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Protein Ontology report - K63-poly-Ub-TRAF3:ticam1:activated TLR4 complex (human)
PR:000036182 -
http://purl.obolibrary.org/obo/PR_000036182
Protein Forms
Annotations
Ontology Information
Show OBO stanza
/
GPI
PRO ID
PR:000036182
PRO name
K63-poly-Ub-TRAF3:ticam1:activated TLR4 complex (human)
Definition
"A protein-containing complex in human that is composed of TRAF3 linked to Lys-63 polyubiquitin, ticam1, and either activated Toll-like receptor 3 (TLR3) or activated Toll-like receptor 4 (TLR4) with ticam2." [PRO:DAN,
Reactome:R
-HSA-2213008]
PRO Category
organism-complex
Parent
G0032991
protein-containing complex
Taxon
NCBITaxon:9606
Homo sapiens
Terms by PRO Category
Organism-Independent
Organism-Specific
Category
Number of Terms
Category
Number of Terms
Complex
0
Organism-Complex
3
Term Hierarchy
Visualization
DAG:
OLS:
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Protein Forms
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Extended View
Category
PRO Form Name
Ann.
Has Annotation?
Comp.
In Complex?
organism-complex
PR:000036182
K63-poly-Ub-TRAF3:ticam1:activated TLR4 complex (human), hACTB/Ac:1
organism-complex
PR:000036041
K63-poly-Ub-TRAF3:ticam1:ticam2:activated TLR4 complex (human), mK63polyUbiq
organism-complex
PR:000037315
K63-poly-Ub-TRAF3:ticam1:activated TLR3 complex (human), hTLR3/SigPep-
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Functional Annotation (PRO-centric view)
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GO Centric View
PRO Term
GO Annotation
Evidence
PR:000036041
mK63polyUbiq
K63-poly-Ub-TRAF3:TRIF:TRAM:activated TLR4 (human)
"A K63-poly-Ub-TRAF3:ticam1:ticam2:activated TLR4 complex whose components are encoded in the genome of human." [PMID:16306936, PMID:16306937, Reactome:R-HSA-2213008]
acts_upstream_of_or_within
GO:0002756
MyD88-independent toll-like receptor signaling pathway
Reactome:REACT_6809
located_in
GO:0010008
endosome membrane
Reactome:REACT_124855
PR:000037315
hTLR3/SigPep-
K63-poly-Ub-TRAF3:TRIF:activated TLR3 (human)
"A K63-poly-Ub-TRAF3:ticam1:activated TLR3 complex whose components are encoded in the genome of human." [PMID:16306936, PMID:16306937, PRO:DAN, PRO:VS, Reactome:R-HSA-2213008]
acts_upstream_of_or_within
GO:0002756
MyD88-independent toll-like receptor signaling pathway
Reactome:REACT_6783
GO:0034138
toll-like receptor 3 signaling pathway
Reactome:REACT_6783
located_in
GO:0010008
endosome membrane
Reactome:REACT_6783