|
PRO ID
 |
|
| PRO name | viral dsRNA:TLR3 complex |
| Synonyms | | PRO-Short-label: | EXACT: | (vir)dsRNA:TLR3 |
|
| Definition | "A macromolecular complex that is composed of viral double stranded RNA (dsRNA) and a homodimer of TLR3. Viral dsRNA triggers an antiviral pathway mediated by Toll-like receptor 3. TLR3 dimerization occurs upon ligand binding to positively charged residues on the ectodomain termini of TLR3 wich are responsible for the interaction with sugar-phosphate groups of dsRNA." [PMID:18420935, PMID:20861016, PRO:CNA, PRO:DAN, Reactome:R-HSA-167985] |
| Comment | Requested by=TLR. |
| PRO Category | complex |
| Parent | G0032991 protein-containing complex
|
| Terms by PRO Category |
| Organism-Independent |
Organism-Specific |
| Category |
Number of Terms |
Category |
Number of Terms | | Complex | 1 |
Organism-Complex |
3 | | | |
Term Hierarchy
Visualization |
|
