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Protein Ontology report - estrogen receptor (human)
PR:P03372 - http://purl.obolibrary.org/obo/PR_P03372
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza / GPI
  PRO ID
PR:P03372   
  PRO nameestrogen receptor (human) 
  Synonyms
PRO-Short-label: EXACT:hESR1
Gene-based: RELATED:ESR | ESR1 | NR3A1
Other: EXACT:ER (human) | ER-alpha (human) | estradiol receptor (human) | nuclear receptor subfamily 3 group A member 1 (human)
  Definition"An estrogen receptor that is encoded in the genome of human." [PRO:DNx, UniProtKB:P03372] 
  PRO Categoryorganism-gene 
  ParentPR:000007204 estrogen receptor
PR:000029067 Homo sapiens protein
  Gene TemplateHGNC:3467 ESR1 (human)
  TaxonNCBITaxon:9606 Homo sapiens
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene0                                                  Organism-Gene 1                                        
         Sequence0                                                  Organism-Sequence 4                                        
         Modification0                                                  Organism-Modification 17                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:P03372
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Short Name
Ann. Has Annotation?

Comp. In Complex?
organism-gene


PR:P03372 estrogen receptor (human)
hESR1

organism-sequence


PR:P03372-1 estrogen receptor isoform 1 (human)
hESR1/iso:1

organism-modification


PR:000027724 estrogen receptor isoform 1 phosphorylated 1 (human)
hESR1/iso:1/Phos:1
Yes
organism-modification


PR:000027726 estrogen receptor isoform 1 phosphorylated 2 (human)
hESR1/iso:1/Phos:2
Yes
organism-modification


PR:000027754 estrogen receptor isoform 1 phosphorylated 3 (human)
hESR1/iso:1/Phos:3

organism-modification


PR:000027756 estrogen receptor isoform 1 acetylated 1 (human)
hESR1/iso:1/Ac:1
Yes
organism-modification


PR:000027776 estrogen receptor isoform 1 phosphorylated 4 (human)
hESR1/iso:1/Phos:4
Yes
organism-modification


PR:000027778 estrogen receptor isoform 1 phosphorylated 5 (human)
hESR1/iso:1/Phos:5

organism-sequence


PR:P03372-2 estrogen receptor isoform h2 (human)
hESR1/iso:h2

organism-sequence


PR:P03372-3 estrogen receptor isoform h3 (human)
hESR1/iso:h3

organism-modification


PR:000061250 estrogen receptor isoform h3 palmitoylated 1 (human)
hESR1/iso:h3/Palm:1

organism-modification


PR:000062654 estrogen receptor isoform h3 omega-methylated and palmitoylated 1 (human)
hESR1/iso:h3/Me1oPalm:1

organism-sequence


PR:P03372-4 estrogen receptor isoform h4 (human)
hESR1/iso:h4

organism-modification


PR:000063016 estrogen receptor isoform h4 omega-methylated and palmitoylated 1 (human)
hESR1/iso:h4/Me1oPalm:1

organism-modification


PR:000064345 estrogen receptor isoform h4 palmitoylated 1 (human)
hESR1/iso:h4/Palm:1

organism-modification


PR:000045630 estrogen receptor phosphorylated 1 (human)
hESR1/Phos:1

organism-modification


PR:000060689 estrogen receptor omega-methylated 1 (human)
hESR1/Me1o:1

organism-modification


PR:000061153 estrogen receptor phosphorylated 2 (human)
hESR1/Phos:2

organism-modification


PR:000061694 estrogen receptor palmitoylated 1 (human)
hESR1/Palm:1

organism-modification


PR:000063648 estrogen receptor omega-methylated and palmitoylated 1 (human)
hESR1/Me1oPalm:1

organism-modification


PR:000064707 estrogen receptor sumoylated 1 (human)
hESR1/Sumo:1

organism-modification


PR:000085884 estrogen receptor phosphorylated 3 (human)
hESR1/Phos:3

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000027724 hESR1/iso:1/Phos:1
UniProtKB:P03372-1, Ser-167, MOD:00046		 acts_upstream_of_or_withinGO:0045893 positive regulation of DNA-templated transcription PMID:19940156
PR:000027726 hESR1/iso:1/Phos:2
UniProtKB:P03372-1, Tyr-52/Tyr-219, MOD:00048		 acts_upstream_of_or_withinGO:0010628 positive regulation of gene expression PMID:20101225
enablesGO:0042803 protein homodimerization activity PMID:20101225
located_inGO:0005634 nucleus PMID:20101225
PR:000027756 hESR1/iso:1/Ac:1
UniProtKB:P03372-1, Lys-266/Lys-268, MOD:00064		 enablesGO:0003677 DNA binding PMID:16497729
PR:000027776 hESR1/iso:1/Phos:4
UniProtKB:P03372-1, Thr-311, MOD:00047		 acts_upstream_of_or_withinGO:0010628 positive regulation of gene expression PMID:12138194
located_inGO:0005634 nucleus PMID:12138194