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Protein Ontology report - TNF receptor-associated factor 2 (human)
PR:Q12933 - http://purl.obolibrary.org/obo/PR_Q12933
 
  Protein Forms  Complex      
Ontology Information Show OBO stanza / GPI
  PRO ID
PR:Q12933   
  PRO nameTNF receptor-associated factor 2 (human) 
  Synonyms
PRO-Short-label: EXACT:hTRAF2
Gene-based: RELATED:TRAF2 | TRAP3
Other: EXACT:E3 ubiquitin-protein ligase TRAF2 (human) | RING-type E3 ubiquitin transferase TRAF2 (human) | tumor necrosis factor type 2 receptor-associated protein 3 (human)
  Definition"A TNF receptor-associated factor 2 that is encoded in the genome of human." [PRO:WCB, UniProtKB:Q12933
  PRO Categoryorganism-gene 
  ParentPR:000002288 TNF receptor-associated factor 2
PR:000029067 Homo sapiens protein
  Gene TemplateHGNC:12032 TRAF2 (human)
  TaxonNCBITaxon:9606 Homo sapiens
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene0                                                  Organism-Gene 1                                        
         Sequence0                                                  Organism-Sequence 4                                        
         Modification0                                                  Organism-Modification 5                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:Q12933
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Protein Forms Switch to Compact View   

Category  

PRO ID

Name

Short Name

Definition

Ann. Has Annotation?

Comp. In Complex?
organism-gene



PR:Q12933

TNF receptor-associated factor 2 (human)

hTRAF2


"A TNF receptor-associated factor 2 that is encoded in the genome of human." [PRO:WCB, UniProtKB:Q12933]


organism-sequence



PR:Q12933-1

TNF receptor-associated factor 2 isoform 1 (human)

hTRAF2/iso:1


"A TNF receptor-associated factor 2 isoform 1 that is encoded in the genome of human." [PRO:JAN]


organism-sequence



PR:Q12933-2

TNF receptor-associated factor 2 isoform 2 (human)

hTRAF2/iso:2


"A TNF receptor-associated factor 2 isoform 3 that is encoded in the genome of human." [PRO:JAN]


organism-sequence



PR:Q12933-3

TNF receptor-associated factor 2 isoform h3 (human)

hTRAF2/iso:h3


"A TNF receptor-associated factor 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q12933-3." [PRO:DNx, UniProtKB:Q12933]


organism-sequence



PR:Q12933-4

TNF receptor-associated factor 2 isoform h4 (human)

hTRAF2/iso:h4


"A TNF receptor-associated factor 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q12933-4." [PRO:DNx, UniProtKB:Q12933]


organism-modification



PR:000028382

TNF receptor-associated factor 2, initiator methionine removed form (human)

hTRAF2/InitMet-


"A TNF receptor-associated factor 2, initiator methionine removed form in human. Example: UniProtKB:Q12933-1, 2-501." [PRO:DNx]


Yes
organism-modification



PR:000049534

TNF receptor-associated factor 2, initiator methionine removed ubiquitinated form (human)

hTRAF2/InitMet-/UbiqLys+


"A TNF receptor-associated factor 2, initiator methionine removed form (human) that includes at least one ubiquitinated lysine. UniProtKB:Q12933, 2-501, MOD:01148." [PRO:DNx, Reactome:R-HSA-8862194]


organism-modification



PR:000045896

TNF receptor-associated factor 2 phosphorylated 1 (human)

hTRAF2/Phos:1


"A TNF receptor-associated factor 2 (human) that has been phosphorylated on the residue at the position equivalent to Ser-55 of the amino acid sequence represented by UniProtKB:Q12933-1. Example: UniProtKB:Q12933-1, Ser-55, MOD:00046." [iPTMnet:Q12933, PMID:19336568]


organism-modification



PR:000069067

TNF receptor-associated factor 2 cysteinylated 1 (human)

hTRAF2/Cyst:1


"A TNF receptor-associated factor 2 (human) that has been cysteinylated on the residue at the position equivalent to Cys-34 of the amino acid sequence represented by UniProtKB:Q12933-1. Example: UniProtKB:Q12933-1, Cys-34, MOD:00765." [IEDB_epitope:1577094, PRO:DNx]


organism-modification



PR:000079608

TNF receptor-associated factor 2 methylated 1 (human)

hTRAF2/Me:1


"A TNF receptor-associated factor 2 (human) that has been methylated on the residue at the position equivalent to Cys-182 of the amino acid sequence represented by UniProtKB:Q12933-1. Example: UniProtKB:Q12933-1, Cys-182, MOD:00660." [IEDB_epitope:999579, PRO:DNx]


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hTRAF2 forms found in complexes   

hTRAF2 Component
Complexes
PR:000028382 hTRAF2/InitMet- PR:000028432 TNF-alpha:TNF-R1:TRAPP:RIP1:TRAF2 complex (human)
PR:000028434 TRAF2:TRADD:RIP1 complex (human)
PR:000028435 TRADD:TRAF2:RIP1:FADD:caspase-8 complex (human)
PR:000028437 TRAF2:TRADD:RIP1:FADD (human)