/iso:APP305

organism-sequence


PR:P05067-3 amyloid-beta precursor protein isoform L-APP677 (human), hAPP/iso:L-APP677

organism-sequence


PR:P05067-4 amyloid-beta precursor protein isoform APP695 (human), hAPP/iso:APP695

organism-sequence


PR:P05067-5 amyloid-beta precursor protein isoform L-APP696 (human), hAPP/iso:L-APP696

organism-sequence


PR:P05067-6 amyloid-beta precursor protein isoform APP714 (human), hAPP/iso:APP714

organism-sequence


PR:P05067-7 amyloid-beta precursor protein isoform L-APP733 (human), hAPP/iso:L-APP733

organism-sequence


PR:P05067-8 amyloid-beta precursor protein isoform APP751 (human), hAPP/iso:APP751

organism-sequence


PR:P05067-9 amyloid-beta precursor protein isoform L-APP752 (human), hAPP/iso:L-APP752

organism-modification


PR:000053414 amyloid-beta precursor protein O-glycosylated 1 (human), hAPP/OGlyco:1

organism-modification


PR:000053415 amyloid-beta precursor protein O-glycosylated 2 (human), hAPP/OGlyco:2

organism-modification


PR:000053416 amyloid-beta precursor protein O-glycosylated 3 (human), hAPP/OGlyco:3

organism-modification


PR:000053417 amyloid-beta precursor protein O-glycosylated 4 (human), hAPP/OGlyco:4

organism-modification


PR:000053418 amyloid-beta precursor protein O-glycosylated 5 (human), hAPP/OGlyco:5

organism-modification


PR:000053419 amyloid-beta precursor protein O-glycosylated 6 (human), hAPP/OGlyco:6

organism-modification


PR:000053420 amyloid-beta precursor protein O-glycosylated 7 (human), hAPP/OGlyco:7

organism-modification


PR:000053421 amyloid-beta precursor protein O-glycosylated 8 (human), hAPP/OGlyco:8

organism-modification


PR:000053422 amyloid-beta precursor protein O-glycosylated 9 (human), hAPP/OGlyco:9

organism-modification


PR:000064882 amyloid-beta precursor protein deaminated 1 (human), hAPP/Deam:1

organism-modification


PR:000065087 amyloid-beta precursor protein deaminated 2 (human), hAPP/Deam:2

organism-modification


PR:000067537 amyloid-beta precursor protein cysteinylated 1 (human), hAPP/Cyst:1

organism-modification


PR:000069811 amyloid-beta precursor protein methylated 1 (human), hAPP/Me:1

organism-modification


PR:000070765 amyloid-beta precursor protein deaminated 3 (human), hAPP/Deam:3

organism-modification


PR:000076984 amyloid-beta precursor protein deaminated 4 (human), hAPP/Deam:4

organism-modification


PR:000084999 amyloid-beta precursor protein cysteinylated 2 (human), hAPP/Cyst:2

organism-modification


PR:000085118 amyloid-beta precursor protein deaminated 5 (human), hAPP/Deam:5

organism-modification


PR:000085380 amyloid-beta precursor protein cysteinylated 3 (human), hAPP/Cyst:3





PR:P08592 amyloid-beta precursor protein (rat),





PR:P08592-1 amyloid-beta precursor protein isoform rAPP770 (rat),





PR:P08592-2 amyloid-beta precursor protein isoform rAPP695 (rat),





PR:P08592-3 amyloid-beta precursor protein isoform rL-APP677 (rat),





PR:P08592-4 amyloid-beta precursor protein isoform rL-APP696 (rat),





PR:P08592-5 amyloid-beta precursor protein isoform rAPP714 (rat),





PR:P08592-6 amyloid-beta precursor protein isoform rL-APP733 (rat),





PR:P08592-7 amyloid-beta precursor protein isoform rAPP751 (rat),





PR:P08592-8 amyloid-beta precursor protein isoform rL-APP752 (rat),





PR:P12023 amyloid-beta precursor protein (mouse),





PR:000025559 amyloid-beta precursor protein sequence variant (mouse),





PR:P12023-1 amyloid-beta precursor protein isoform APP770 (mouse),





PR:P12023-2 amyloid-beta precursor protein isoform APP695 (mouse),





PR:P12023-3 amyloid-beta precursor protein isoform APP751 (mouse),





PR:P12023-4 amyloid-beta precursor protein isoform APP714 (mouse),





PR:P14599 amyloid-beta-like protein (fruit fly),