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Protein Ontology report - nuclear factor NF-kappa-B p105 subunit
PR:000001754 - http://purl.obolibrary.org/obo/PR_000001754
 
  Protein Forms  Complex  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000001754   
  PRO namenuclear factor NF-kappa-B p105 subunit 
  Synonyms
PRO-Short-label: EXACT:NFKB1
Other: EXACT:DNA-binding factor KBF1 | EBP-1 | NF-kappa-B1 p84/NF-kappa-B1 p98 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
  Definition"A transcription factor NF-kappa-B subunit that is a translation product of the human NFKB1 gene or a 1:1 ortholog thereof. NF-kappa-B is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processed such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis." [PMID:15485931, PRO:JAN] 
  PRO Categorygene 
  ParentPR:000001753 transcription factor NF-kappa-B subunit
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 5                                        
         Sequence3                                                  Organism-Sequence 15                                        
         Modification5                                                  Organism-Modification 9                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000001754 nuclear factor NF-kappa-B p105 subunit, NFKB1

organism-gene


PR:P19838 nuclear factor NF-kappa-B p105 subunit (human), hNFKB1

Yes
organism-sequence


PR:P19838-1 nuclear factor NF-kappa-B p105 subunit isoform 1 (human), hNFKB1/iso:1

organism-sequence


PR:P19838-2 nuclear factor NF-kappa-B p105 subunit isoform 2 (human), hNFKB1/iso:2

organism-sequence


PR:P19838-3 nuclear factor NF-kappa-B p105 subunit isoform h3 (human), hNFKB1/iso:h3

organism-modification


PR:000035834 nuclear factor NF-kappa-B p50 subunit (human), hNFKBp50
Yes
Yes
organism-modification


PR:000045706 nuclear factor NF-kappa-B p105 subunit phosphorylated 1 (human), hNFKB1/Phos:1

organism-modification


PR:000048595 nuclear factor NF-kappa-B p105 subunit phosphorylated 2 (human), hNFKB1/Phos:2

organism-modification


PR:000064699 nuclear factor NF-kappa-B p105 subunit phosphorylated and ubiquitinated 1 (human), hNFKB1/PhosUbiq:1

organism-modification


PR:000072853 nuclear factor NF-kappa-B p105 subunit deaminated 1 (human), hNFKB1/Deam:1

organism-modification


PR:000075491 nuclear factor NF-kappa-B p105 subunit cysteinylated 1 (human), hNFKB1/Cyst:1

organism-modification


PR:000080523 nuclear factor NF-kappa-B p105 subunit deaminated 2 (human), hNFKB1/Deam:2

organism-modification


PR:000083954 nuclear factor NF-kappa-B p105 subunit deaminated 3 (human), hNFKB1/Deam:3

organism-gene


PR:P25799 nuclear factor NF-kappa-B p105 subunit (mouse), mNFKB1

organism-sequence


PR:P25799-1 nuclear factor NF-kappa-B p105 subunit isoform 1 (mouse), mNFKB1/iso:1

organism-modification


PR:000028540 nuclear factor NF-kappa-B p50 subunit (mouse), mNFKBp50

Yes
organism-sequence


PR:P25799-2 nuclear factor NF-kappa-B p105 subunit isoform m2 (mouse), mNFKB1/iso:m2

organism-sequence


PR:P25799-3 nuclear factor NF-kappa-B p105 subunit isoform m3 (mouse), mNFKB1/iso:m3

organism-sequence


PR:P25799-4 nuclear factor NF-kappa-B p105 subunit isoform m4 (mouse), mNFKB1/iso:m4

organism-sequence


PR:P25799-5 nuclear factor NF-kappa-B p105 subunit isoform m5 (mouse), mNFKB1/iso:m5

organism-sequence


PR:P25799-6 nuclear factor NF-kappa-B p105 subunit isoform m6 (mouse), mNFKB1/iso:m6

organism-sequence


PR:P25799-7 nuclear factor NF-kappa-B p105 subunit isoform m7 (mouse), mNFKB1/iso:m7

organism-gene


PR:Q04861 nuclear factor NF-kappa-B p105 subunit (chicken), chick-NFKB1

organism-sequence


PR:Q04861-1 nuclear factor NF-kappa-B p105 subunit isoform 1 (chicken), chick-NFKB1/iso:1

organism-sequence


PR:Q04861-2 nuclear factor NF-kappa-B p105 subunit isoform 2 (chicken), chick-NFKB1/iso:2

organism-sequence


PR:Q04861-3 nuclear factor NF-kappa-B p105 subunit isoform 3 (chicken), chick-NFKB1/iso:3

organism-gene


PR:Q63369 nuclear factor NF-kappa-B p105 subunit (rat), rNFKB1

organism-gene


PR:Q94527 nuclear factor NF-kappa-B p110 subunit (fruit fly), fly-NFKB1

organism-sequence


PR:Q94527-1 nuclear factor NF-kappa-B p110 subunit isoform Major (fruit fly), fly-NFKB1/iso:Major

organism-sequence


PR:Q94527-2 nuclear factor NF-kappa-B p110 subunit isoform Maternal (fruit fly), fly-NFKB1/iso:Maternal

sequence


PR:000001755 nuclear factor NF-kappa-B p105 subunit isoform 1, NFKB1/iso:1

organism-sequence


PR:P25799-1 nuclear factor NF-kappa-B p105 subunit isoform 1 (mouse), mNFKB1/iso:1

organism-modification


PR:000028540 nuclear factor NF-kappa-B p50 subunit (mouse), mNFKBp50

Yes
modification


PR:000001757 nuclear factor NF-kappa-B p50 subunit, NFKBp50

organism-modification


PR:000028540 nuclear factor NF-kappa-B p50 subunit (mouse), mNFKBp50

Yes
organism-modification


PR:000035834 nuclear factor NF-kappa-B p50 subunit (human), hNFKBp50
Yes
Yes
sequence


PR:000001758 nuclear factor NF-kappa-B p105 subunit isoform 2, NFKB1/iso:2

organism-sequence


PR:P19838-1 nuclear factor NF-kappa-B p105 subunit isoform 1 (human), hNFKB1/iso:1

modification


PR:000001759 nuclear factor NF-kappa-B p105 subunit isoform 2 phosphorylated form, NFKB1/iso:2/PhosRes+

modification


PR:000001760 nuclear factor NF-kappa-B p105 subunit isoform 2 phosphorylated 1, NFKB1/iso:2/Phos:1

modification


PR:000001762 nuclear factor NF-kappa-B p105 subunit isoform 2 phosphorylated 2, NFKB1/iso:2/Phos:2

sequence


PR:000001761 nuclear factor NF-kappa-B p105 subunit isoform 3, NFKB1/iso:3

organism-sequence


PR:P19838-2 nuclear factor NF-kappa-B p105 subunit isoform 2 (human), hNFKB1/iso:2

modification


PR:000018519 nuclear factor NF-kappa-B p105 subunit proteolytic cleavage product, NFKB1/ClvPrd

modification


PR:000001757 nuclear factor NF-kappa-B p50 subunit, NFKBp50

organism-modification


PR:000028540 nuclear factor NF-kappa-B p50 subunit (mouse), mNFKBp50

Yes
organism-modification


PR:000035834 nuclear factor NF-kappa-B p50 subunit (human), hNFKBp50
Yes
Yes
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NFKB1 forms found in complexes   

NFKB1 Component
 Complexes
PR:000028540 mNFKBp50 PR:000028542 NF-kappaB p50/p65 complex (mouse)
PR:000035834 hNFKBp50 PR:000035835 NF-kappaB p50/p65 complex (human)
PR:P19838 hNFKB1 PR:000028444 NFKB p105:TPL2:ABIN2 (human)
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000035834 hNFKBp50
UniProtKB:P19838, 1-433 | UniProtKB:P19838-1, 1-433 | NF-KAPPA-B P50 (human) | NFKB1 p50 (human) | PRO_0000030311 | p50 (human) (BROAD)
"A nuclear factor NF-kappa-B p50 subunit in human. Example: UniProtKB:P19838-1, 1-433." [PRO:DNx, UniProtKB:P19838]		 acts_upstream_of_or_withinGO:0034142 toll-like receptor 4 signaling pathway Reactome:REACT_6894