Protein Ontology Report - CCND1 PR:000005121 - http://purl.obolibrary.org/obo/PR_000005121

Ontology Information
PRO ID	PR:000005121 Show OBO stanza / PAF
PRO name	G1/S-specific cyclin-D1
Synonyms	PRO-short-label: EXACT: CCND1 Gene-based: RELATED: BCL1 | Cyl-1 | PRAD1 Other: EXACT: B-cell lymphoma 1 protein | BCL-1 | BCL-1 oncogene | PRAD1 oncogene
Definition	A cyclin-D that is a translation product of the human CCND1 gene or a 1:1 ortholog thereof. [PRO:DNx]
PRO Category	gene
Parent	PR:000050022 cyclin-D
Terms by PRO Category	Retrieve All terms OBO Stanza / PAF Organism-Independent Organism-Specific Category Number of Terms Category Number of Terms gene 1 organism-gene 5 sequence 1 organism-sequence 3 modification 1 organism-modification 4 union 0
Term Hierarchy Visualization	DAG     OLS     Cytoscape

Interactive Sequence View Select/align proteoforms across species

Protein Forms Display Category: All All gene organism-gene sequence organism-sequence modification organism-modification
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

CCND1 forms found in complexes
CCND1 Component Complexes PR:000005121 CCND1 PR:000026740 cyclin D1:Cdk4 PR:000027131 CCND1/Phos:1 PR:000027140 cyclin D1:Cdk4 complex phosphorylated 1 PR:000027132 hCCND1/Phos:1 PR:000027150 cyclin D1:Cdk4 complex phosphorylated 1 (human) PR:P24385 hCCND1 PR:000026741 cyclin D1:Cdk4 (human)

Functional Annotation PRO Centric View GO Centric View
PRO Term GO Annotation Evidence PR:000027132 hCCND1/Phos:1 Thr-286, MOD:00047 enables GO:0005515 protein binding increased relative to PR:000037511 hCCND1/UnPhos:1 with PR:000037513 FBXO4:CRYAB:Skp1:Cul1:Rbx1 complex (human) PMID:17407548 PR:000037511 hCCND1/UnPhos:1 Thr-286, PR:000026291 associated_with_disease_progression DOID:162 cancer PMID:17407548

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