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Protein Ontology report - caspase-8 (human)
PR:Q14790 - http://purl.obolibrary.org/obo/PR_Q14790
 
  Protein Forms  Complex      
Ontology Information Show OBO stanza / GPI
  PRO ID
PR:Q14790   
  PRO namecaspase-8 (human) 
  Synonyms
PRO-Short-label: EXACT:hCASP8
Gene-based: RELATED:CASP8 | MCH5
Other: EXACT:apoptotic cysteine protease (human) | apoptotic protease Mch-5 (human) | CAP4 (human) | CASP-8 (human) | FADD-homologous ICE/ced-3-like protease (human) | FADD-like ICE (human) | FLICE (human) | ICE-like apoptotic protease 5 (human) | MACH (human) | MORT1-associated ced-3 homolog (human)
  Definition"A caspase-8 that is encoded in the genome of human." [PRO:DNx] 
  PRO Categoryorganism-gene 
  ParentPR:000002317 caspase-8
PR:000029067 Homo sapiens protein
  Gene TemplateHGNC:1509 CASP8 (human)
  TaxonNCBITaxon:9606 Homo sapiens
  Terms by PRO Category
Organism-Independent Organism-Specific
         Category          Number of Terms          Category          Number of Terms
         Gene0                                                  Organism-Gene 1                                        
         Sequence0                                                  Organism-Sequence 9                                        
         Modification0                                                  Organism-Modification 3                                        
  Term Hierarchy
  Visualization
DAG: OLS:
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Related Cross References

  Db identifiers
UniProtKB:Q14790
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Protein Forms  Switch to Extended View   

Category  

PRO Form Name

Short Name

Ann. Has Annotation?

Comp. In Complex?
organism-gene



PR:Q14790 caspase-8 (human)

hCASP8


Yes
organism-sequence



PR:Q14790-1 caspase-8 isoform 1 (human)

hCASP8/iso:1


organism-modification



PR:000036063 caspase-8 isoform 1 cleaved 1 (human)

hCASP8/iso:1/Clv:1


Yes
organism-modification



PR:000036065 caspase-8 isoform 1 cleaved 2 (human)

hCASP8/iso:1/Clv:2


Yes
organism-sequence



PR:Q14790-2 caspase-8 isoform 2 (human)

hCASP8/iso:2


organism-sequence



PR:Q14790-3 caspase-8 isoform 3 (human)

hCASP8/iso:3


organism-sequence



PR:Q14790-4 caspase-8 isoform 4 (human)

hCASP8/iso:4


organism-sequence



PR:Q14790-5 caspase-8 isoform 5 (human)

hCASP8/iso:5


organism-sequence



PR:Q14790-6 caspase-8 isoform 6 (human)

hCASP8/iso:6


organism-sequence



PR:Q14790-7 caspase-8 isoform 7 (human)

hCASP8/iso:7


organism-sequence



PR:Q14790-8 caspase-8 isoform 8 (human)

hCASP8/iso:8


organism-sequence



PR:Q14790-9 caspase-8 isoform 9 (human)

hCASP8/iso:9


organism-modification



PR:000045931 caspase-8 phosphorylated 1 (human)

hCASP8/Phos:1


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hCASP8 forms found in complexes   

hCASP8 Component
Complexes
PR:000036063 hCASP8/iso:1/Clv:1 PR:000036068 caspase-8 complex (human)
PR:000036065 hCASP8/iso:1/Clv:2 PR:000036068 caspase-8 complex (human)
PR:Q14790 hCASP8 PR:000028435 TRADD:TRAF2:RIP1:FADD:caspase-8 complex (human)
PR:000036060 pro-caspase-8:fadd:rip1:ticam1:ticam2:activated TLR4 complex (human)
PR:000037368 pro-caspase-8:fadd:rip1:ticam1:activated TLR3 complex (human)