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Protein Ontology Report - CCND1

PR:000005121 - http://purl.obolibrary.org/obo/PR_000005121
Ontology Information
PRO ID PR:000005121 Show OBO stanza / PAF
PRO name G1/S-specific cyclin-D1
Synonyms
PRO-short-label: EXACT: CCND1
Gene-based: RELATED: BCL1 | Cyl-1 | PRAD1
Other: EXACT: B-cell lymphoma 1 protein | BCL-1 | BCL-1 oncogene | PRAD1 oncogene
Definition A cyclin-D that is a translation product of the human CCND1 gene or a 1:1 ortholog thereof. [PRO:DNx]
PRO Category gene
Parent PR:000050022 cyclin-D
Terms by PRO Category Retrieve All terms OBO Stanza / PAF
Organism-Independent Organism-Specific
Category Number of Terms Category Number of Terms
gene 1 organism-gene 5
sequence 1 organism-sequence 3
modification 1 organism-modification 4
union 0
Term Hierarchy Visualization DAG     OLS     Cytoscape

Interactive Sequence View Select/align proteoforms across species

Protein Forms
PRO ID & Category Annotation Complex Name Short Label Definition & Comment

CCND1 forms found in complexes
CCND1 Component Complexes
PR:000005121 CCND1 PR:000026740 cyclin D1:Cdk4
PR:000027131 CCND1/Phos:1 PR:000027140 cyclin D1:Cdk4 complex phosphorylated 1
PR:000027132 hCCND1/Phos:1 PR:000027150 cyclin D1:Cdk4 complex phosphorylated 1 (human)
PR:P24385 hCCND1 PR:000026741 cyclin D1:Cdk4 (human)

Functional Annotation
PRO Term GO Annotation Evidence
PR:000027132
hCCND1/Phos:1
Thr-286, MOD:00047
capable_of GO:0005515 protein binding increased relative to PR:000037511 hCCND1/UnPhos:1 with PR:000037513 FBXO4:CRYAB:Skp1:Cul1:Rbx1 complex (human) PMID:17407548
PR:000037511
hCCND1/UnPhos:1
Thr-286, PR:000026291
associated_with_disease_progression DOID:162 cancer PMID:17407548
Molecular Function GO Term Protein Forms & Complexes Evidence
GO:0005515 protein binding PR:000027132 hCCND1/Phos:1
Thr-286, MOD:00047
increased relative to PR:000037511 hCCND1/UnPhos:1 with PR:000037513 FBXO4:CRYAB:Skp1:Cul1:Rbx1 complex (human)
PMID:17407548

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