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Protein Ontology report - myeloid differentiation primary response protein MyD88 (mouse)
PR:P22366 - http://purl.obolibrary.org/obo/PR_P22366
 
  Protein Forms  Complex  Annotations      
Ontology Information Show OBO stanza / PAF / GPI
  PRO ID
PR:P22366   
  PRO namemyeloid differentiation primary response protein MyD88 (mouse) 
  Synonyms
PRO-Short-label: EXACT:mMYD88
Gene-based: RELATED:Myd88
  Definition"A myeloid differentiation primary response protein MyD88 that is encoded in the genome of mouse." [OMA:P22366, PRO:CNA] 
  PRO Categoryorganism-gene 
  ParentPR:000001740 myeloid differentiation primary response protein MyD88
PR:000029032 Mus musculus protein
  Gene TemplateMGI:108005 Myd88 (mouse)
  TaxonNCBITaxon:10090 Mus musculus
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene0                                                  Organism-Gene 1                                        
         Sequence0                                                  Organism-Sequence 2                                        
         Modification0                                                  Organism-Modification 0                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:P22366
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Protein Forms Switch to Compact View   

Category  
PRO ID
Name
Short Name
Definition
Ann. Has Annotation?

Comp. In Complex?
organism-gene


PR:P22366
myeloid differentiation primary response protein MyD88 (mouse)
mMYD88
"A myeloid differentiation primary response protein MyD88 that is encoded in the genome of mouse." [OMA:P22366, PRO:CNA]

organism-sequence


PR:P22366-1
myeloid differentiation primary response protein MyD88 isoform 1 (mouse)
mMYD88/iso:1
"A myeloid differentiation primary response protein MyD88 isoform 1 that is encoded in the genome of mouse." [PMID:11909531, PRO:CNA]

Yes
organism-sequence


PR:P22366-2
myeloid differentiation primary response protein MyD88 isoform 2 (mouse)
mMYD88/iso:2
"A myeloid differentiation primary response protein MyD88 isoform 2 that is encoded in the genome of mouse." [PMID:11909531, PRO:CNA]
Yes
Yes
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mMYD88 forms found in complexes   

mMYD88 Component
 Complexes
PR:P22366ZDASHZ1 mMYD88/iso:1 PR:000027175 MYD88l:TIRAP:activated TLR4 receptor (mouse)
PR:000027187 IRAK4:MYD88:TIRAP:activated TLR4 complex (mouse)
PR:000027220 IRAK1:IRAK4:MYD88:TIRAP:activated TLR4 (mouse)
PR:000027221 pIRAK1:IRAK4:MYD88:TIRAP:activated TLR4 (mouse)
PR:000027267 IRAK3:IRAK1:IRAK4:MYD88:TIRAP:activated TLR4 (mouse)
PR:000037481 MYD88:TIRAP:PIP2:BTK:activated TLR4 complex (mouse)
PR:P22366ZDASHZ2 mMYD88/iso:2 PR:000027174 MYD88s:TIRAP:activated TLR4 receptor (mouse)
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:P22366-2 mMYD88/iso:2 acts_upstream_of_or_withinGO:0034125 negative regulation of MyD88-dependent toll-like receptor signaling pathway PMID:12538665