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Protein Ontology report - serine/threonine-protein kinase mTOR
PR:000003041 - http://purl.obolibrary.org/obo/PR_000003041
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000003041   
  PRO nameserine/threonine-protein kinase mTOR 
  Synonyms
PRO-Short-label: EXACT:MTOR
Gene-based: RELATED:FRAP | FRAP1 | FRAP2 | RAFT1 | RAPT1
Other: EXACT:FK506-binding protein 12-rapamycin complex-associated protein 1 | FKBP12-rapamycin complex-associated protein | mammalian target of rapamycin | mechanistic target of rapamycin | mTOR | rapamycin target protein 1
  Definition"A protein that is a translation product of the human MTOR gene or a 1:1 ortholog thereof." [PRO:CL] 
  PRO Categorygene 
  ParentPR:000000001 protein
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene1                                                  Organism-Gene 7                                        
         Sequence1                                                  Organism-Sequence 7                                        
         Modification0                                                  Organism-Modification 6                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
IUPHARobj:2109
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Ann. Has Annotation?

Comp. In Complex?
gene


PR:000003041 serine/threonine-protein kinase mTOR, MTOR

organism-gene


PR:P42345 serine/threonine-protein kinase mTOR (human), hMTOR
Yes
organism-sequence


PR:P42345-1 serine/threonine-protein kinase mTOR isoform 1 (human), hMTOR/iso:1

organism-modification


PR:000045781 serine/threonine-protein kinase mTOR phosphorylated 1 (human), hMTOR/Phos:1

organism-modification


PR:000068288 serine/threonine-protein kinase mTOR deaminated 1 (human), hMTOR/Deam:1

organism-modification


PR:000073464 serine/threonine-protein kinase mTOR deaminated 2 (human), hMTOR/Deam:2

organism-modification


PR:000081494 serine/threonine-protein kinase mTOR cysteinylated 1 (human), hMTOR/Cyst:1

organism-gene


PR:P42346 serine/threonine-protein kinase mTOR (rat), rMTOR

organism-sequence


PR:P42346-1 serine/threonine-protein kinase mTOR isoform 1 (rat), rMTOR/iso:1

organism-gene


PR:Q86C65 serine/threonine-protein kinase tor (Dictyostelium discoideum), Dicty-MTOR

organism-gene


PR:Q95Q95 target of rapamycin homolog (worm), MTOR (worm)

organism-sequence


PR:Q95Q95-1 target of rapamycin homolog isoform a (worm), MTOR/iso:a (worm)

organism-sequence


PR:Q95Q95-2 target of rapamycin homolog isoform b (worm), MTOR/iso:b (worm)

organism-gene


PR:Q9FR53 serine/threonine-protein kinase TOR (Arabidopsis thaliana), At-MTOR

organism-sequence


PR:Q9FR53-1 serine/threonine-protein kinase TOR isoform 1 (Arabidopsis thaliana), At-MTOR/iso:1

organism-gene


PR:Q9JLN9 serine/threonine-protein kinase mTOR (mouse), mMTOR

organism-sequence


PR:Q9JLN9-1 serine/threonine-protein kinase mTOR isoform 1 (mouse), mMTOR/iso:1

organism-modification


PR:000050320 serine/threonine-protein kinase mTOR isoform 1 phosphorylated 1 (mouse), mMTOR/iso:1/Phos:1

organism-modification


PR:000050321 serine/threonine-protein kinase mTOR isoform 1 unphosphorylated 1 (mouse), mMTOR/iso:1/UnPhos:1

organism-sequence


PR:Q9JLN9-2 serine/threonine-protein kinase mTOR isoform m2 (mouse), mMTOR/iso:m2

organism-gene


PR:Q9VK45 serine/threonine-protein kinase mTor (fruit fly), fly-MTOR

sequence


PR:000039438 serine/threonine-protein kinase mTOR isoform 1, MTOR/iso:1

organism-sequence


PR:P42345-1 serine/threonine-protein kinase mTOR isoform 1 (human), hMTOR/iso:1

organism-sequence


PR:P42346-1 serine/threonine-protein kinase mTOR isoform 1 (rat), rMTOR/iso:1

organism-sequence


PR:Q9JLN9-1 serine/threonine-protein kinase mTOR isoform 1 (mouse), mMTOR/iso:1

organism-modification


PR:000050320 serine/threonine-protein kinase mTOR isoform 1 phosphorylated 1 (mouse), mMTOR/iso:1/Phos:1

organism-modification


PR:000050321 serine/threonine-protein kinase mTOR isoform 1 unphosphorylated 1 (mouse), mMTOR/iso:1/UnPhos:1

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:P42345 hMTOR
FRAP | FRAP1 | FRAP2 | MTOR | RAFT1 | RAPT1 | FK506-binding protein 12-rapamycin complex-associated protein 1 (human) | FKBP12-rapamycin complex-associated protein (human) | mammalian target of rapamycin (human) | mechanistic target of rapamycin (human) | mTOR (human) | rapamycin and FKBP12 target 1 (human) | rapamycin target protein 1 (human)
"A serine/threonine-protein kinase mTOR that is encoded in the genome of human." [PRO:CL, UniProtKB:P42345]		 acts_upstream_of_or_withinGO:0006915 apoptotic process PMID:11602639
enablesGO:0005515 protein binding with PR:000035446 hTP53/iso:1/Phos:1 PMID:11602639
located_inGO:0005634 nucleus PMID:11602639