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Protein Ontology report - ticam1:ticam2:activated TLR4 complex
PR:000027205 -
http://purl.obolibrary.org/obo/PR_000027205
Protein Forms
Annotations
Ontology Information
Show OBO stanza
PRO ID
PR:000027205
PRO name
ticam1:ticam2:activated TLR4 complex
Synonyms
Other
:
RELATED:
TRIF:TRAM:activated TLR4
Definition
"A protein-containing complex that is composed of activated Toll-like receptor 4 (TLR4), Ticam2, and Ticam1." [
PMID:17457343
,
PMID:18222170
, TLR:AMM]
Comment
Requested by=TLR.
PRO Category
complex
Parent
G0032991
protein-containing complex
Terms by PRO Category
Organism-Independent
Organism-Specific
Category
Number of Terms
Category
Number of Terms
Complex
1
Organism-Complex
2
Term Hierarchy
Visualization
DAG:
OLS:
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Protein Forms
Switch to
Compact View
Category
PRO ID
Name
Short Name
Definition
Ann.
Has Annotation?
Comp.
In Complex?
complex
PR:000027205
ticam1:ticam2:activated TLR4 complex
hTICAM2/iso:1/InitMet-/Myr:1
"A protein-containing complex that is composed of activated Toll-like receptor 4 (TLR4), Ticam2, and Ticam1." [PMID:17457343, PMID:18222170, TLR:AMM]
organism-complex
PR:000027207
ticam1:ticam2:activated TLR4 complex (mouse)
hTICAM2/iso:1/InitMet-/Myr:1
"A ticam1:ticam2:activated TLR4 complex whose components are encoded in the genome of mouse." [PMID:14519765, PMID:18222170, TLR:AMM]
Yes
organism-complex
PR:000027208
ticam1:ticam2:activated TLR4 complex (human)
hTICAM2/iso:1/InitMet-/Myr:1
"A ticam1:ticam2:activated TLR4 complex whose components are encoded in the genome of human." [Reactome:R-HSA-166172]
Yes
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Functional Annotation (PRO-centric view)
Switch to
GO Centric View
PRO Term
GO Annotation
Evidence
PR:000027207
hTICAM2/iso:1/InitMet-/Myr:1
acts_upstream_of_or_within
GO:0002756
MyD88-independent toll-like receptor signaling pathway
PMID:18222170
GO:0034142
toll-like receptor 4 signaling pathway
PMID:18222170
located_in
GO:0010008
endosome membrane
PMID:18222170
PR:000027208
hTICAM2/iso:1/InitMet-/Myr:1
acts_upstream_of_or_within
GO:0002756
MyD88-independent toll-like receptor signaling pathway
Reactome:REACT_6809
GO:0034142
toll-like receptor 4 signaling pathway
Reactome:REACT_6809
located_in
GO:0010008
endosome membrane
Reactome:REACT_7861