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RACE-PRO
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Documentation
Protein Ontology report - transforming growth factor beta-1 isoform 1 (human)
PR:P01137-1 -
http://purl.obolibrary.org/obo/PR_P01137-1
Protein Forms
Complex
Annotations
Ontology Information
Show OBO stanza
/
PAF
/
GPI
PRO ID
PR:P01137-1
PRO name
transforming growth factor beta-1 isoform 1 (human)
Synonyms
PRO-Short-label
:
EXACT:
hTGFB1/iso:1
Definition
"A TGF-beta 1 isoform 1 that is encoded in the genome of human." [PRO:CNA]
PRO Category
organism-sequence
Parent
PR:000000397
TGF-beta 1 isoform 1
PR:P01137
transforming growth factor beta-1 (human)
Taxon
NCBITaxon:9606
Homo sapiens
Terms by PRO Category
Organism-Independent
Organism-Specific
Category
Number of Terms
Category
Number of Terms
Sequence
0
Organism-Sequence
1
Modification
0
Organism-Modification
3
Term Hierarchy
Visualization
DAG:
OLS:
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Related Cross References
Db identifiers
UniProtKB:P01137-1
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Protein Forms
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Extended View
Category
PRO Form Name
Short Name
Ann.
Has Annotation?
Comp.
In Complex?
organism-sequence
PR:P01137-1
transforming growth factor beta-1 isoform 1 (human)
hTGFB1/iso:1
Yes
organism-modification
PR:000025927
TGF-beta 1 isoform 1 mature form (human)
hTGFB1/iso:1/mature
Yes
Yes
organism-modification
PR:000026335
TGF-beta 1 isoform 1 inactive form (human)
hTGFB1/iso:1/inactive
Yes
organism-modification
PR:000036526
TGF-beta 1 isoform 1 latency associated peptide (human)
hTGFB1/iso:1/LAP
Yes
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hTGFB1/iso:1
forms found in complexes
hTGFB1/iso:1
Component
Complexes
PR:000025927
hTGFB1/iso:1/mature
PR:000025926
dimeric TGF-beta 1 (human)
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Functional Annotation (GO-centric view)
Switch to
PRO Centric View
Biological Process GO Term
Protein Forms & Complexes
Evidence
GO:0007179
transforming growth factor beta receptor signaling pathway
PR:000025927
hTGFB1/iso:1/mature
PMID:8471846
PR:000026335
hTGFB1/iso:1/inactive
PMID:3162913
PR:P01137-1
hTGFB1/iso:1
PMID:1544940
GO:0043066
negative regulation of apoptotic process
PR:000025927
hTGFB1/iso:1/mature
PMID:9918798
PR:P01137-1
hTGFB1/iso:1
PMID:9918798
Molecular Function GO Term
Protein Forms & Complexes
Evidence
NOT
GO:0005160
transforming growth factor beta receptor binding
PR:000026335
hTGFB1/iso:1/inactive
PMID:2677679
;
PMID:3162913
GO:0042803
protein homodimerization activity
PR:000025927
hTGFB1/iso:1/mature
PMID:3162913
;
PMID:8471846
PR:000026335
hTGFB1/iso:1/inactive
PMID:3162913
PR:P01137-1
hTGFB1/iso:1
PMID:1544940
Cellular Location GO Term
Protein Forms & Complexes
Evidence
GO:0005796
Golgi lumen
PR:P01137-1
hTGFB1/iso:1
PMID:1544940
GO:0031012
extracellular matrix
PR:000025927
hTGFB1/iso:1/mature
PMID:8294500
PR:000026335
hTGFB1/iso:1/inactive
PMID:17015622
;
PMID:8294500
GO:0032991
protein-containing complex
PR:000026335
hTGFB1/iso:1/inactive
PMID:3162913
PR:000036526
hTGFB1/iso:1/LAP
PMID:17015622
;
PMID:3162913
