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Protein Ontology report - Bcl2-associated agonist of cell death
PR:000002184 - http://purl.obolibrary.org/obo/PR_000002184
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000002184   
  PRO nameBcl2-associated agonist of cell death 
  Synonyms
PRO-Short-label: EXACT:BAD
Gene-based: RELATED:BBC6 | BCL2L8
Other: EXACT:Bcl-2-binding component 6 | Bcl-2-like protein 8 | bcl-XL/Bcl-2-associated death promoter | Bcl2 antagonist of cell death | Bcl2-L-8
  Definition"A protein that is a translation product of the human BAD gene or a 1:1 ortholog thereof." [PRO:WCB] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 3                                        
         Sequence3                                                  Organism-Sequence 5                                        
         Modification13                                                  Organism-Modification 15                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
PIRSF:PIRSF023966
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000002184 Bcl2-associated agonist of cell death, BAD

organism-gene


PR:O35147 Bcl2-associated agonist of cell death (rat), rBAD

organism-sequence


PR:O35147-1 Bcl2-associated agonist of cell death isoform Alpha (rat), rBAD/iso:Alpha
Yes
organism-modification


PR:000026134 Bcl2-associated agonist of cell death isoform 1 phosphorylated 3 (rat), rBAD/iso:1/Phos:3
Yes
organism-modification


PR:000044748 Bcl2-associated agonist of cell death isoform 1 unmodified form (rat), rBAD/iso:1/UnMod
Yes
organism-sequence


PR:O35147-2 Bcl2-associated agonist of cell death isoform Beta (rat), rBAD/iso:Beta
Yes
organism-gene


PR:Q61337 Bcl2-associated agonist of cell death (mouse), mBAD

organism-sequence


PR:Q3U9H3 Bcl2-associated agonist of cell death isoform 2 (mouse), mBAD/iso:2

organism-sequence


PR:Q61337-1 Bcl2-associated agonist of cell death isoform 1 (mouse), mBAD/iso:1

organism-modification


PR:000026133 Bcl2-associated agonist of cell death isoform 1 phosphorylated 2 (mouse), mBAD/iso:1/Phos:2
Yes
organism-modification


PR:000026135 Bcl2-associated agonist of cell death isoform 1 phosphorylated 4 (mouse), mBAD/iso:1/Phos:4
Yes
organism-modification


PR:000026136 Bcl2-associated agonist of cell death isoform 1 phosphorylated 5 (mouse), mBAD/iso:1/Phos:5
Yes
organism-modification


PR:000026137 Bcl2-associated agonist of cell death isoform 1 phosphorylated 6 (mouse), mBAD/iso:1/Phos:6
Yes
organism-modification


PR:000026138 Bcl2-associated agonist of cell death isoform 1 phosphorylated 7 (mouse), mBAD/iso:1/Phos:7

organism-modification


PR:000026139 Bcl2-associated agonist of cell death isoform 1 phosphorylated 8 (mouse), mBAD/iso:1/Phos:8
Yes
organism-modification


PR:000026167 Bcl2-associated agonist of cell death isoform 1 phosphorylated 1 (mouse), mBAD/iso:1/Phos:1
Yes
organism-modification


PR:000037809 Bcl2-associated agonist of cell death isoform 1 unphosphorylated 1 (mouse), mBAD/iso:1/UnPhos:1

organism-modification


PR:000044747 Bcl2-associated agonist of cell death isoform 1 unmodified form (mouse), mBAD/iso:1/UnMod
Yes
organism-gene


PR:Q92934 Bcl2-associated agonist of cell death (human), hBAD

organism-sequence


PR:Q92934-1 Bcl2-associated agonist of cell death isoform 1 (human), hBAD/iso:1

organism-modification


PR:000026140 Bcl2-associated agonist of cell death isoform 2 phosphorylated 1 (human), hBAD/iso:2/Phos:1
Yes
organism-modification


PR:000044749 Bcl2-associated agonist of cell death isoform 2 unmodified form (human), hBAD/iso:2/UnMod
Yes
organism-modification


PR:000046455 Bcl2-associated agonist of cell death phosphorylated 2 (human), hBAD/Phos:2

organism-modification


PR:000046456 Bcl2-associated agonist of cell death phosphorylated 3 (human), hBAD/Phos:3

sequence


PR:000002280 Bcl2-associated agonist of cell death isoform 1, BAD/iso:1

organism-sequence


PR:O35147-1 Bcl2-associated agonist of cell death isoform Alpha (rat), rBAD/iso:Alpha
Yes
organism-modification


PR:000026134 Bcl2-associated agonist of cell death isoform 1 phosphorylated 3 (rat), rBAD/iso:1/Phos:3
Yes
organism-modification


PR:000044748 Bcl2-associated agonist of cell death isoform 1 unmodified form (rat), rBAD/iso:1/UnMod
Yes
organism-sequence


PR:Q61337-1 Bcl2-associated agonist of cell death isoform 1 (mouse), mBAD/iso:1

organism-modification


PR:000026133 Bcl2-associated agonist of cell death isoform 1 phosphorylated 2 (mouse), mBAD/iso:1/Phos:2
Yes
organism-modification


PR:000026135 Bcl2-associated agonist of cell death isoform 1 phosphorylated 4 (mouse), mBAD/iso:1/Phos:4
Yes
organism-modification


PR:000026136 Bcl2-associated agonist of cell death isoform 1 phosphorylated 5 (mouse), mBAD/iso:1/Phos:5
Yes
organism-modification


PR:000026137 Bcl2-associated agonist of cell death isoform 1 phosphorylated 6 (mouse), mBAD/iso:1/Phos:6
Yes
organism-modification


PR:000026138 Bcl2-associated agonist of cell death isoform 1 phosphorylated 7 (mouse), mBAD/iso:1/Phos:7

organism-modification


PR:000026139 Bcl2-associated agonist of cell death isoform 1 phosphorylated 8 (mouse), mBAD/iso:1/Phos:8
Yes
organism-modification


PR:000026167 Bcl2-associated agonist of cell death isoform 1 phosphorylated 1 (mouse), mBAD/iso:1/Phos:1
Yes
organism-modification


PR:000037809 Bcl2-associated agonist of cell death isoform 1 unphosphorylated 1 (mouse), mBAD/iso:1/UnPhos:1

organism-modification


PR:000044747 Bcl2-associated agonist of cell death isoform 1 unmodified form (mouse), mBAD/iso:1/UnMod
Yes
modification


PR:000002843 Bcl2-associated agonist of cell death isoform 1 unmodified form, BAD/iso:1/UnMod

organism-modification


PR:000044747 Bcl2-associated agonist of cell death isoform 1 unmodified form (mouse), mBAD/iso:1/UnMod
Yes
organism-modification


PR:000044748 Bcl2-associated agonist of cell death isoform 1 unmodified form (rat), rBAD/iso:1/UnMod
Yes
modification


PR:000003084 Bcl2-associated agonist of cell death isoform 1 phosphorylated form, BAD/iso:1/PhosRes+

modification


PR:000003085 Bcl2-associated agonist of cell death isoform 1 phosphorylated 1, BAD/iso:1/Phos:1

organism-modification


PR:000026167 Bcl2-associated agonist of cell death isoform 1 phosphorylated 1 (mouse), mBAD/iso:1/Phos:1
Yes
modification


PR:000003086 Bcl2-associated agonist of cell death isoform 1 phosphorylated 2, BAD/iso:1/Phos:2

organism-modification


PR:000026133 Bcl2-associated agonist of cell death isoform 1 phosphorylated 2 (mouse), mBAD/iso:1/Phos:2
Yes
modification


PR:000003087 Bcl2-associated agonist of cell death isoform 1 phosphorylated 3, BAD/iso:1/Phos:3

organism-modification


PR:000026134 Bcl2-associated agonist of cell death isoform 1 phosphorylated 3 (rat), rBAD/iso:1/Phos:3
Yes
modification


PR:000003233 Bcl2-associated agonist of cell death isoform 1 phosphorylated 4, BAD/iso:1/Phos:4

organism-modification


PR:000026135 Bcl2-associated agonist of cell death isoform 1 phosphorylated 4 (mouse), mBAD/iso:1/Phos:4
Yes
modification


PR:000003238 Bcl2-associated agonist of cell death isoform 1 phosphorylated 5, BAD/iso:1/Phos:5

organism-modification


PR:000026136 Bcl2-associated agonist of cell death isoform 1 phosphorylated 5 (mouse), mBAD/iso:1/Phos:5
Yes
modification


PR:000003269 Bcl2-associated agonist of cell death isoform 1 phosphorylated 6, BAD/iso:1/Phos:6

organism-modification


PR:000026137 Bcl2-associated agonist of cell death isoform 1 phosphorylated 6 (mouse), mBAD/iso:1/Phos:6
Yes
modification


PR:000025849 Bcl2-associated agonist of cell death isoform 1 phosphorylated 7, BAD/iso:1/Phos:7

organism-modification


PR:000026138 Bcl2-associated agonist of cell death isoform 1 phosphorylated 7 (mouse), mBAD/iso:1/Phos:7

modification


PR:000025850 Bcl2-associated agonist of cell death isoform 1 phosphorylated 8, BAD/iso:1/Phos:8

organism-modification


PR:000026139 Bcl2-associated agonist of cell death isoform 1 phosphorylated 8 (mouse), mBAD/iso:1/Phos:8
Yes
sequence


PR:000002281 Bcl2-associated agonist of cell death isoform 2, BAD/iso:2

organism-sequence


PR:Q3U9H3 Bcl2-associated agonist of cell death isoform 2 (mouse), mBAD/iso:2

organism-sequence


PR:Q92934-1 Bcl2-associated agonist of cell death isoform 1 (human), hBAD/iso:1

organism-modification


PR:000026140 Bcl2-associated agonist of cell death isoform 2 phosphorylated 1 (human), hBAD/iso:2/Phos:1
Yes
organism-modification


PR:000044749 Bcl2-associated agonist of cell death isoform 2 unmodified form (human), hBAD/iso:2/UnMod
Yes
modification


PR:000002844 Bcl2-associated agonist of cell death isoform 2 unmodified form, BAD/iso:2/UnMod

organism-modification


PR:000044749 Bcl2-associated agonist of cell death isoform 2 unmodified form (human), hBAD/iso:2/UnMod
Yes
modification


PR:000003231 Bcl2-associated agonist of cell death isoform 2 phosphorylated form, BAD/iso:2/PhosRes+

modification


PR:000003232 Bcl2-associated agonist of cell death isoform 2 phosphorylated 1, BAD/iso:2/Phos:1

organism-modification


PR:000026140 Bcl2-associated agonist of cell death isoform 2 phosphorylated 1 (human), hBAD/iso:2/Phos:1
Yes
sequence


PR:000003251 Bcl2-associated agonist of cell death isoform 3, BAD/iso:3

organism-sequence


PR:O35147-2 Bcl2-associated agonist of cell death isoform Beta (rat), rBAD/iso:Beta
Yes
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000026133 mBAD/iso:1/Phos:2
UniProtKB:Q61337-1, Ser-112/Ser-136/Ser-155, MOD:00046
"A Bcl2-associated agonist of cell death isoform 1 phosphorylated 2 in mouse. UniProtKB:Q61337-1, Ser-112/Ser-136/Ser-155, MOD:00046." [PMID:10880354, PMID:10949026, PRO:JAN]		 acts_upstream_of_or_withinGO:0043066 negative regulation of apoptotic process PMID:10949026
enablesNOT GO:0005515 protein binding with PR:000003237 fam:14-3-3 PMID:10949026
NOT GO:0005515 protein binding with PR:P63101-1 PMID:10949026
NOT GO:0005515 protein binding with PR:Q64373-1 PMID:10949026
NOT GO:0005515 protein binding with PR:Q07817-1 PMID:10949026
PR:000026134 rBAD/iso:1/Phos:3
UniProtKB:O35147-1, Ser-112, MOD:00046
"A Bcl2-associated agonist of cell death isoform 1 phosphorylated 3 in rat. UniProtKB:O35147-1, Ser-112, MOD:00046." [PMID:10195903, PMID:10597268, PRO:JAN]		 enablesdecreased GO:0005515 protein binding with PR:P53563-1 PMID:10195903
GO:0019902 phosphatase binding PMID:10195903
located_inGO:0005829 cytosol PMID:10195903
PR:000026135 mBAD/iso:1/Phos:4
UniProtKB:Q61337-1, Thr-201, MOD:00047
"A Bcl2-associated agonist of cell death isoform 1 phosphorylated 4 in mouse. UniProtKB:Q61337-1, Thr-201, MOD:00047." [PMID:14967141, PRO:JAN]		 acts_upstream_of_or_withinGO:0043066 negative regulation of apoptotic process PMID:14967141
enablesdecreased GO:0005515 protein binding with PR:Q64373-1 PMID:14967141
PR:000026136 mBAD/iso:1/Phos:5
UniProtKB:Q61337-1, Ser-136, MOD:00046
"A Bcl2-associated agonist of cell death isoform 1 phosphorylated 5 in mouse. UniProtKB:Q61337-1, Ser-136, MOD:00046." [PMID:12049737, PRO:JAN]		 enablesGO:0005515 protein binding with PR:P63101 KCIP-1 (mouse) PMID:12049737
PR:000026137 mBAD/iso:1/Phos:6
UniProtKB:Q61337-1, Ser-128/Ser-136, MOD:00046
"A Bcl2-associated agonist of cell death isoform 1 phosphorylated 6 in mouse. UniProtKB:Q61337-1, Ser-128/Ser-136, MOD:00046." [PMID:12049737, PRO:JAN]		 acts_upstream_of_or_withinGO:0051402 neuron apoptotic process PMID:12049737
PR:000026139 mBAD/iso:1/Phos:8
UniProtKB:Q61337-1, Ser-155, MOD:00046
"A Bcl2-associated agonist of cell death isoform 1 phosphorylated 8 in mouse. UniProtKB:Q61337-1, Ser-155, MOD:00046." [PMID:10880354, PRO:CNA]		 enablesGO:0071889 14-3-3 protein binding with PR:P61982 mYWHAG PMID:10880354
PR:000026140 hBAD/iso:2/Phos:1
UniProtKB:Q92934-1, Ser-75/Ser-99, MOD:00046
"A Bcl2-associated agonist of cell death isoform 2 phosphorylated 1 in human. UniProtKB:Q92934-1, Ser-75/Ser-99, MOD:00046." [PMID:10195903, PMID:16932738, PRO:JAN]		 enablesdecreased GO:0005515 protein binding with PR:Q07817-1 PMID:10195903
GO:0005829 cytosol PMID:10195903
GO:0019902 phosphatase binding PMID:10195903
GO:0071889 14-3-3 protein binding PMID:16932738
located_inGO:0005829 cytosol PMID:10195903
PR:000026167 mBAD/iso:1/Phos:1
UniProtKB:Q61337-1, Ser-112/Ser-136, MOD:00046
"A Bcl2-associated agonist of cell death isoform 1 phosphorylated 1 in mouse. UniProtKB:Q61337-1, Ser-112/Ser-136, MOD:00046." [PMID:10949026, PMID:8929531, PMID:9346240, PRO:JAN]		 enablesdecreased GO:0005515 protein binding with PR:P62258-1 PMID:12049737
decreased GO:0005515 protein binding with PR:Q07817-1 PMID:12049737
decreased GO:0005515 protein binding with PR:Q9CQV8 KCIP-1 (mouse) PMID:12049737
decreased GO:0005515 protein binding with PR:P63101 KCIP-1 (mouse) PMID:12049737
PR:000044747 mBAD/iso:1/UnMod

"A Bcl2-associated agonist of cell death isoform 1 unmodified form in mouse." [PRO:DNx]		 acts_upstream_of_or_withinGO:0006915 apoptotic process PMID:15280015
enablesGO:0005515 protein binding with PR:P04049 cRaf (human) PMID:17011751
GO:0005515 protein binding with PR:P06803-2 PMID:17011751
GO:0005515 protein binding with PR:P15056 BRAF PMID:17011751
GO:0005515 protein binding with PR:Q04759 hPRKCQ PMID:17011751
located_inGO:0031966 mitochondrial membrane PMID:15280015
PR:000044748 rBAD/iso:1/UnMod

"A Bcl2-associated agonist of cell death isoform 1 unmodified form in rat." [PRO:DNx]		 enablesGO:0005515 protein binding with PR:P53563-1 PMID:10195903
decreased GO:0019902 phosphatase binding relative to PR:000026134 rBAD/iso:1/Phos:3 PMID:10195903
located_inGO:0005739 mitochondrion PMID:10195903
PR:000044749 hBAD/iso:2/UnMod

"A Bcl2-associated agonist of cell death isoform 2 unmodified form in human." [PRO:DNx]		 enablesGO:0005515 protein binding with PR:Q07817-1 PMID:10195903
located_inGO:0005739 mitochondrion PMID:10195903
PR:O35147-1 rBAD/iso:Alpha

"A Bcl2-associated agonist of cell death isoform 1 that is encoded in the genome of rat." [PRO:JAN]		 acts_upstream_of_or_withinGO:0043525 positive regulation of neuron apoptotic process PMID:11161472
enablesGO:0005515 protein binding with PR:O88996-1 PMID:11161472
PR:O35147-2 rBAD/iso:Beta

"A Bcl2-associated agonist of cell death isoform 3 that is encoded in the genome of rat." [PRO:JAN]		 acts_upstream_of_or_withinGO:0043525 positive regulation of neuron apoptotic process PMID:11161472
enablesGO:0005515 protein binding with PR:O88996-1 PMID:11161472