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Protein Ontology report - ticam1:ticam2:activated TLR4 complex
PR:000027205 - http://purl.obolibrary.org/obo/PR_000027205
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000027205   
  PRO nameticam1:ticam2:activated TLR4 complex 
  Synonyms
Other: RELATED:TRIF:TRAM:activated TLR4
  Definition"A protein-containing complex that is composed of activated Toll-like receptor 4 (TLR4), Ticam2, and Ticam1." [PMID:17457343, PMID:18222170, TLR:AMM] 
  CommentRequested by=TLR. 
  PRO Categorycomplex 
  ParentG0032991 protein-containing complex
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Complex1                                                  Organism-Complex 2                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Ann. Has Annotation?

Comp. In Complex?
complex


PR:000027205 ticam1:ticam2:activated TLR4 complex, hTICAM2/iso:1/InitMet-/Myr:1

organism-complex


PR:000027207 ticam1:ticam2:activated TLR4 complex (mouse), hTICAM2/iso:1/InitMet-/Myr:1
Yes
organism-complex


PR:000027208 ticam1:ticam2:activated TLR4 complex (human), hTICAM2/iso:1/InitMet-/Myr:1
Yes
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000027207 hTICAM2/iso:1/InitMet-/Myr:1
TLR4MD2LPSditt | TRIF:TRAM:activated TLR4 (mouse)
"A ticam1:ticam2:activated TLR4 complex whose components are encoded in the genome of mouse." [PMID:14519765, PMID:18222170, TLR:AMM]		 acts_upstream_of_or_withinGO:0002756 MyD88-independent toll-like receptor signaling pathway PMID:18222170
GO:0034142 toll-like receptor 4 signaling pathway PMID:18222170
located_inGO:0010008 endosome membrane PMID:18222170
PR:000027208 hTICAM2/iso:1/InitMet-/Myr:1
TRIF:TRAM:activated TLR4 (human)
"A ticam1:ticam2:activated TLR4 complex whose components are encoded in the genome of human." [Reactome:R-HSA-166172]		 acts_upstream_of_or_withinGO:0002756 MyD88-independent toll-like receptor signaling pathway Reactome:REACT_6809
GO:0034142 toll-like receptor 4 signaling pathway Reactome:REACT_6809
located_inGO:0010008 endosome membrane Reactome:REACT_7861