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RACE-PRO
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Documentation
Protein Ontology report - estrogen receptor (human)
PR:P03372 -
http://purl.obolibrary.org/obo/PR_P03372
Protein Forms
Annotations
Ontology Information
Show OBO stanza
/
GPI
PRO ID
PR:P03372
PRO name
estrogen receptor (human)
Synonyms
PRO-Short-label
:
EXACT:
hESR1
Gene-based
:
RELATED:
ESR | ESR1 | NR3A1
Other
:
EXACT:
ER (human) | ER-alpha (human) | estradiol receptor (human) | nuclear receptor subfamily 3 group A member 1 (human)
Definition
"An estrogen receptor that is encoded in the genome of human." [PRO:DNx,
UniProtKB:P03372
]
PRO Category
organism-gene
Parent
PR:000007204
estrogen receptor
PR:000029067
Homo sapiens protein
Gene Template
HGNC:3467
ESR1 (human)
Taxon
NCBITaxon:9606
Homo sapiens
Terms by PRO Category
Organism-Independent
Organism-Specific
Category
Number of Terms
Category
Number of Terms
Gene
0
Organism-Gene
1
Sequence
0
Organism-Sequence
4
Modification
0
Organism-Modification
16
Term Hierarchy
Visualization
DAG:
OLS:
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Related Cross References
Db identifiers
UniProtKB:P03372
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Protein Forms
Switch to
Extended View
Category
PRO Form Name
Ann.
Has Annotation?
Comp.
In Complex?
organism-gene
PR:P03372
estrogen receptor (human), hESR1
organism-sequence
PR:P03372-1
estrogen receptor isoform 1 (human), hESR1/iso:1
organism-modification
PR:000027724
estrogen receptor isoform 1 phosphorylated 1 (human), hESR1/iso:1/Phos:1
Yes
organism-modification
PR:000027726
estrogen receptor isoform 1 phosphorylated 2 (human), hESR1/iso:1/Phos:2
Yes
organism-modification
PR:000027754
estrogen receptor isoform 1 phosphorylated 3 (human), hESR1/iso:1/Phos:3
organism-modification
PR:000027756
estrogen receptor isoform 1 acetylated 1 (human), hESR1/iso:1/Ac:1
Yes
organism-modification
PR:000027776
estrogen receptor isoform 1 phosphorylated 4 (human), hESR1/iso:1/Phos:4
Yes
organism-modification
PR:000027778
estrogen receptor isoform 1 phosphorylated 5 (human), hESR1/iso:1/Phos:5
organism-sequence
PR:P03372-2
estrogen receptor isoform h2 (human), hESR1/iso:h2
organism-sequence
PR:P03372-3
estrogen receptor isoform h3 (human), hESR1/iso:h3
organism-modification
PR:000061250
estrogen receptor isoform h3 palmitoylated 1 (human), hESR1/iso:h3/Palm:1
organism-modification
PR:000062654
estrogen receptor isoform h3 omega-methylated and palmitoylated 1 (human), hESR1/iso:h3/Me1oPalm:1
organism-sequence
PR:P03372-4
estrogen receptor isoform h4 (human), hESR1/iso:h4
organism-modification
PR:000063016
estrogen receptor isoform h4 omega-methylated and palmitoylated 1 (human), hESR1/iso:h4/Me1oPalm:1
organism-modification
PR:000064345
estrogen receptor isoform h4 palmitoylated 1 (human), hESR1/iso:h4/Palm:1
organism-modification
PR:000045630
estrogen receptor phosphorylated 1 (human), hESR1/Phos:1
organism-modification
PR:000060689
estrogen receptor omega-methylated 1 (human), hESR1/Me1o:1
organism-modification
PR:000061153
estrogen receptor phosphorylated 2 (human), hESR1/Phos:2
organism-modification
PR:000061694
estrogen receptor palmitoylated 1 (human), hESR1/Palm:1
organism-modification
PR:000063648
estrogen receptor omega-methylated and palmitoylated 1 (human), hESR1/Me1oPalm:1
organism-modification
PR:000064707
estrogen receptor sumoylated 1 (human), hESR1/Sumo:1
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Functional Annotation (PRO-centric view)
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GO Centric View
PRO Term
GO Annotation
Evidence
PR:000027724
hESR1/iso:1/Phos:1
UniProtKB:P03372-1, Ser-167, MOD:00046 | phospho-ERalpha-Ser-167
"An estrogen receptor isoform 1 phosphorylated 1 in human. UniProtKB:P03372-1, Ser-167, MOD:00046." [PMID:19940156, PRO:PD]
acts_upstream_of_or_within
GO:0045893
positive regulation of DNA-templated transcription
PMID:19940156
PR:000027726
hESR1/iso:1/Phos:2
UniProtKB:P03372-1, Tyr-52/Tyr-219, MOD:00048
"An estrogen receptor isoform 1 phosphorylated 2 in human. UniProtKB:P03372-1, Tyr-52/Tyr-219, MOD:00048." [PMID:20101225, PRO:PD]
acts_upstream_of_or_within
GO:0010628
positive regulation of gene expression
PMID:20101225
enables
GO:0042803
protein homodimerization activity
PMID:20101225
located_in
GO:0005634
nucleus
PMID:20101225
PR:000027756
hESR1/iso:1/Ac:1
UniProtKB:P03372-1, Lys-266/Lys-268, MOD:00064 | AcK266/268-ERalpha (human) | ERalpha acetylated (human)
"An estrogen receptor isoform 1 acetylated 1 in human. UniProtKB:P03372-1, Lys-266/Lys-268, MOD:00064." [PMID:16497729, PRO:PD]
enables
GO:0003677
DNA binding
PMID:16497729
PR:000027776
hESR1/iso:1/Phos:4
UniProtKB:P03372-1, Thr-311, MOD:00047 | pERalpha-Thr311
"An estrogen receptor isoform 1 phosphorylated 4 in human. UniProtKB:P03372-1, Thr-311, MOD:00047." [PMID:12138194, PRO:PD]
acts_upstream_of_or_within
GO:0010628
positive regulation of gene expression
PMID:12138194
located_in
GO:0005634
nucleus
PMID:12138194