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Protein Ontology report - genome polyprotein (Dengue virus 2 Thailand/NGS-C/1944)

PR:P14340 - http://purl.obolibrary.org/obo/PR_P14340

Protein Forms

Annotations

Ontology Information

Show OBO stanza

GPI

PRO ID

PR:P14340

PRO name

genome polyprotein (Dengue virus 2 Thailand/NGS-C/1944)

Synonyms

PRO-Short-label:

EXACT:

polyprot (DEN2N)

Definition

"A dengue virus genome polyprotein that is encoded in the genome of Dengue virus 2 Thailand/NGS-C/1944." [PRO:ES]

PRO Category

organism-gene

Parent

PR:000036197 viral protein
PR:000036816 dengue virus genome polyprotein

Taxon

NCBITaxon:11065 Dengue virus 2 Thailand/NGS-C/1944

Terms by PRO Category

Organism-Independent		Organism-Specific
Category	Number of Terms	Category	Number of Terms
Gene	0	Organism-Gene	1
Sequence	0	Organism-Sequence	0
Modification	0	Organism-Modification	9

Term Hierarchy
Visualization

DAG:

OLS:

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Related Cross References
Db identifiers	UniProtKB:P14340

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Protein Forms

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Category

PRO Form Name

Ann. Has Annotation?

Comp. In Complex?

organism-gene

PR:P14340 genome polyprotein (Dengue virus 2 Thailand/NGS-C/1944), polyprot (DEN2N)

organism-modification

PR:000044758 NS1 (Dengue virus 2 Thailand/NGS-C/1944), NS1 (DEN2N)

Yes

organism-modification

PR:000044759 NS2A (Dengue virus 2 Thailand/NGS-C/1944), NS2A (DEN2N)

Yes

organism-modification

PR:000044761 NS2B (Dengue virus 2 Thailand/NGS-C/1944), NS2B (DEN2N)

Yes

organism-modification

PR:000044762 NS3 (Dengue virus 2 Thailand/NGS-C/1944), NS3 (DEN2N)

Yes

organism-modification

PR:000044763 NS4A (Dengue virus 2 Thailand/NGS-C/1944), NS4A (DEN2N)

Yes

organism-modification

PR:000044765 2K (Dengue virus 2 Thailand/NGS-C/1944), 2K (DEN2N)

Yes

organism-modification

PR:000044766 NS4B (Dengue virus 2 Thailand/NGS-C/1944), NS4B (DEN2N)

Yes

organism-modification

PR:000044768 NS5 (Dengue virus 2 Thailand/NGS-C/1944), NS5 (DEN2N)

Yes

organism-modification

PR:000044770 prM (Dengue virus 2 Thailand/NGS-C/1944), prM (DEN2N)

Yes

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Functional Annotation (PRO-centric view)

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PRO Term	GO Annotation		Evidence
PR:000044758 NS1 (DEN2N) UniProtKB:P14340, 776-1127, Asn-905/Asn-982, MOD:00160 \| PRO_0000037962, Asn-905/Asn-982, MOD:00160 "An NS1 in Dengue virus 2 Thailand/NGS-C/1944. UniProtKB:P14340, 776-1127, Asn-905/Asn-982, MOD:00160." [PRO:DNx]	acts_upstream_of_or_within	GO:0019079 viral genome replication	PMID:23408612
	acts_upstream_of_or_within	GO:0097281 immune complex formation	PMID:23408612
	located_in	GO:0019034 viral replication complex	PMID:23408612
PR:000044759 NS2A (DEN2N) UniProtKB:P14340, 1128-1345 \| PRO_0000037963 "An NS2A in Dengue virus 2 Thailand/NGS-C/1944. UniProtKB:P14340, 1128-1345." [PRO:DNx]	acts_upstream_of_or_within	GO:0019068 virion assembly	PMID:23408612
		GO:0019076 viral release from host cell	PMID:23408612
		GO:0019079 viral genome replication	PMID:23408612
	located_in	GO:0019034 viral replication complex	PMID:23408612
PR:000044761 NS2B (DEN2N) UniProtKB:P14340, 1346-1475 \| PRO_0000037964 "An NS2B in Dengue virus 2 Thailand/NGS-C/1944. UniProtKB:P14340, 1346-1475." [PRO:DNx]	acts_upstream_of_or_within	GO:1900005 positive regulation of serine-type endopeptidase activity	PMID:10744671
	enables	contributes_to GO:0008236 serine-type peptidase activity	PMID:10744671
PR:000044762 NS3 (DEN2N) UniProtKB:P14340, 1476-2093 \| PRO_0000037965 "An NS3 in Dengue virus 2 Thailand/NGS-C/1944. UniProtKB:P14340, 1476-2093." [PRO:DNx]	acts_upstream_of_or_within	GO:0019082 viral protein processing	PMID:10744671
	enables	GO:0003724 RNA helicase activity	PMID:10744671
		GO:0008236 serine-type peptidase activity	PMID:10744671
		GO:0017111 ribonucleoside triphosphate phosphatase activity	PMID:10744671
PR:000044763 NS4A (DEN2N) UniProtKB:P14340, 2094-2220 \| PRO_0000037966 "An NS4A in Dengue virus 2 Thailand/NGS-C/1944. UniProtKB:P14340, 2094-2220." [PRO:DNx]	acts_upstream_of_or_within	GO:0019079 viral genome replication	PMID:17276984
	located_in	GO:0019034 viral replication complex	PMID:17276984
PR:000044765 2K (DEN2N) UniProtKB:P14340, 2221-2243 \| PRO_0000261391 "A 2K in Dengue virus 2 Thailand/NGS-C/1944. UniProtKB:P14340, 2221-2243." [PRO:DNx]	acts_upstream_of_or_within	GO:0045051 protein insertion into ER membrane by internal uncleaved signal-anchor sequence	PMID:17276984
	enables	GO:0043495 protein-membrane adaptor activity	PMID:21810535
	located_in	GO:0016020 membrane	PMID:21810535
PR:000044766 NS4B (DEN2N) UniProtKB:P14340, 2244-2491 \| PRO_0000037967 "An NS4B in Dengue virus 2 Thailand/NGS-C/1944. UniProtKB:P14340, 2244-2491." [PRO:DNx]	acts_upstream_of_or_within	GO:0019079 viral genome replication	PMID:21810535
	located_in	GO:0019034 viral replication complex	PMID:21810535
PR:000044768 NS5 (DEN2N) UniProtKB:P14340, 2492-3391 \| PRO_0000037968 "An NS5 in Dengue virus 2 Thailand/NGS-C/1944. UniProtKB:P14340, 2492-3391." [PRO:DNx]	acts_upstream_of_or_within	GO:0001510 RNA methylation	PMID:21810535
		GO:0019079 viral genome replication	PMID:21810535
		GO:0042783 evasion of host immune response	PMID:21810535
	enables	GO:0003968 RNA-dependent RNA polymerase activity	PMID:21810535
		GO:0008168 methyltransferase activity	PMID:21810535
		GO:0070568 guanylyltransferase activity	PMID:23408612
	located_in	GO:0019034 viral replication complex	PMID:21810535
PR:000044770 prM (DEN2N) UniProtKB:P14340, 115-280, Asn-183, MOD:00160 \| PRO_0000261389, Asn-183, MOD:00160 "A prM in Dengue virus 2 Thailand/NGS-C/1944. UniProtKB:P14340, 115-280, Asn-183, MOD:00160." [PRO:DNx]	acts_upstream_of_or_within	GO:0006955 immune response	PMID:8429301
	located_in	GO:0019031 viral envelope	PMID:8429301