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Protein Ontology Report - hSMURF1

PR:Q9HCE7 - http://purl.obolibrary.org/obo/PR_Q9HCE7
This page represents a class of proteins encompassing all the protein products of the SMURF1 gene in human.
Ontology Information
PRO ID PR:Q9HCE7 Show OBO stanza / PAF
PRO name E3 ubiquitin-protein ligase SMURF1 (human)
Synonyms
PRO-short-label: hSMURF1
EXACT: HECT-type E3 ubiquitin transferase SMURF1 (human); SMAD ubiquitination regulatory factor 1 (human); SMAD-specific E3 ubiquitin-protein ligase 1 (human)
Gene-based: KIAA1625; SMURF1
Definition An E3 ubiquitin-protein ligase SMURF1 that is encoded in the genome of human. [PRO:CNA, UniProtKB:Q9HCE7]
PRO Category organism-gene
Parent PR:000000361 E3 ubiquitin-protein ligase SMURF1
Gene Template HGNC:16807 SMURF1
Taxon NCBITaxon:9606 Homo sapiens
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Specific
Category Number of Terms
organism-gene 1
organism-sequence 2
organism-modification 0
Term Hierarchy Visualization DAG     OLS     Cytoscape


Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

Functional Annotation
PRO Term GO Annotation Evidence
PR:Q9HCE7
hSMURF1
participates_in GO:0030514 negative regulation of BMP signaling pathway PMID:10458166
PR:Q9HCE7-2
hSMURF1/iso:Short
capable_of GO:0004842 ubiquitin-protein transferase activity PMID:10458166
capable_of GO:0005515 protein binding PMID:11278251, PMID:16299379
located_in GO:0005622 intracellular anatomical structure PMID:10458166
participates_in GO:0006511 ubiquitin-dependent protein catabolic process PMID:10458166
participates_in GO:0030579 ubiquitin-dependent SMAD protein catabolic process PMID:12857866
participates_in GO:0006464 cellular protein modification process PMID:10458166
Biological Process GO Term Protein Forms & Complexes Evidence
GO:0030514 negative regulation of BMP signaling pathway PR:Q9HCE7 hSMURF1

PMID:10458166
GO:0006511 ubiquitin-dependent protein catabolic process PR:Q9HCE7-2 hSMURF1/iso:Short

PMID:10458166
GO:0030579 ubiquitin-dependent SMAD protein catabolic process PR:Q9HCE7-2 hSMURF1/iso:Short

PMID:12857866
GO:0006464 cellular protein modification process PR:Q9HCE7-2 hSMURF1/iso:Short

PMID:10458166
Cellular Location GO Term Protein Forms & Complexes Evidence
GO:0005622 intracellular anatomical structure PR:Q9HCE7-2 hSMURF1/iso:Short

PMID:10458166

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