back to PRO homepage
  Home |   Linked Open Data |   Browse |  
Search

|   Statistics |   Download
 RACE-PRO
 PRO tracker
 Community
 PRO Consortium
 Publications
 Documentation

Protein Ontology report - IRF3/IRF7:p-tbk1/p-IKKE:ticam1:ticam2:activated TLR4 complex
PR:000028699 - http://purl.obolibrary.org/obo/PR_000028699
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000028699   
  PRO nameIRF3/IRF7:p-tbk1/p-IKKE:ticam1:ticam2:activated TLR4 complex 
  Synonyms
Other: RELATED:activated TLR4:TRAM:TRIF:p-TBK1/p-IKKE:IRF3/IRF7
  Definition"A protein-containing complex that is composed of activated Toll-like receptor 4 (TLR4), Ticam2, Ticam1, a phosphorylated kinase tbk1 or IKK epsilon and the non-phosphorylated form of IRF3 or IRF7. IRF3 and IRF7 are recruited via phosphorylated tbk1 and IKK epsilon." [] 
  CommentRequested by=TLR. 
  PRO Categorycomplex 
  ParentG0032991 protein-containing complex
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Complex5                                                  Organism-Complex 4                                        
  Term Hierarchy
  Visualization
DAG: OLS:
Back to top
Protein Forms  Switch to Extended View   

Category  

PRO Form Name

Short Name

Ann. Has Annotation?

Comp. In Complex?
complex



PR:000028699 IRF3/IRF7:p-tbk1/p-IKKE:ticam1:ticam2:activated TLR4 complex

hTBK1/Phos:1


complex



PR:000036029 IRF3:p-tbk1:K63-poly-Ub-TRAF3:ticam1:ticam2:activated TLR4 complex

BTBD7/iso:3


organism-complex



PR:000036030 IRF3:p-tbk1:K63-poly-Ub-TRAF3:ticam1:ticam2:activated TLR4 complex (human)

BTBD7/iso:3

Yes

complex



PR:000036033 IRF7:p-tbk1:K63-poly-Ub-TRAF3:ticam1:ticam2:activated TLR4 complex

hTRAF3/K63polyUbiq+


organism-complex



PR:000036034 IRF7:p-tbk1:K63-poly-Ub-TRAF3:ticam1:ticam2:activated TLR4 complex (human)

hTRAF3/K63polyUbiq+

Yes

complex



PR:000036035 IRF3:p-IKKE:K63-poly-Ub-TRAF3:ticam1:ticam2:activated TLR4 complex

hTRAF3/K63polyUbiq+


organism-complex



PR:000036036 IRF3:p-IKKE:K63-poly-Ub-TRAF3:ticam1:ticam2:activated TLR4 complex (human)

hTRAF3/K63polyUbiq+

Yes

complex



PR:000036037 IRF7:p-IKKE:K63-poly-Ub-TRAF3:ticam1:ticam2:activated TLR4 complex

hTRAF3/K63polyUbiq+


organism-complex



PR:000036038 IRF7:p-IKKE:K63-poly-Ub-TRAF3:ticam1:ticam2:activated TLR4 complex (human)

hTRAF3/K63polyUbiq+

Yes

Back to top
Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000036030 BTBD7/iso:3 acts_upstream_of_or_withinGO:0002756 MyD88-independent toll-like receptor signaling pathway Reactome:REACT_6809
enablesGO:0004674 protein serine/threonine kinase activity Reactome:REACT_27000
located_inGO:0010008 endosome membrane Reactome:REACT_27000
PR:000036034 hTRAF3/K63polyUbiq+ acts_upstream_of_or_withinGO:0002756 MyD88-independent toll-like receptor signaling pathway Reactome:REACT_6809
enablesGO:0004674 protein serine/threonine kinase activity Reactome:REACT_27000
located_inGO:0010008 endosome membrane Reactome:REACT_27000
PR:000036036 hTRAF3/K63polyUbiq+ acts_upstream_of_or_withinGO:0002756 MyD88-independent toll-like receptor signaling pathway Reactome:REACT_6809
enablesGO:0004674 protein serine/threonine kinase activity Reactome:REACT_27000
located_inGO:0010008 endosome membrane Reactome:REACT_27000
PR:000036038 hTRAF3/K63polyUbiq+ acts_upstream_of_or_withinGO:0002756 MyD88-independent toll-like receptor signaling pathway Reactome:REACT_6809
enablesGO:0004674 protein serine/threonine kinase activity Reactome:REACT_27000
located_inGO:0010008 endosome membrane Reactome:REACT_27000