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Protein Ontology report - IRF3:p-IKKE:K63-poly-Ub-TRAF3:ticam1:activated TLR3 complex
PR:000037357 - http://purl.obolibrary.org/obo/PR_000037357
 
  Protein Forms  Annotations      
Ontology Information Show OBO stanza
  PRO ID
PR:000037357   
  PRO nameIRF3:p-IKKE:K63-poly-Ub-TRAF3:ticam1:activated TLR3 complex 
  Synonyms
Other: RELATED:activated TLR3:TRIF:K63-poly-Ub-TRAF3:p-IKK epsilon:IRF3
  Definition"A protein-containing complex that is composed of activated Toll-like receptor 3 (TLR3), Ticam1 (TRIF), TRAF3 linked to Lys-63 polyubiquitin, phosphorylated IKK epsilon and unphosphosrylated IRF3." [PMID:14517278, PMID:14739303, PMID:16281057
  CommentRequested by=TLR. 
  PRO Categorycomplex 
  ParentG0032991
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Complex1                                                  Organism-Complex 1                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Protein Forms  Switch to Extended View   

Category  

PRO Form Name

Ann. Has Annotation?

Comp. In Complex?
complex



PR:000037357 IRF3:p-IKKE:K63-poly-Ub-TRAF3:ticam1:activated TLR3 complex, ARAP3/iso:1


organism-complex



PR:000037358 IRF3:p-IKKE:K63-poly-Ub-TRAF3:ticam1:activated TLR3 complex (human), ARAP3/iso:1

Yes

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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000037358
ARAP3/iso:1
activated TLR3:TRIF:K63-poly-Ub-TRAF3:p-TBK1/p-IKK epsilon:IRF3
acts_upstream_of_or_withinGO:0002756 MyD88-independent toll-like receptor signaling pathway Reactome:REACT_6783
GO:0034138 toll-like receptor 3 signaling pathway Reactome:REACT_6783
located_inGO:0010008 endosome membrane Reactome:REACT_6783