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RACE-PRO
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Protein Ontology report - smad2 isoform Short
PR:000000469 -
http://purl.obolibrary.org/obo/PR_000000469
Protein Forms
Complex
Annotations
Ontology Information
Show OBO stanza
PRO ID
PR:000000469
PRO name
smad2 isoform Short
Synonyms
PRO-Short-label
:
EXACT:
SMAD2/iso:Short
Other
:
EXACT:
mothers against decapentaplegic homolog 2 isoform 2 | smad2 isoform 2
RELATED:
exon3delta | short isoform
Definition
"A smad2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by
UniProtKB:Q15796-2
or a 1:1 ortholog thereof." [
PMID:8752209
, PRO:CNA, PRO:DAN]
PRO Category
sequence
Parent
PR:000000364
smad2
Terms by PRO Category
Organism-Independent
Organism-Specific
Category
Number of Terms
Category
Number of Terms
Sequence
1
Organism-Sequence
2
Modification
5
Organism-Modification
4
Term Hierarchy
Visualization
DAG:
OLS:
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Protein Forms
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Extended View
Category
PRO Form Name
Ann.
Has Annotation?
Comp.
In Complex?
sequence
PR:000000469
smad2 isoform Short, SMAD2/iso:Short
organism-sequence
PR:Q15796-2
mothers against decapentaplegic homolog 2 isoform Short (human), hSMAD2/iso:Short
organism-modification
PR:000025938
smad2 isoform Short phosphorylated 1 (human), hSMAD2/iso:Short/Phos:1
Yes
Yes
organism-modification
PR:000036556
smad2 isoform Short acetylated and phosphorylated 1 (human), hSMAD2/iso:Short/AcPhos:1
Yes
organism-modification
PR:000045494
smad2 isoform Short unphosphorylated 1 (human), hSMAD2/iso:Short/UnPhos:1
organism-sequence
PR:Q62432-2
mothers against decapentaplegic homolog 2 isoform Short (mouse), mSMAD2/iso:Short
organism-modification
PR:000025943
smad2 isoform Short phosphorylated 1 (mouse), mSMAD2/iso:Short/Phos:1
Yes
Yes
modification
PR:000000575
smad2 isoform Short acetylated and phosphorylated form, SMAD2/iso:Short/AcPhos+
modification
PR:000000655
smad2 isoform Short acetylated and phosphorylated 1, SMAD2/iso:Short/AcPhos:1
organism-modification
PR:000036556
smad2 isoform Short acetylated and phosphorylated 1 (human), hSMAD2/iso:Short/AcPhos:1
Yes
modification
PR:000000576
smad2 isoform Short phosphorylated form, SMAD2/iso:Short/PhosRes+
modification
PR:000000575
smad2 isoform Short acetylated and phosphorylated form, SMAD2/iso:Short/AcPhos+
modification
PR:000000655
smad2 isoform Short acetylated and phosphorylated 1, SMAD2/iso:Short/AcPhos:1
organism-modification
PR:000036556
smad2 isoform Short acetylated and phosphorylated 1 (human), hSMAD2/iso:Short/AcPhos:1
Yes
modification
PR:000000656
smad2 isoform Short phosphorylated 1, SMAD2/iso:Short/Phos:1
Yes
organism-modification
PR:000025938
smad2 isoform Short phosphorylated 1 (human), hSMAD2/iso:Short/Phos:1
Yes
Yes
organism-modification
PR:000025943
smad2 isoform Short phosphorylated 1 (mouse), mSMAD2/iso:Short/Phos:1
Yes
Yes
modification
PR:000002571
smad2 isoform Short unmodified form, SMAD2/iso:Short/UnMod
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SMAD2/iso:Short
forms found in complexes
SMAD2/iso:Short
Component
Complexes
PR:000000656
SMAD2/iso:Short/Phos:1
PR:000025968
smad2-smad4 protein complex 2
PR:000025938
hSMAD2/iso:Short/Phos:1
PR:000025940
smad2-smad4 protein complex 2 (human)
PR:000025943
mSMAD2/iso:Short/Phos:1
PR:000025945
smad2-smad4 protein complex 2 (mouse)
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Functional Annotation (PRO-centric view)
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GO Centric View
PRO Term
GO Annotation
Evidence
PR:000025938
hSMAD2/iso:Short/Phos:1
UniProtKB:Q15796-2, Ser-435/Ser-437, MOD:00046
"A smad2 isoform Short phosphorylated 1 in human. This form is phosphorylated in the two last Ser of the C-terminal SSxS motif. UniProtKB:Q15796-2, Ser-435/Ser-437, MOD:00046." [PRO:CNA]
acts_upstream_of_or_within
GO:0007179
transforming growth factor beta receptor signaling pathway
PMID:9873005
enables
GO:0003677
DNA binding
PMID:14701940
;
PMID:9873005
GO:0003700
DNA-binding transcription factor activity
PMID:9873005
GO:0003712
transcription coregulator activity
PMID:14701940
;
PMID:9873005
PR:000025943
mSMAD2/iso:Short/Phos:1
UniProtKB:Q62432-2, Ser-435/Ser-437, MOD:00046
"A smad2 isoform Short phosphorylated 1 in mouse. This form is phosphorylated in the two last Ser of the C-terminal SSxS motif. UniProtKB:Q62432-2, Ser-435/Ser-437, MOD:00046." [PRO:CNA]
acts_upstream_of_or_within
GO:0007179
transforming growth factor beta receptor signaling pathway
PMID:15630024
enables
GO:0003700
DNA-binding transcription factor activity
PMID:15630024
PR:000036556
hSMAD2/iso:Short/AcPhos:1
UniProtKB:Q15796-2, Lys-19, MOD:00064|Ser-435/Ser-437, MOD:00046
"A smad2 isoform Short acetylated and phosphorylated 1 in human. UniProtKB:Q15796-2, Lys-19, MOD:00064|Ser-435/Ser-437, MOD:00046." [PMID:17074756, PRO:CNA]
acts_upstream_of_or_within
GO:0007179
transforming growth factor beta receptor signaling pathway
PMID:17074756
enables
GO:0003677
DNA binding
PMID:17074756
increased
GO:0003700
DNA-binding transcription factor activity
relative to
PR:000000656
SMAD2/iso:Short/Phos:1
PMID:17074756