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Protein Ontology report - TIRAP:PIP2:BTK:activated TLR4 complex (human)
PR:000037447 -
Ontology Information Show OBO stanza / PAF / GPI
  PRO nameTIRAP:PIP2:BTK:activated TLR4 complex (human) 
Other: EXACT:MAL:PI(4,5)P2:BTK:activated TLR4 (human)
RELATED:MAL:BTK:activated TLR4 (human)
  Definition"A TIRAP:PIP2:BTK:activated TLR4 complex in human that is composed of PI(4,5)P2, tyrosine unphosphorylated TIRAP/MAL, BTK, TLR4, MD2, CD14, LPS." [PMID:11544529, PMID:12724322, PMID:12888566, Reactome:R-HSA-2201331
  PRO Categoryorganism-complex 
  ParentPR:000037472 TIRAP:PIP2:BTK:activated TLR4 complex
  TaxonNCBITaxon:9606 Homo sapiens
  Term Hierarchy
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000037447 FGF14/iso:3 acts_upstream_of_or_withinGO:0002755 MyD88-dependent toll-like receptor signaling pathway Reactome:REACT_120882
GO:0034142 toll-like receptor 4 signaling pathway Reactome:REACT_120882
enablesGO:0004713 protein tyrosine kinase activity Reactome:REACT_120882
located_inGO:0005886 plasma membrane Reactome:REACT_120882