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Protein Ontology report - mitotic checkpoint serine/threonine-protein kinase BUB1 beta (frog)
PR:Q8JGT8 - http://purl.obolibrary.org/obo/PR_Q8JGT8
 
  Protein Forms  Complex  Annotations      
Ontology Information Show OBO stanza / PAF / GPI
  PRO ID
PR:Q8JGT8   
  PRO namemitotic checkpoint serine/threonine-protein kinase BUB1 beta (frog) 
  Synonyms
PRO-Short-label: EXACT:frog-BUB1B
Other: EXACT:xBUBR1
  Definition"A mitotic checkpoint serine/threonine-protein kinase BUB1 beta that is encoded in the genome of frog." [PMID:12163471, PMID:15241477, PMID:16950116, PRO:KER] 
  PRO Categoryorganism-gene 
  ParentPR:000004855 mitotic checkpoint serine/threonine-protein kinase BUB1 beta
PR:000036194 eukaryotic protein
  Gene TemplateNCBIGene:378923 bub1b (frog)
  TaxonNCBITaxon:8355 Xenopus laevis
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene0                                                  Organism-Gene 1                                        
         Sequence0                                                  Organism-Sequence 0                                        
         Modification0                                                  Organism-Modification 4                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:Q8JGT8
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Protein Forms  Switch to Extended View   

Category  
PRO Form Name
Ann. Has Annotation?

Comp. In Complex?
organism-gene


PR:Q8JGT8 mitotic checkpoint serine/threonine-protein kinase BUB1 beta (frog), frog-BUB1B
Yes
Yes
organism-modification


PR:000035425 mitotic checkpoint serine/threonine-protein kinase BUB1 beta unphosphorylated form (frog), frog-BUB1B/PhosRes-

organism-modification


PR:000035426 mitotic checkpoint serine/threonine-protein kinase BUB1 beta phosphorylated 1 (frog), frog-BUB1B/Phos:1
Yes
organism-modification


PR:000035430 mitotic checkpoint serine/threonine-protein kinase BUB1 beta CDK1- and PLK1-phosphorylated form (frog), frog-BUB1B/Phos:2
Yes
organism-modification


PR:000035433 mitotic checkpoint serine/threonine-protein kinase BUB1 beta phosphorylated 3 (frog), frog-BUB1B/Phos:3

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frog-BUB1B forms found in complexes   

frog-BUB1B Component
 Complexes
PR:Q8JGT8 frog-BUB1B PR:000035398 BUB1B:APC:EB1 complex (frog)
PR:000035512 BUB1B:BUB3:MAD2:CDC20 complex (frog)
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Functional Annotation (PRO-centric view) Switch to GO Centric View   
PRO Term GO Annotation Evidence
PR:000035426 frog-BUB1B/Phos:1
UniProtKB:Q8JGT8, Thr-605, MOD:00047 | BUBR1 phosphorylated (frog) | xBUBR1 phosphorylated
"A mitotic checkpoint serine/threonine-protein kinase BUB1 beta phosphorylated 1 in frog. UniProtKB:Q8JGT8, Thr-605, MOD:00047." [PMID:17998400, PRO:KER]		 acts_upstream_of_or_withinGO:0031577 spindle checkpoint signaling PMID:17998400
GO:0034501 protein localization to kinetochore PMID:17998400
GO:0034501 protein localization to kinetochore PMID:17998400
enablesincreased GO:0005515 protein binding with PR:P70032 frog-plk1 PMID:17998400
PR:000035430 frog-BUB1B/Phos:2
UniProtKB:Q8JGT8, Thr-605, MOD:00047|MOD:00696
"A mitotic checkpoint serine/threonine-protein kinase BUB1 beta CDK1- and PLK1-phosphorylated form in frog. This phosphorylation form is observed during mitosis and in conditions of spindle depolymerization (nocodazole). MAD1 is needed for this phosphorylation. UniProtKB:Q8JGT8, Thr-605, MOD:00047|MOD:00696." [PMID:12163471, PMID:17998400, PRO:KER]		 enablesincreased GO:0004672 protein kinase activity relative to PR:000035425 frog-BUB1B/PhosRes- PMID:17998400
PR:Q8JGT8 frog-BUB1B
xBUBR1
"A mitotic checkpoint serine/threonine-protein kinase BUB1 beta that is encoded in the genome of frog." [PMID:12163471, PMID:15241477, PMID:16950116, PRO:KER]		 acts_upstream_of_or_withinGO:0031577 spindle checkpoint signaling PMID:12163471
GO:0032092 positive regulation of protein binding PMID:12163471
GO:0032092 positive regulation of protein binding PMID:12163471
GO:0034501 protein localization to kinetochore PMID:17709426
GO:0034501 protein localization to kinetochore PMID:17709426
GO:0034501 protein localization to kinetochore PMID:17709426
GO:0034501 protein localization to kinetochore PMID:17709426
GO:0034501 protein localization to kinetochore PMID:17709426
GO:0034501 protein localization to kinetochore PMID:17709426
GO:0051310 metaphase chromosome alignment PMID:17709426
enablesGO:0004672 protein kinase activity PMID:12163471
GO:0005515 protein binding with PR:P70039 apc PMID:12163471
GO:0005515 protein binding with PR:P79935 frog-MAD2L1 PMID:12163471
GO:0005515 protein binding with PR:Q6DFD4 fizzy PMID:12163471
GO:0005515 protein binding with PR:Q9YGY3 bub3 PMID:12163471
GO:0005515 protein binding PMID:12163471
located_inGO:0000776 kinetochore PMID:12163471; PMID:17709426
GO:0005694 chromosome PMID:15241477; PMID:16950116