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Protein Ontology report - K63-pUb-rip1:ticam1:activated TLR3/TLR4 complex (human)
PR:000036191 -
http://purl.obolibrary.org/obo/PR_000036191
Protein Forms
Annotations
Ontology Information
Show OBO stanza
/
GPI
PRO ID
PR:000036191
PRO name
K63-pUb-rip1:ticam1:activated TLR3/TLR4 complex (human)
Definition
"A protein-containing complex in human that is composed of K63-pUb-rip1, ticam1, and either activated Toll-like receptor 3 (TLR3) or activated Toll-like receptor 4 (TLR4) with ticam2." [PRO:DAN,
Reactome:R
-HSA-937016]
PRO Category
organism-complex
Parent
G0032991
protein-containing complex
Taxon
NCBITaxon:9606
Homo sapiens
Terms by PRO Category
Organism-Independent
Organism-Specific
Category
Number of Terms
Category
Number of Terms
Complex
0
Organism-Complex
3
Term Hierarchy
Visualization
DAG:
OLS:
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Protein Forms
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Extended View
Category
PRO Form Name
Ann.
Has Annotation?
Comp.
In Complex?
organism-complex
PR:000036191
K63-pUb-rip1:ticam1:activated TLR3/TLR4 complex (human), hACTB/Ac:1
organism-complex
PR:000036049
K63-pUb-rip1:ticam1:ticam2:activated TLR4 complex (human), mK63polyUbiq
organism-complex
PR:000037362
K63-pUb-rip1:ticam1:activated TLR3 complex (human), ARAP3/iso:1
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Functional Annotation (PRO-centric view)
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GO Centric View
PRO Term
GO Annotation
Evidence
PR:000036049
mK63polyUbiq
activated TLR4:TRIF:K63-pUb-RIP1 (human)
"A K63-pUb-rip1:ticam1:ticam2:activated TLR4 complex whose components are encoded in the genome of human." [PMID:15064760, PMID:15814722, PMID:16115877, Reactome:R-HSA-937016]
acts_upstream_of_or_within
GO:0002756
MyD88-independent toll-like receptor signaling pathway
Reactome:REACT_6809
located_in
GO:0010008
endosome membrane
Reactome:REACT_25755
PR:000037362
ARAP3/iso:1
activated TLR3:TRIF:K63-pUb-RIP1 (human)
"A K63-pUb-rip1:ticam1:activated TLR3 complex whose components are encoded in the genome of human." [PMID:15064760, PMID:15814722, PMID:16115877, PRO:VS, Reactome:R-HSA-937016]
acts_upstream_of_or_within
GO:0002756
MyD88-independent toll-like receptor signaling pathway
Reactome:REACT_6783
GO:0034138
toll-like receptor 3 signaling pathway
Reactome:REACT_6783
located_in
GO:0010008
endosome membrane
Reactome:REACT_6783